Switch to Gallery View

Image and Video Gallery

This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

G switch (with labels and stages)

2538

The G switch allows our bodies to respond rapidly to hormones. G proteins act like relay batons to pass messages from circulating hormones into cells. Crabtree + Company View Media

Ribbon diagram of a cefotaxime-CCD-1 complex

6766

CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media

Electrostatic map of human spermine synthase

3658

From PDB entry 3c6k, Crystal structure of human spermine synthase in complex with spermidine and 5-methylthioadenosine. Emil Alexov, Clemson University View Media

Serum albumin structure 2

3745

Serum albumin (SA) is the most abundant protein in the blood plasma of mammals. SA has a characteristic heart-shape structure and is a highly versatile protein. Wladek Minor, University of Virginia View Media

Movie of the 19S proteasome subunit processing a protein substrate

3764

The proteasome is a critical multiprotein complex in the cell that breaks down and recycles proteins that have become damaged or are no longer needed. Andreas Martin, HHMI View Media

Molecules blocking Huntington's protein production

2600

The molecules that glow blue in these cultured cells prevent the expression of the mutant proteins that cause Huntington's disease. Jiaxin Hu, David W. Dodd and Robert H. E. Hudson, UT Southwestern Medical Center View Media

Disease-susceptible Arabidopsis leaf

2782

This is a magnified view of an Arabidopsis thaliana leaf after several days of infection with the pathogen Hyaloperonospora arabidopsidis. Jeff Dangl, University of North Carolina, Chapel Hill View Media

Protein involved in cell division from Mycoplasma pneumoniae

2377

Model of a protein involved in cell division from Mycoplasma pneumoniae. This model, based on X-ray crystallography, revealed a structural domain not seen before. Berkeley Structural Genomics Center, PSI View Media

Seeing signaling protein activation in cells 03

2453

Cdc42, a member of the Rho family of small guanosine triphosphatase (GTPase) proteins, regulates multiple cell functions, including motility, proliferation, apoptosis, and cell morphology. Klaus Hahn, University of North Carolina, Chapel Hill Medical School View Media

RNase A (1)

2398

A crystal of RNase A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Dengue virus membrane protein structure

3758

Dengue virus is a mosquito-borne illness that infects millions of people in the tropics and subtropics each year. Like many viruses, dengue is enclosed by a protective membrane. Hong Zhou, UCLA View Media

VDAC video 03

2572

This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media

ARTS triggers apoptosis

2432

Cell showing overproduction of the ARTS protein (red). ARTS triggers apoptosis, as shown by the activation of caspase-3 (green) a key tool in the cell's destruction. The nucleus is shown in blue. Hermann Steller, Rockefeller University View Media

Shiga toxin

6997

E. coli bacteria normally live harmlessly in our intestines, but some cause disease by making toxins. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Transient receptor potential channel TRPV5

6577

A 3D reconstruction of a transient receptor potential channel called TRPV5 that was created based on cryo-electron microscopy images. Vera Moiseenkova-Bell, University of Pennsylvania. View Media

Isolated Planarian Pharynx

3593

The feeding tube, or pharynx, of a planarian worm with cilia shown in red and muscle fibers shown in green View Media

Life of an AIDS virus (with labels and stages)

2515

HIV is a retrovirus, a type of virus that carries its genetic material not as DNA but as RNA. Crabtree + Company View Media

Cas4 nuclease protein structure

3720

This wreath represents the molecular structure of a protein, Cas4, which is part of a system, known as CRISPR, that bacteria use to protect themselves against viral invaders. Fred Dyda, NIDDK View Media

Beaded bacteriophage

2305

This sculpture made of purple and clear glass beads depicts bacteriophage Phi174, a virus that infects bacteria. It rests on a surface that portrays an adaptive landscape, a conceptual visualization. Holly Wichman, University of Idaho. (Surface by A. Johnston; photo by J. Palmersheim) View Media

Cytochrome structure with anticancer drug

3326

This image shows the structure of the CYP17A1 enzyme (ribbons colored from blue N-terminus to red C-terminus), with the associated heme colored black. Emily Scott, University of Kansas View Media

Bacterial alpha amylase

2401

A crystal of bacterial alpha amylase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Cell Nucleus and Lipid Droplets

6547

A cell nucleus (blue) surrounded by lipid droplets (yellow). James Olzmann, University of California, Berkeley View Media

Protein map

2423

Network diagram showing a map of protein-protein interactions in a yeast (Saccharomyces cerevisiae) cell. This cluster includes 78 percent of the proteins in the yeast proteome. Hawoong Jeong, KAIST, Korea View Media

Himastatin, 360-degree view

6851

A 360-degree view of the molecule himastatin, which was first isolated from the bacterium Streptomyces himastatinicus. Himastatin shows antibiotic activity. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media

Network Map

2735

This network map shows the overlap (green) between the long QT syndrome (yellow) and epilepsy (blue) protein-interaction neighborhoods located within the human interactome. Seth Berger, Mount Sinai School of Medicine View Media

