The most recent SCORE Notice of Funding Opportunities (NOFO) are available at:

• Research Advancement Award (SC1) - PAR-20-039
• Pilot Project Award (SC2) - PAR-20-040
• Research Continuance Award (SC3) - PAR-20-041

The submission/receipt dates are January 25, 2020, May 25, 2020; January 25, 2021, May 25, 2021; January 25, 2022, May 25, 2022. For AIDS applications: May 7, 2020, September 7, 2020; May 7, 2021, September 7, 2021; May 7, 2022, September 7, 2022. Since applications must be submitted electronically, they must be successfully received by Grants.gov no later than 5:00 p.m. local time (of the applicant institution/organization) in order to be considered "on time."

Note that AIDS applications undergoing expedited review will be assigned to the most appropriate Scientific Review Group (SRG) in the Center for Scientific Review.

SCORE applications may be submitted by institutions that have an explicitly stated historical mission focused on training and graduating students from backgrounds underrepresented in biomedical and behavioral research. In addition, eligible institutions must award science degrees to undergraduate (B.S. or B.A.) and/or graduate students (M.S. or Ph.D.) and have received less than $6 million dollars of NIH R01 support in each of the last 2 fiscal years.

Most institutions of higher learning have mission statements that identify an institution’s purpose and the reason for its creation as well as the student populations that it seeks to educate and serve. If your institution's mission statement explicitly states that its historical mission is to educate students from any of the populations that have been identified as underrepresented in biomedical research as defined in NIH NOT-OD-15-053 your institution would meet the first prong of the SCORE NOFO's eligibility requirement.

Some institutions might not have the explicit language in their mission statements but they may make the case that they have a demonstrable history of training and graduating substantial numbers of students from backgrounds underrepresented in biomedical research and contributing substantially to the national pool of underrepresented individuals who pursue biomedical research careers as evidenced by institutional data from at least the last 10 years.

As explained under Section IV.2 (Application and Submission Information) of the SCORE NOFOs, the evidence of the institution's historical mission and/or a historical record of training and graduating students from backgrounds underrepresented in biomedical research (as defined above) and contribution to the national pool of underrepresented individuals who pursue biomedical research careers is required as part of the other project information part of the application. Otherwise, the application will be considered incomplete and will not be reviewed.

Note that SCORE eligibility cannot be determined before an application is submitted. All the required information will be assessed during the peer review process. Institutions that receive support from the Initiative for Maximizing Student Development (IMSD) are not eligible to apply/hold SCORE awards.

Eligible institutions may submit/hold a maximum of 20 individual investigator-initiated SCORE awards. Applications submitted/awarded in excess of this cap will be withdrawn.

Even though faculty will be the PIs of SCORE SC individual awards, the fiduciary responsibility for applying and receiving an NIH award resides in the institution. Additionally, in the case of SCORE, it is strongly recommended that the institution have a plan to: 1) determine which faculty members are best suited for SCORE participation based on their developmental/enhancement goals and needs, 2) track the number of submitted/awarded individual SCORE applications to keep the total number under the maximum allowed of 20 per year and 3) assist applicants with the electronic submission and post-award management of their applications.

Only full-time individuals on regular faculty appointments may apply for SCORE SC awards if they are seeking to develop their research competitiveness and eventually transition to non-SCORE support. Postdoctoral fellows, research or teaching instructors, research assistant professors, research scientists, other research appointments or appointments contingent on an individual securing his/her salary from grants, part time or adjunct faculty and faculty who have joint appointments in which one is at a research intensive institution are not eligible to apply for SCORE individual awards. Emeritus or distinguished/retired investigators/professors as well as individuals with a track record of research support, e.g. R01 or other research grant awards from federal or non-federal sources and publications are considered to be fully developed and may not apply for this award (see next question). Current PD/PIs of R01 or of other investigator initiated federal or non-federal research awards or of program projects, center grants, cooperative agreements or other institutional research awards are ineligible to apply for/receive any of the SCORE awards.

Investigators who have developmental/enhancement grant support with goals similar to SCORE are ineligible to apply for SC awards until the completion of these awards, i.e., SCORE awards are not intended to duplicate other individual or institutional developmental awards; these include K awards and research support provided as part of institutional centers, program projects, cooperative agreements such as from COBRE, INBRE, RCMI, BUILD, etc.

