National Institute of General Medical SciencesNational Institutes of HealthDecember 21, 2010
"A good idea is a network." - Steven Johnson,Where Good Ideas Come From: The Natural History of Innovation
The PSI:Biology program seeks to leverage the high-throughput technology developed during the 10 years of the Protein Structure Initiative (PSI) for the solution of important and complex biological problems through a partnership with laboratories expert in the biological systems being studied. Key to the success of these programs is networking of novel technologies to establish protein production and structure determination pipelines, networking among the high-throughput centers (HTC) to spur technology development and networking of the centers with their program partners so that the novel high-throughput technology can be innovatively applied to the biologically important and technically demanding problems that have been proposed. Lastly, but no less important, is networking of PSI:Biology as a whole with the biomedical community so that insight and technology is rapidly and broadly disseminated.
Based on the reports and discussions of the PSI:Biology kick-off pre-meeting in July 2010 and first annual meeting in December 2010, it is clear that significant progress has been made in establishing each of the above mentioned networks as well as establishing the individual partners programs. Members of the Advisory Committee who served during PSI-1 and/or -2 commented on the freshness of the meeting discussions that now include the biological partners. Each biological program and each membrane center has "hit the ground running" and is moving their work rapidly forward with their partner HTC. The PSI Knowledgebase and Materials Repository are likewise gearing up for the onslaught of information and material that will be generated by PSI:Biology. Below we briefly summarize key issues that were raised during the annual meeting and feedback the Advisory Committee offers to help insure success of the program, particularly during the critical early stages.
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