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Dolly the sheep
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Scientists in Scotland were the first to clone an animal, this sheep named Dolly. She later gave birth to Bonnie, the lamb next to her. View Media
Pigment cells in the fin of pearl danio
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Pigment cells are cells that give skin its color. David Parichy, University of Washington View Media
Biofilm formed by a pathogen
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A biofilm is a highly organized community of microorganisms that develops naturally on certain surfaces. Scott Chimileski, Ph.D., and Roberto Kolter, Ph.D., Harvard Medical School. View Media
Mitotic cell awaits chromosome alignment
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During mitosis, spindle microtubules (red) attach to chromosome pairs (blue), directing them to the spindle equator. View Media
Yeast cell
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A whole yeast (Saccharomyces cerevisiae) cell viewed by X-ray microscopy. Inside, the nucleus and a large vacuole (red) are visible. Carolyn Larabell, University of California, San Francisco and the Lawrence Berkeley National Laboratory View Media
Hydra 05
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Hydra magnipapillata is an invertebrate animal used as a model organism to study developmental questions, for example the formation of the body axis. Hiroshi Shimizu, National Institute of Genetics in Mishima, Japan View Media
Fruit fly spermatids
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Developing spermatids (precursors of mature sperm cells) begin as small, round cells and mature into long-tailed, tadpole-shaped ones. Lacramioara Fabian, The Hospital for Sick Children, Toronto, Canada View Media
Human ES cells differentiating into neurons
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This image shows hundreds of human embryonic stem cells in various stages of differentiating into neurons. Guoping Fan lab, University of California, Los Angeles, via CIRM View Media
Vibrio bacteria
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Vibrio, a type (genus) of rod-shaped bacteria. Some Vibrio species cause cholera in humans. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media
Cancer Cells Glowing from Luciferin
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The activator cancer cell culture, right, contains a chemical that causes the cells to emit light when in the presence of immune cells. Mark Sellmyer, Stanford University School of Medicine View Media
Z rings in bacterial division
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Lab-made liposomes contract where Z rings have gathered together and the constriction forces are greatest (arrows). Masaki Osawa, Duke University View Media
Human retinal organoid
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A replica of a human retina grown from stem cells. Kevin Eliceiri, University of Wisconsin-Madison. View Media
Precisely Delivering Chemical Cargo to Cells
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Moving protein or other molecules to specific cells to treat or examine them has been a major biological challenge. Nature Nanotechnology View Media
Simulation of leg muscles moving
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When we walk, muscles and nerves interact in intricate ways. This simulation, which is based on data from a six-foot-tall man, shows these interactions. Chand John and Eran Guendelman, Stanford University View Media
A panorama view of cells
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This photograph shows a panoramic view of HeLa cells, a cell line many researchers use to study a large variety of important research questions. Tom Deerinck, National Center for Microscopy and Imaging Research View Media
Pulsating response to stress in bacteria - video
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By attaching fluorescent proteins to the genetic circuit responsible for B. subtilis's stress response, researchers can observe the cells' pulses as green flashes. Michael Elowitz, Caltech University View Media
Endoplasmic reticulum
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Fluorescent markers show the interconnected web of tubes and compartments in the endoplasmic reticulum. The protein atlastin helps build and maintain this critical part of cells. Andrea Daga, Eugenio Medea Scientific Institute (Conegliano, Italy) View Media
Genetically identical mycobacteria respond differently to antibiotic 1
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Antibiotic resistance in microbes is a serious health concern. So researchers have turned their attention to how bacteria undo the action of some antibiotics. Bree Aldridge, Tufts University View Media
Leptospira bacteria
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Leptospira, shown here in green, is a type (genus) of elongated, spiral-shaped bacteria. Infection can cause Weil's disease, a kind of jaundice, in humans. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media
Peripheral nerve cells derived from ES cells
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Peripheral nerve cells made from human embryonic stem cell-derived neural crest stem cells. Stephen Dalton, University of Georgia View Media
Mouse cerebellum close-up
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The cerebellum is the brain's locomotion control center. Every time you shoot a basketball, tie your shoe or chop an onion, your cerebellum fires into action. National Center for Microscopy and Imaging Research (NCMIR) View Media
Dense tubular matrices in the peripheral endoplasmic reticulum (ER) 2
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Three-dimensional reconstruction of a tubular matrix in a thin section of the peripheral endoplasmic reticulum between the plasma membranes of the cell. Jennifer Lippincott-Schwartz, Howard Hughes Medical Institute Janelia Research Campus, Virginia View Media
Wound healing in process
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Wound healing requires the action of stem cells. Hermann Steller, Rockefeller University View Media
RAC1 activation in motile fibroblast
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Novel biosensor system maps the timing and location of Rac protein activation in a living mouse embryo fibroblast. Klaus Hahn, University of North Carolina, Chapel Hill Medical School View Media
Quartered torso
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Cells function within organs and tissues, such as the lungs, heart, intestines, and kidney. Judith Stoffer View Media
Single-cell “radios” image
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Individual cells are color-coded based on their identity and signaling activity using a protein circuit technology developed by the Coyle Lab. Scott Coyle, University of Wisconsin-Madison. View Media
Atomic-level structure of the HIV capsid
