Image and Video Gallery

This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Dose response curves

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Dose-response curves determine how much of a drug (X-axis) causes a particular effect, or a side effect, in the body (Y-axis). Featured in Medicines By Design. Crabtree + Company View Media

Network Map

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This network map shows the overlap (green) between the long QT syndrome (yellow) and epilepsy (blue) protein-interaction neighborhoods located within the human interactome. Seth Berger, Mount Sinai School of Medicine View Media

See how immune cell acid destroys bacterial proteins

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This animation shows the effect of exposure to hypochlorous acid, which is found in certain types of immune cells, on bacterial proteins. American Chemistry Council View Media

Nucleolus subcompartments spontaneously self-assemble 2

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The nucleolus is a small but very important protein complex located in the cell's nucleus. Nilesh Vaidya, Princeton University View Media

Genetically identical mycobacteria respond differently to antibiotic 1

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Antibiotic resistance in microbes is a serious health concern. So researchers have turned their attention to how bacteria undo the action of some antibiotics. Bree Aldridge, Tufts University View Media

Precisely Delivering Chemical Cargo to Cells

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Moving protein or other molecules to specific cells to treat or examine them has been a major biological challenge. Nature Nanotechnology View Media

Ribbon diagram of a cefotaxime-CCD-1 complex

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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media

Nucleolus subcompartments spontaneously self-assemble 1

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The nucleolus is a small but very important protein complex located in the cell's nucleus. Nilesh Vaidya, Princeton University View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 4

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Genetically identical mycobacteria respond differently to antibiotic 2

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Antibiotic-surviving bacteria

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Colonies of bacteria growing despite high concentrations of antibiotics. These colonies are visible both by eye, as seen on the left, and by bioluminescence imaging, as seen on the right. Paul Stoodley, The Ohio State University. View Media

Yeast cells responding to a glucose shortage

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These yeast cells were exposed to a glucose (sugar) shortage. Mike Henne, University of Texas Southwestern Medical Center. View Media

Kinases (with labels)

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Kinases are enzymes that add phosphate groups (red-yellow structures) to proteins (green), assigning the proteins a code. Crabtree + Company View Media

Human opioid receptor structure superimposed on poppy

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Opioid receptors on the surfaces of brain cells are involved in pleasure, pain, addiction, depression, psychosis, and other conditions. Raymond Stevens, The Scripps Research Institute View Media

Diversity oriented synthesis: generating skeletal diversity using folding processes

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This 1 1/2-minute video animation was produced for chemical biologist Stuart Schreiber's lab page. The animation shows how diverse chemical structures can be produced in the lab. Eric Keller View Media

ATP synthase (with labels)

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The world's smallest motor, ATP synthase, generates energy for the cell. See image 2517 for an unlabeled version of this illustration. Crabtree + Company View Media

Aspirin

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Acetylsalicylate (bottom) is the aspirin of today. Crabtree + Company View Media

Enzyme reaction

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Enzymes speed up chemical reactions by reducing the amount of energy needed for the reactions. NIGMS View Media

Ciclo circadiano de un adolescente típico

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Los ritmos circadianos son cambios físicos, mentales y conductuales que siguen un ciclo de 24 horas. NIGMS View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 3

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

A Bacillus subtilis biofilm grown in a Petri dish

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Bacterial biofilms are tightly knit communities of bacterial cells growing on, for example, solid surfaces, such as in water pipes or on teeth. Gürol Süel, UCSD View Media

Chang Shan

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For thousands of years, Chinese herbalists have treated malaria using Chang Shan, a root extract from a type of hydrangea that grows in Tibet and Nepal. Paul Schimmel Lab, Scripps Research Institute View Media

Plastic-eating enzymes

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PETase enzyme degrades polyester plastic (polyethylene terephthalate, or PET) into monohydroxyethyl terephthalate (MHET). Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Prion protein fibrils 1