Note that at the time a SCORE SC1 or SC2 award is made, PIs cannot have any other active research support. In the case of a SCORE SC3, a PI can have up to $75,000 total costs of other active research support at the time of an award provided there is no scientific overlap between these grants and the other project is also for a project of limited scope.

The following investigators (PIs) are considered to be fully developed and are not eligible to apply for any of the SCORE individual awards:

• Faculty who have had a track record of significant non-SCORE external support (i.e., more than one funding cycle of NIH, NSF, or other federal or non-federal support);
• Faculty who have current R01 or other NIH research (R) support, NSF support, or other significant federal support or foundation grants;
• Retired or emeritus professors;
• Endowed or distinguished professors;
• Directors, co-directors of research centers;
• Faculty who are productive PIs or co-Principal investigators of major program projects (e.g. P01, P20, U54, G12, RCMI, INBRE, COBRE, etc.);
• Faculty who have received grants based on their distinguished research accomplishments or special research recognition awards (e.g. PECASE awardees);
• Faculty who have achieved the SCORE goal of transitioning to non-SCORE research support (e.g., R01, R15, P01, NSF or other federal or non-federal agency awards); and
• Faculty at SCORE-eligible institutions who also have a research appointment at a research institution or center.
• Faculty on research appointments and/or affiliated with research centers.

No. Only full-time individuals on regular faculty appointments may apply for individual SCORE awards. Research track appointments are not considered regular full-time faculty appointments. Thus, research assistant instructors, research assistant professors and research scientists are not eligible to apply for SCORE individual awards.

No. SCORE enhancement awards focus on the research development/enhancement of a single PI.

Eligible PIs planning to apply for an SC award should conduct a self-assessment of their research project, research productivity and career goals to be able to determine which mechanism is more suitable for them. Recommended areas of assessment include the PI's expertise and research productivity, project's goals and fit with the NIH mission, need for mentors or collaborators, etc.

The Research Portfolio Online Reporting Tool (RePORT) allows you to perform searches of descriptions (abstracts) of funded grants using specific key words.

The National Institute of Allergy and Infectious Diseases' website has useful information on how to prepare an application and also offers sample applications (https://www.niaid.nih.gov/grants-contracts/apply-grant).

The TWD Division also sponsors a Grant Writing Workshop for faculty at SCORE-eligible institutions who already have a draft SC or other research application with well-defined specific aims and research strategy. This workshop is offered by University of Kentucky staff every year.

Yes, as indicated in NIH Guide Notice NOT-OD-15-032, all SCORE applications submitted on or after May 25, 2015, are required to use the new biographical sketch format. It is also important to note that there are new instructions in the SCORE NOFOs that specify that the PI's Research Enhancement Plan (which must present the PI's research enhancement objectives and plan) as well as the SC2 Advisor's Role in the Research Enhancement Plan must be included in the attachment for "Other Project Information" (see Section IV of the SCORE NOFO).

Yes, all of the SCORE SC award applications require that a PI research enhancement plan be provided as part of "Other Project Information" (see Section IV of the NOFO). This plan must include the PI's research career enhancement objectives and a plan and timeline to achieve them. The research enhancement objectives must be consistent with the goals of each individual mechanism (see the SC1, SC2 and SC3 notice of funding opportunities on the SCORE website for further details) and demonstrate how the PI's research competitiveness and productivity will increase as a result of SCORE funding.

The plan must justify the need for development and provide an explanation of how the proposed project and the time devoted to it will help the PI further his/her research competitiveness and significantly improve his/her productivity. A timeline for the transition to non-SCORE support must be provided for SC1 applicants. The developmental plan should show a logical progression from the candidate's current support to the SCORE SC1, SC2 or SC3 support and to transition to non-SCORE support.

Note that applications that lack a research career enhancement objectives and/or plan are considered incomplete and will be withdrawn prior to review.

Mentorship or advisement from an experienced investigator in the proposed research area is required to facilitate a PI's research development. Note that the role of the mentor in the PI's research enhancement plan must be explained in detail and presented as part of Other project information (see Section IV of NOFO​). Note that a letter from the mentor is not required as part of an SC2 application.

In the advisor’s role, the advisor must include: 1) his/her research qualifications and his/her previous experience as a research advisor; 2) nature of his/her mentoring role and how s/he will assist the PD/PI in his/her research development, 3) frequency of the supervision and how the applicant’s progress toward specified milestones will be monitored.

