NIGMS-supported research on the basic biology on human embryonic stem cells (hESC) and induced pluripotent stem cells (iPSC) was the focus of this recent workshop, which brought together members of three program projects for basic research on human embryonic stem cells and three program projects on the basic biology of pluripotency and reprogramming. The meeting was an opportunity to share recent advances, discuss technologies and analytical tools, and consider the future of this exciting and fast-moving research area.
The talks and posters focused on several broad areas of hESC and iPSC research: pluripotency and self-renewal, exiting pluripotency and differentiation, reprogramming and cell fate conversions, and genomics and genome architecture. Following one-and-a-half days of scientific presentations, the workshop concluded with a discussion of future directions and challenges. Topics ranged from the challenges of computationally modeling cell state dynamics for predicting complex cell behaviors to the opportunities for using iPSC models to identify causative mutations among the large number of variants found by whole genome sequencing.
The full agenda and list of registered participants are below.
Monday, March 10, 2014Natcher Conference Center Room D
Tuesday, March 11, 2014Natcher Conference Center Room D
Justin BeckerGraduate StudentCell and Developmental BiologyUniversity of Pennsylvania School of Medicine3400 Civic Center Blvd., Rm. 9-167Smilow Center for Translational Research, Bldg. 42Philadelphia, PA 19104E-mail: justinbe@mail.med.upenn.edu
Kaytlyn Beres Graduate StudentBioengineeringUniversity of WashingtonCenter for Cardiovascular Biology850 Republican StreetRoom 454Seattle, WA 98109E-mail: kaberes@uw.edu
Davide Cacchiarelli Stem Cell and Regenerative BiologyHarvard University7 Divinity AvenueCambridge, MA 02138E-mail: davide.kun@gmail.com
James ChappellGraduate StudentUniversity of Georgia180 Normal AvenueAthens, GA 30606E-mail: jchap14@gmail.com
Konstantinos ChronisPostdoctoral FellowBiological ChemistryUCLABSRB 354Los Angeles, CA 90095E-mail: k1chronis@gmail.com
Tim Cliff Graduate StudentBiochemistry and Molecular BiologyUniversity of Georgia500 D.W. Brooks DriveAthens, GA 30605E-mail: clifftim@uga.edu
Victor Corces ProfessorEmory University1510 Clifton RoadRollins Research Center, Room 1071BAtlanta, GA 30322E-mail: vcorces@emory.edu
Stephen Dalton Department of Biochemistry and Molecular BiologyUniversity of Georgia500 D.W. Brooks DriveAthens, GA 30602E-mail: sdalton@uga.edu
Miguel Edwards UCLA675 Charles E. Young Drive SouthLos Angeles, CA 90095E-mail: migs54@gmail.com
Kevin EgganProfessorStem Cell and Regenerative BiologyHarvard University7 Divinity Avenue, SF #258Cambridge, MA 02138E-mail: eggan@mcb.harvard.edu
Meilin Fernandez Graduate StudentBiochemistry and Molecular BiophysicsUniversity of PennsylvaniaSmilow Center for Translational Research3400 Civic Center Blvd., Rm. #9-166Philadelphia, PA 19104E-mail: meilinfe@mail.med.upenn.edu
Xavier Gaeta Graduate StudentUCLA621 Charles E. Young DriveBiological Sciences Research Building 457Los Angeles, CA 90095E-mail: xgaeta@ucla.edu
Igal GermanguzPostdoctoral FellowMCDB/UCLA1431 S. Shenandoah Street #10Los Angeles, CA 90035E-mail: germanguz@ucla.edu
David Gilbert Florida State University319 Stadium DriveTallahassee, FL 32306-4295E-mail: gilbert@bio.fsu.edu
Susan Haynes Program DirectorNIGMS45 Center DriveBethesda, MD 20892E-mail: sh494m@nih.gov
Kavitha Kuppusamy University of Washington850 Republican StreetSeattle, WA 98109E-mail: kavithak@uw.edu
Anna La TorrePostdoctoral FellowBiological Structure, University of Washington1959 Pacific Street NESeattle, WA 98195E-mail: annalt@uw.edu