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This animation shows atoms of the HIV capsid, the shell that encloses the virus's genetic material. Juan R. Perilla and the Theoretical and Computational Biophysics Group, University of Illinois at Urbana-Champaign View Media
Stem cell differentiation
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Undifferentiated embryonic stem cells cease to exist a few days after conception. In this image, ES cells are shown to differentiate into sperm, muscle fiber, hair cells, nerve cells, and cone cells. Judith Stoffer View Media
Cerebellum: the brain's locomotion control center
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The cerebellum of a mouse is shown here in cross-section. The cerebellum is the brain's locomotion control center. Thomas Deerinck, National Center for Microscopy and Imaging Research, University of California, San Diego View Media
Dividing cell in metaphase
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This image of a mammalian epithelial cell, captured in metaphase, was the winning image in the high- and super-resolution microscopy category of the 2012 GE Healthcare Life Sciences Cell Imaging Compe Jane Stout in the laboratory of Claire Walczak, Indiana University, GE Healthcare 2012 Cell Imaging Competition View Media
NCMIR human spinal nerve
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Spinal nerves are part of the peripheral nervous system. They run within the spinal column to carry nerve signals to and from all parts of the body. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
NCMIR Kidney Glomeruli
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Stained glomeruli in the kidney. The kidney is an essential organ responsible for disposing wastes from the body and for maintaining healthy ion levels in the blood. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
Cell-like compartments from frog eggs
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Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media
Soft X-ray tomography of a pancreatic beta cell
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A color-coded, 3D model of a rat pancreatic β cell. This type of cell produces insulin, a hormone that helps regulate blood sugar. Carolyn Larabell, University of California, San Francisco. View Media
Vimentin in a quail embryo
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Video of high-resolution confocal images depicting vimentin immunofluorescence (green) and nuclei (blue) at the edge of a quail embryo yolk. Andrés Garcia, Georgia Tech View Media
Mitochondrion from insect flight muscle
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This is a tomographic reconstruction of a mitochondrion from an insect flight muscle. National Center for Microscopy and Imaging Research View Media
Sea urchin embryo 05
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Stereo triplet of a sea urchin embryo stained to reveal actin filaments (orange) and microtubules (blue). George von Dassow, University of Washington View Media
Tracking cells in a gastrulating zebrafish embryo
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During development, a zebrafish embryo is transformed from a ball of cells into a recognizable body plan by sweeping convergence and extension cell movements. This process is called gastrulation. Liliana Solnica-Krezel, Washington University School of Medicine in St. Louis. View Media
Cytonemes in developing fruit fly cells
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Scientists have long known that multicellular organisms use biological molecules produced by one cell and sensed by another to transmit messages that, for instance, guide proper development of organs Sougata Roy, University of California, San Francisco View Media
Draper, shown in the fatbody of a Drosophila melanogaster larva
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The fly fatbody is a nutrient storage and mobilization organ akin to the mammalian liver. The engulfment receptor Draper (green) is located at the cell surface of fatbody cells. Christina McPhee and Eric Baehrecke, University of Massachusetts Medical School View Media
Staphylococcus aureus in the porous coating of a femoral hip stem
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Staphylococcus aureus bacteria (blue) on the porous coating of a femoral hip stem used in hip replacement surgery. Paul Stoodley, The Ohio State University. View Media
Optic nerve astrocytes
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Astrocytes in the cross section of a human optic nerve head Tom Deerinck and Keunyoung (“Christine”) Kim, NCMIR View Media
Proteins related to myotonic dystrophy
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Myotonic dystrophy is thought to be caused by the binding of a protein called Mbnl1 to abnormal RNA repeats. Manuel Ares, University of California, Santa Cruz View Media
Golgi theories
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Two models for how material passes through the Golgi apparatus: the vesicular shuttle model and the cisternae maturation model. Judith Stoffer View Media
Human embryonic stem cells on feeder cells
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The nuclei stained green highlight human embryonic stem cells grown under controlled conditions in a laboratory. Blue represents the DNA of surrounding, supportive feeder cells. Julie Baker lab, Stanford University School of Medicine, via CIRM View Media
Retinal pigment epithelium derived from human ES cells 02
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This image shows a layer of retinal pigment epithelium cells derived from human embryonic stem cells, highlighting the nuclei (red) and cell surfaces (green). David Buckholz and Sherry Hikita, University of California, Santa Barbara, via CIRM View Media
Mosaicism in C. elegans (Black Background)
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In the worm C. elegans, double-stranded RNA made in neurons can silence matching genes in a variety of cell types through the transport of RNA between cells. Snusha Ravikumar, Ph.D., University of Maryland, College Park, and Antony M. Jose, Ph.D., University of Maryland, College Park View Media
Body toxins
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Body organs such as the liver and kidneys process chemicals and toxins. These "target" organs are susceptible to damage caused by these substances. Crabtree + Company View Media
Dicty fruit
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Dictyostelium discoideum is a microscopic amoeba. A group of 100,000 form a mound as big as a grain of sand. Featured in The New Genetics. View Media
Motion in the brain
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Amid a network of blood vessels and star-shaped support cells, neurons in the brain signal each other. The mists of color show the flow of important molecules like glucose and oxygen. Kim Hager and Neal Prakash, University of California, Los Angeles View Media