An SC2 mentor must be an accomplished, well-funded, active investigator in a research area. He/she is expected also to: 1) work with the mentee on the development of the SC2 proposal and 2) have a successful track record of advising/mentoring individuals who succeeded in getting independent research support.

Note that foreign advisor/mentors are not allowed.

SC2 awards require a minimum effort of 50 percent of a full-time appointment at the applicant institution equivalent to 6 person months.

Consultants from outside the applicant institution are individuals who have committed to contributing intellectually to the scientific project development or its execution, but are not committing any specified measurable effort (in person months). These individuals are typically presented as "effort of 0 person months" or "as needed." This would also be the appropriate way of designating the role/effort of a mentor on a project.

Collaborators, who are recognized experts in a field from the applicant institution or another institution, generally provide expertise in a very specific aspect of the execution of the proposed project in which the PI does not have any experience or has limited experience, (e.g., with a research protocol, running a test on some samples, etc.). Travel for external domestic collaborators or for the PI to visit the collaborator's laboratory is allowed.

Consultants and collaborators must have their own research support. SCORE funds cannot be used to fund a consultant or external collaborator's research project or to pay their effort in person months. However, consultants can be paid a modest honorarium. Letters from the proposed consultants and/or collaborators specifying their role in the project and their biographical sketches must be included in the grant application.

Note that foreign collaborators/consultants are not allowed.

Postdoctoral fellows may only be requested on SC1 awards provided that: 1) the research proposed justifies the need for their particular expertise and 2) their participation in the proposed research project will further their professional career. It is also required that the postdoctoral fellow be employed in a research-rich environment in which he/she will have opportunity to be an independent thinker and to develop by participating in mentoring activities and interacting with other postdocs, Ph.D. students and research faculty. Justification for a postdoctoral fellow and his/her specific role/time on a project is required as part of "personnel justification" in the modular budget format. This justification must include: 1) a professional and research development plan for the postdoctoral fellow which should detail the mentoring activities he/she and other postdoctoral fellows at the institution will be engaged in (e.g., career counseling, grant writing, training in research ethics, teaching, etc.), 2) a description of the postdoctoral fellow's involvement in the project as well as his/her anticipated time commitment and other obligations, 3) a brief description of the number of postdoctoral peers/Ph.D. students/research faculty with whom he will be able to interact in the lab, and 4) a brief narrative of the track record of the PI in training postdoctoral fellows, particularly from underrepresented groups.

No. Modular budgets are required of all SCORE individual applications.

Per the SF424 application instructions, detailed information on the following items must be included in the modular budget justification narrative:

• Personnel: List all personnel, including names, number of person months devoted to the project (indicate academic, calendar and/or summer) and a detailed explanation of their roles on the project.
• Consortium Arrangements: Provide a breakdown of the direct and indirect costs for each year (rounded to the nearest $1,000). List the individuals/organizations with whom consortium or contractual arrangements have been made, along with all personnel, including percent of effort (in person months) and roles on the project. NOTE: Consortium arrangements are only allowed with SCORE-funded institutions.
• Miscellaneous: A typical modular grant application will request the same number of modules in each year. A separate narrative justification must be provided explaining any deviation in the number of modules requested each year.

Yes. Per the SF424 application instructions, you must point out any procedures, situations or materials that may be hazardous to personnel and the safety precautions to be exercised.

Yes, you must follow the new application guidelines as per NOT-OD-16-011 (see Updated Application Instructions to Enhance Rigor and Reproducibility for more details).

No. SCORE enhancement awards focus on the research development/enhancement of a single PI. Please note NIH uses the term co-investigator to mean collaborator. The term co-Principal Investigator (i.e., co-PI) should not be used to refer to a collaborator.

Applicants must follow the specific instructions on Appendix materials as described in NOT-OD-17-035.

An SC3 or SC1 application would constitute a new application. In a new application, elements of a renewal or resubmission are not allowed (see NOT-OD-15-059), including a progress report. However, preliminary studies are expected in SC3 and SC1 applications and should include preliminary studies, data or experience resulting from the SC award, since an SC3 or SC1 application represents an appropriate developmental mechanism in the research career progression of SCORE PIs. Remember also that preliminary data can be an essential part of a research grant application and can help establish the likelihood of success of the proposed project.

The same guidelines and advice would apply when an SC3 PI applies for an SC1.

No, the SCORE program does not support clinical trials or clinical interventions.

The first submission of an application in response to any of the SCORE individual awards will be considered a new application.