Zika virus

6998

Zika virus is shown in cross section at center left. On the outside, it includes envelope protein (red) and membrane protein (magenta) embedded in a lipid membrane (light purple). Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Section of an electron density map

2354

Electron density maps such as this one are generated from the diffraction patterns of X-rays passing through protein crystals. The Southeast Collaboratory for Structural Genomics View Media

Seeing signaling protein activation in cells 01

2451

Cdc42, a member of the Rho family of small guanosine triphosphatase (GTPase) proteins, regulates multiple cell functions, including motility, proliferation, apoptosis, and cell morphology. Klaus Hahn, University of North Carolina, Chapel Hill Medical School View Media

Nuclear Lamina

6572

The 3D single-molecule super-resolution reconstruction of the entire nuclear lamina in a HeLa cell was acquired using the TILT3D platform. Anna-Karin Gustavsson, Ph.D. View Media

Magnesium transporter protein from E. faecalis

2345

Structure of a magnesium transporter protein from an antibiotic-resistant bacterium (Enterococcus faecalis) found in the human gut. New York Structural GenomiX Consortium View Media

Protein folding video

3391

Proteins are long chains of amino acids. Each protein has a unique amino acid sequence. It is still a mystery how a protein folds into the proper shape based on its sequence. Theoretical and Computational Biophysics Group View Media

H1N1 Influenza Virus

6355

CellPack image of the H1N1 influenza virus, with hemagglutinin and neuraminidase glycoproteins in green and red, respectively, on the outer envelope (white); matrix protein in gray, and ribonucleoprot Dr. Rommie Amaro, University of California, San Diego View Media

RNA Polymerase II

2484

NIGMS-funded researchers led by Roger Kornberg solved the structure of RNA polymerase II. David Bushnell, Ken Westover and Roger Kornberg, Stanford University View Media

Histones in chromatin

2560

Histone proteins loop together with double-stranded DNA to form a structure that resembles beads on a string. Crabtree + Company View Media

Structure of Glutamate Dehydrogenase

3421

Some children are born with a mutation in a regulatory site on this enzyme that causes them to over-secrete insulin when they consume protein. Judy Coyle, Donald Danforth Plant Science Center View Media

Sphingolipid S1P1 receptor

3362

The receptor is shown bound to an antagonist, ML056. Raymond Stevens, The Scripps Research Institute View Media

Sortase b from B. anthracis

2386

Structure of sortase b from the bacterium B. anthracis, which causes anthrax. Sortase b is an enzyme used to rob red blood cells of iron, which the bacteria need to survive. Midwest Center for Structural Genomics, PSI View Media

Protein crystals

1060

Structural biologists create crystals of proteins, shown here, as a first step in a process called X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Ribosome illustration from PDB

5780

Ribosomes are complex machines made up of more than 50 proteins and three or four strands of genetic material called ribosomal RNA (rRNA). From PDB’s Molecule of the Month collection (direct link: http://pdb101.rcsb.org/motm/121) Molecule of the Month illustrations are available under a CC-BY-4.0 license. Attribution should be given to David S. Goodsell and the RCSB PDB. View Media

Kinesin moves cellular cargo

3491

A protein called kinesin (blue) is in charge of moving cargo around inside cells and helping them divide. Charles Sindelar, Yale University View Media

A molecular switch strips transcription factor from DNA

3729

In this video, Rice University scientists used molecular modeling with a mathematical algorithm called AWSEM (for associative memory, water-mediated, structure and energy model) and structural data to Davit Potoyan and Peter Wolynes View Media

Trajectories of labeled cell receptors

2801

Trajectories of single molecule labeled cell surface receptors. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View Media

Structure of a key antigen protein involved with Hepatitis C Virus infection

5866

A three-dimensional representation of the structure of E2, a key antigen protein involved with hepatitis C virus infection. Mansun Law Associate Professor Department of Immunolgy and Microbial Science The Scripps Research Institute View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 7

3419

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Enzymes convert subtrates into products

2521

Enzymes convert substrates into products very quickly. See image 2522 for a labeled version of this illustration. Featured in The Chemistry of Health. Crabtree + Company View Media

Space-filling model of a cefotaxime-CCD-1 complex

6767

CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media

Brains of sleep-deprived and well-rested fruit flies

3490

On top, the brain of a sleep-deprived fly glows orange because of Bruchpilot, a communication protein between brain cells. These bright orange brain areas are associated with learning. Chiara Cirelli, University of Wisconsin-Madison View Media

Life of an AIDS virus

2513

HIV is a retrovirus, a type of virus that carries its genetic material not as DNA but as RNA. Crabtree + Company View Media

Bovine trypsin

2408

A crystal of bovine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Self-organizing proteins

2771

Under the microscope, an E. coli cell lights up like a fireball. Each bright dot marks a surface protein that tells the bacteria to move toward or away from nearby food and toxins. View Media