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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Transmission electron microscopy of coronary artery wall with elastin-rich ECM pseudocolored in light brown

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Elastin is a fibrous protein in the extracellular matrix (ECM). It is abundant in artery walls like the one shown here. As its name indicates, elastin confers elasticity. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Cone snail shell

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A shell from the venomous cone snail Conus omaria, which lives in the Pacific and Indian oceans and eats other snails. Kerry Matz, University of Utah View Media

HeLa cells

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Multiphoton fluorescence image of HeLa cells stained with the actin binding toxin phalloidin (red), microtubules (cyan) and cell nuclei (blue). Nikon RTS2000MP custom laser scanning microscope. National Center for Microscopy and Imaging Research (NCMIR) View Media

Bacterial cells migrating through the tissues of the squid light organ

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Vibrio fischeri cells (~ 2 mm), labeled with green fluorescent protein (GFP), passing through a very narrow bottleneck in the tissues (red) of the Hawaiian bobtail squid, Euprymna scolope Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media

Bioluminescence in a Tube

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Details about the basic biology and chemistry of the ingredients that produce bioluminescence are allowing scientists to harness it as an imaging tool. Credit: Nathan Shaner, Scintillon Institute. Nathan Shaner, Scintillon Institute View Media

Fruit fly ovarioles

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Three fruit fly (Drosophila melanogaster) ovarioles (yellow, blue, and magenta) with egg cells visible inside them. Ovarioles are tubes in the reproductive systems of female insects. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View Media

Bence Jones protein MLE

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A crystal of Bence Jones protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Salivary gland in the developing fruit fly

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For fruit flies, the salivary gland is used to secrete materials for making the pupal case, the protective enclosure in which a larva transforms into an adult fly. Richard Fehon, University of Chicago View Media

Ribbon diagram of a cefotaxime-CCD-1 complex

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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media

CRISPR Illustration Frame 1

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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. This is the first frame in a series of four. National Institute of General Medical Sciences. View Media

DNase

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Crystals of DNase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Endoplasmic reticulum abnormalities 2

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Human cells with the gene that codes for the protein FIT2 deleted. After an experimental intervention, they are expressing a nonfunctional version of FIT2, shown in green. Michel Becuwe, Harvard University. View Media

Finding one bug

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A nanometer-sized biosensor can detect a single deadly bacterium in tainted ground beef. How? Weihong Tan, University of Florida in Gainesville View Media

Yeast cells with accumulated cell wall material

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Yeast cells that abnormally accumulate cell wall material (blue) at their ends and, when preparing to divide, in their middles. This image was captured using wide-field microscopy with deconvolution. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media

Dividing cell

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As this cell was undergoing cell division, it was imaged with two microscopy techniques: differential interference contrast (DIC) and confocal. The DIC view appears in blue and shows the entire cell. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media

Confocal microscopy of perineuronal nets in the brain 1

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The photo shows a confocal microscopy image of perineuronal nets (PNNs), which are specialized extracellular matrix (ECM) structures in the brain. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Human blood cells with Borrelia hermsii, a bacterium that causes relapsing fever

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Relapsing fever is caused by a bacterium and transmitted by certain soft-bodied ticks or body lice. The disease is seldom fatal in humans, but it can be very serious and prolonged. NIAID View Media

Dynamic cryo-EM model of the human transcription preinitiation complex

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Gene transcription is a process by which information encoded in DNA is transcribed into RNA. Eva Nogales, Berkeley Lab View Media

Self-organizing proteins

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Under the microscope, an E. coli cell lights up like a fireball. Each bright dot marks a surface protein that tells the bacteria to move toward or away from nearby food and toxins. View Media

C. elegans showing internal structures

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An image of Caenorhabditis elegans, a tiny roundworm, showing internal structures including the intestine, pharynx, and body wall muscle. C. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media

Bioluminescent imaging in adult zebrafish - lateral view

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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View Media

Nano-rainbow

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These vials may look like they're filled with colored water, but they really contain nanocrystals reflecting different colors under ultraviolet light. Shuming Nie, Emory University View Media

V. Cholerae Biofilm

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Industrious V. cholerae bacteria (yellow) tend to thrive in denser biofilms (left) while moochers (red) thrive in weaker biofilms (right). View Media

Activated mast cell surface

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A scanning electron microscope image of an activated mast cell. This image illustrates the interesting topography of the cell membrane, which is populated with receptors. Bridget Wilson, University of New Mexico View Media

Pores on the surface of the Hawaiian bobtail squid light organ

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The light organ (~0.5 mm across) of a juvenile Hawaiian bobtail squid, Euprymna scolopes, stained blue. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media