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Recombinant proteins such as the prion protein shown here are often used to model how proteins misfold and sometimes polymerize in neurodegenerative disorders. This prion protein was expressed in E. Ken Pekoc (public affairs officer) and Julie Marquardt, NIAID/ Rocky Mountain Laboratories View Media

Molecular view of glutamatergic synapse

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This illustration highlights spherical pre-synaptic vesicles that carry the neurotransmitter glutamate. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Aspirin (with labels)

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Acetylsalicylate (bottom) is the aspirin of today. Crabtree + Company View Media

Independence Day

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This graphic that resembles a firework was created from a picture of a fruit fly spermatid. Sigi Benjamin-Hong, Rockefeller University View Media

Fruit fly brain responds to adipokines

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Drosophila adult brain showing that an adipokine (fat hormone) generates a response from neurons (aqua) and regulates insulin-producing neurons (red).
Akhila Rajan, Fred Hutchinson Cancer Center View Media

Protein formation

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Proteins are 3D structures made up of smaller units. DNA is transcribed to RNA, which in turn is translated into amino acids. NIGMS, with the folded protein illustration adapted from Jane Richardson, Duke University Medical Center View Media

Dynein moving along microtubules

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Dynein (green) is a motor protein that “walks” along microtubules (red, part of the cytoskeleton) and carries its cargo along with it. This video was captured through fluorescence microscopy. Morgan DeSantis, University of Michigan. View Media

Kinases

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Kinases are enzymes that add phosphate groups (red-yellow structures) to proteins (green), assigning the proteins a code. Crabtree + Company View Media

Glucose and sucrose

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Glucose (top) and sucrose (bottom) are sugars made of carbon, hydrogen, and oxygen atoms. Carbohydrates include simple sugars like these and are the main source of energy for the human body. Crabtree + Company View Media

Glycan arrays

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The signal is obtained by allowing proteins in human serum to interact with glycan (polysaccharide) arrays. The arrays are shown in replicate so the pattern is clear. Ola Blixt, Scripps Research Institute View Media

Cytochrome structure with anticancer drug

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This image shows the structure of the CYP17A1 enzyme (ribbons colored from blue N-terminus to red C-terminus), with the associated heme colored black. Emily Scott, University of Kansas View Media

Bioluminescent imaging in adult zebrafish - lateral and overhead view

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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View Media

Bottles of warfarin

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In 2007, the FDA modified warfarin's label to indicate that genetic makeup may affect patient response to the drug. The widely used blood thinner is sold under the brand name Coumadin®. Alisa Machalek, NIGMS/NIH View Media

In vitro assembly of a cell-signaling pathway

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T cells are white blood cells that are important in defending the body against bacteria, viruses and other pathogens. Xiaolei Su, HHMI Whitman Center of the Marine Biological Laboratory View Media

Los ritmos circadianos y el núcleo supraquiasmático

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Los ritmos circadianos son cambios físicos, mentales y de comportamiento que siguen un ciclo de 24 horas. NIGMS View Media

Kinesin moves cellular cargo

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A protein called kinesin (blue) is in charge of moving cargo around inside cells and helping them divide. Charles Sindelar, Yale University View Media

Bacillus anthracis being killed

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Bacillus anthracis (anthrax) cells being killed by a fluorescent trans-translation inhibitor, which disrupts bacterial protein synthesis. Kenneth Keiler, Penn State University View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 7

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Plasma membrane

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The plasma membrane is a cell's protective barrier. See image 2524 for a labeled version of this illustration. Featured in The Chemistry of Health. Crabtree + Company View Media

Serratezomine A

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A 3-D model of the alkaloid serratezomine A shows the molecule's complex ring structure. View Media

Movie of in vitro assembly of a cell-signaling pathway

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T cells are white blood cells that are important in defending the body against bacteria, viruses and other pathogens. Xiaolei Su, HHMI Whitman Center of the Marine Biological Laboratory View Media

Anti-tumor drug ecteinascidin 743 (ET-743), structure without hydrogens 04

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

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