Justin Langerman UCLALos Angeles, CA 90066E-mail: ikari999@ucla.edu
Li Li Biostatistics and BioinformaticsEmory University1518 Clifton Road NERoom 327Atlanta, GA 30322E-mail: lilisysbio@gmail.com
Jing LiaoPostdoctoral FellowStem Cell and Regenerative BiologyHarvard University7 Divinity AvenueBauer 208Cambridge, MA 02138E-mail: jing_liao@harvard.edu
Jon Lorsch Director, NIGMSBldg. 45, Rm. 3AN.4445 Center DriveBethesda, MD 20892E-mail: jon.lorsch@nih.gov
William Lowry UCLA621 Charles Young DriveLos Angeles, CA 90077E-mail: blowry@ucla.edu
Alexander Meissner Harvard University7 Divinity AvenueCambridge, MA 02138E-mail: alexander_meissner@harvard.edu
Florian Merkle Stem Cell and Regenerative BiologyHarvard University7 Divinity AvenueSF 216Cambridge, MA 02138E-mail: fmerkle@fas.harvard.edu
Tarjei MikkelsenBroad Technology LabsBroad Institute320 Charles Street, Room 2265Cambridge, MA 02142E-mail: tarjei@broadinstitute.org
Charles MurryUniversity of Washington850 Republican StreetBrotman Building, Room 454Seattle, WA 98109E-mail: murry@uw.edu
Nathan PalpantPostdoctoral FellowPathologyUniversity of Washington850 Republican StreetSeattle, WA 98109E-mail: npalpant@uw.edu
Kathrin Plath Associate ProfessorDepartment of Biological ChemistryUCLA School of Medicine615 Charles E. Young Drive SouthBSRB 390DLos Angeles, CA 90095E-mail: kplath@mednet.ucla.edu
Steve Qin Emory UniversityGCR338, 1518 Clifton Road NEDepartment of Biostatistics and BioinformaticsAtlanta, GA 30322E-mail: zhaohui.qin@emory.edu
John RinnAssociate ProfessorHarvard University7 Divinity Avenue, Room 305Cambridge, MA 02138E-mail: john_rinn@harvard.edu
Juan Carlos Rivera-Mulia Postdoctoral FellowBiological Science, Florida State University319 Stadium DriveTallahassee, FL 32306-4295E-mail: riveramjc@bio.fsu.edu
Walter Ruzzo ProfessorUniversity of WashingtonBox 352350Seattle, WA 98195E-mail: ruzzo@uw.edu
Amar SinghPostdoctoral AssociateBiochemistry and Molecular BiologyUniversity of Georgia500 D.W. Brooks DrivePaul D. Coverdell CenterAthens, GA 30602E-mail: singha@uga.edu
Stephen SmaleProfessorMicrobiology, Immunology, and Molecular GeneticsUCLA, 1602B MSB, UCLALos Angeles, CA 90095E-mail: smale@mednet.ucla.edu
Michael SnyderProfessor and ChairGeneticsStanford University300 Pasteur Drive M344Stanford, CA 94305E-mail: mpsnyder@stanford.edu
Abdenour Soufi Postdoctoral AssociateUniversity of PennsylvaniaPerelman School of Medicine, CDB DepartmentSmilow Center for Translational Research, Bldg. 21Room 166, 3400 Civic Center BoulevardPhiladelphia, PA 19104-5157E-mail: asoufi@upenn.edu
Rajini Srinivasan Research AssistantStanford University265 Campus DriveSIM1 Lokey BuildingRoom G3065Stanford, CA 94305E-mail: rajinis@stanford.edu
Yuhua Sun University of Georgia245# Coverdell Center, UGAAthens, GA 30602E-mail: yhsun@uga.edu
Alex TsankovPostdoctoral FellowStem Cell and Regenerative BiologyHarvard University7 Divinity AvenueBauer 208Cambridge, MA 02138E-mail: atsankov@broadinstitute.org
Guangwen Wang Director, Stem Cell CoreStanford University265 Campus Drive West SIM1 G1165AStanford, CA 94305E-mail: gavin.wang@stanford.edu
Korey Wilson Florida State University319 Stadium DriveTallahassee, FL 32306E-mail: kwilson@bio.fsu.edu
Yuan Xie Ph.D. CandidateMCDBUCLALos Angeles, CA 90034E-mail: xieyuanmail@gmail.com
Chenhuan Xu Emory University1510 Clifton RoadRollins Research Building, Room 1071BAtlanta, GA 30322E-mail: chenhuan.xu@emory.edu
Ken ZaretProfessorUniversity of PennsylvaniaInstitute for Regenerative MedicineDepartment of Cell and Developmental Biology3400 Civic Center Boulevard, Building 421Philadelphia, PA 19104E-mail: zaret@upenn.edu