Electrode probe on mouse Huntington's muscle cell

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Using an electrode, researchers apply an electrical pulse onto a piece of muscle tissue affected by Huntington's disease. Grigor Varuzhanyan and Andrew A. Voss, California State Polytechnic University View Media

3D image of actin in a cell

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Actin is an essential protein in a cell's skeleton (cytoskeleton). It forms a dense network of thin filaments in the cell. Xiaowei Zhuang, Howard Hughes Medical Institute, Harvard University View Media

HeLa cells

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Multiphoton fluorescence image of cultured HeLa cells with a fluorescent protein targeted to the Golgi apparatus (orange), microtubules (green) and counterstained for DNA (cyan). National Center for Microscopy and Imaging Research (NCMIR) View Media

Folding@Home

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Stanford University scientist Vijay Pande decided to couple the power of computers with the help of the public. Judith Stoffer View Media

Fruit fly egg chamber

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A fruit fly (Drosophila melanogaster) egg chamber with microtubules shown in green and actin filaments shown in red. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View Media

Precisely Delivering Chemical Cargo to Cells

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Moving protein or other molecules to specific cells to treat or examine them has been a major biological challenge. Nature Nanotechnology View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 7

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Snowflake yeast 1

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Multicellular yeast called snowflake yeast that researchers created through many generations of directed evolution from unicellular yeast. William Ratcliff, Georgia Institute of Technology. View Media

Bioluminescent imaging in adult zebrafish - overhead view

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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View Media

NMR spectrometer

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This photo shows a Varian Unity Inova 900 MHz, 21.1 T standard bore magnet Nuclear Magnetic Resonnance (NMR) spectrometer. Center for Eukaryotic Structural Genomics View Media

Multivesicular bodies containing intralumenal vesicles assemble at the vacuole 3

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Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View Media

Petri dish containing C. elegans

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This Petri dish contains microscopic roundworms called Caenorhabditis elegans. Researchers used these particular worms to study how C. H. Robert Horvitz and Dipon Ghosh, Massachusetts Institute of Technology. View Media

Heart rates time series image

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These time series show the heart rates of four different individuals. Madalena Costa and Ary Goldberger, Beth Israel Deaconess Medical Center View Media

Brain showing hallmarks of Alzheimer's disease

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Along with blood vessels (red) and nerve cells (green), this mouse brain shows abnormal protein clumps known as plaques (blue). Alvin Gogineni, Genentech View Media

Color coding of the Drosophila brain - image

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This image results from a research project to visualize which regions of the adult fruit fly (Drosophila) brain derive from each neural stem cell. Yong Wan from Charles Hansen’s lab, University of Utah. Data preparation and visualization by Masayoshi Ito in the lab of Kei Ito, University of Tokyo. View Media

Cryo-electron tomography of a Caulobacter bacterium

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3D image of Caulobacter bacterium with various components highlighted: cell membranes (red and blue), protein shell (green), protein factories known as ribosomes (yellow), and storage granules Peter Dahlberg, Stanford University. View Media

Mapping disease spread

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How far and fast an infectious disease spreads across a community depends on many factors, including transportation. These U.S. David Chrest, RTI International View Media

Protein purification robot

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Irina Dementieva, a biochemist, and Youngchang Kim, a biophysicist and crystallographer, work with the first robot of its type in the U.S. to automate protein purification. Midwest Center for Structural Genomics View Media

Human embryonic stem cells on feeder cells

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This fluorescent microscope image shows human embryonic stem cells whose nuclei are stained green. Blue staining shows the surrounding supportive feeder cells. Michael Longaker lab, Stanford University School of Medicine, via CIRM View Media

Fly cells

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If a picture is worth a thousand words, what's a movie worth? Denise Montell, Johns Hopkins University School of Medicine View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 6

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Cytonemes in developing fruit fly cells

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Scientists have long known that multicellular organisms use biological molecules produced by one cell and sensed by another to transmit messages that, for instance, guide proper development of organs Sougata Roy, University of California, San Francisco View Media

Relapsing fever bacterium (gray) and red blood cells

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Relapsing fever is caused by a bacterium and transmitted by certain soft-bodied ticks or body lice. The disease is seldom fatal in humans, but it can be very serious and prolonged. NIAID View Media

Chromatin in human fibroblast

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The nucleus of a human fibroblast cell with chromatin—a substance made up of DNA and proteins—shown in various colors. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media

Tiny points of light in a quantum dot

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This fingertip-shaped group of lights is a microscopic crystal called a quantum dot. About 10,000 times thinner than a sheet of paper, the dot radiates brilliant colors under ultraviolet light. Sandra Rosenthal and James McBride, Vanderbilt University, and Stephen Pennycook, Oak Ridge National Laboratory View Media