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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Electrostatic map of the adeno-associated virus with scale
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The new highly efficient parallelized DelPhi software was used to calculate the potential map distribution of an entire virus, the adeno-associated virus, which is made up of more than 484,000 atoms. Emil Alexov, Clemson University View Media
Electrode probe on mouse Huntington's muscle cell
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Using an electrode, researchers apply an electrical pulse onto a piece of muscle tissue affected by Huntington's disease. Grigor Varuzhanyan and Andrew A. Voss, California State Polytechnic University View Media
CRISPR illustration
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media
Multinucleated cancer cell
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A cancer cell with three nuclei, shown in turquoise. The abnormal number of nuclei indicates that the cell failed to go through cell division, probably more than once. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media
Microtubules in hippocampal neurons
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Microtubules (magenta) in neurons of the hippocampus, a part of the brain involved in learning and memory. Microtubules are strong, hollow fibers that provide structural support to cells. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media
Fluorescence in situ hybridization (FISH) in mouse ES cells shows DNA interactions
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Researchers used fluorescence in situ hybridization (FISH) to confirm the presence of long range DNA-DNA interactions in mouse embryonic stem cells. Kathrin Plath, University of California, Los Angeles View Media
Chromium X-ray source
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In the determination of protein structures by X-ray crystallography, this unique soft (l = 2.29Å) X-ray source is used to collect anomalous scattering data from protein crystals containing light atoms The Southeast Collaboratory for Structural Genomics View Media
Dense tubular matrices in the peripheral endoplasmic reticulum (ER) 1
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Superresolution microscopy work on endoplasmic reticulum (ER) in the peripheral areas of the cell showing details of the structure and arrangement in a complex web of tubes. Jennifer Lippincott-Schwartz, Howard Hughes Medical Institute Janelia Research Campus, Virginia View Media
Protein folding video
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Proteins are long chains of amino acids. Each protein has a unique amino acid sequence. It is still a mystery how a protein folds into the proper shape based on its sequence. Theoretical and Computational Biophysics Group View Media
HeLa cells
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Scanning electron micrograph of just-divided HeLa cells. Zeiss Merlin HR-SEM. National Center for Microscopy and Imaging Research View Media
Fruit fly egg chamber
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A fruit fly (Drosophila melanogaster) egg chamber with microtubules shown in green and actin filaments shown in red. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View Media
Hawaiian bobtail squid
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An adult Hawaiian bobtail squid, Euprymna scolopes, swimming next to a submerged hand. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media
RSV-Infected Cell
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Viral RNA (red) in an RSV-infected cell. Eric Alonas and Philip Santangelo, Georgia Institute of Technology and Emory University View Media
Tracking embryonic zebrafish cells
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To better understand cell movements in developing embryos, researchers isolated cells from early zebrafish embryos and grew them as clusters. Liliana Solnica-Krezel, Washington University School of Medicine in St. Louis. View Media
Bioluminescence in a Tube
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Details about the basic biology and chemistry of the ingredients that produce bioluminescence are allowing scientists to harness it as an imaging tool. Credit: Nathan Shaner, Scintillon Institute. Nathan Shaner, Scintillon Institute View Media
Podocytes from a chronically diseased kidney
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This scanning electron microscope (SEM) image shows podocytes--cells in the kidney that play a vital role in filtering waste from the bloodstream--from a patient with chronic kidney disease. Olga Troyanskaya, Princeton University and Matthias Kretzler, University of Michigan View Media
Microtubules and tau aggregates
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Microtubules (magenta) and tau protein (light blue) in a cell model of tauopathy. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media
Staphylococcus aureus aggregating upon contact with synovial fluid
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Staphylococcus aureus bacteria (green) grouping together upon contact with synovial fluid—a viscous substance found in joints. Paul Stoodley, The Ohio State University. View Media
Chromatin in human fibroblast
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The nucleus of a human fibroblast cell with chromatin—a substance made up of DNA and proteins—shown in various colors. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media
Computer sketch of bird-and-flower DNA origami
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A computer-generated sketch of a DNA origami folded into a flower-and-bird structure. See also related image 3690. Hao Yan, Arizona State University View Media
Chromatin in human tenocyte
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The nucleus of a degenerating human tendon cell, also known as a tenocyte. It has been color-coded based on the density of chromatin—a substance made up of DNA and proteins. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media
Math from the heart
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Watch a cell ripple toward a beam of light that turns on a movement-related protein. View Media
Human embryonic stem cells on feeder cells
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This fluorescent microscope image shows human embryonic stem cells whose nuclei are stained green. Blue staining shows the surrounding supportive feeder cells. Michael Longaker lab, Stanford University School of Medicine, via CIRM View Media
Fungal lipase (2)
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Crystals of fungal lipase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Cytoscape network diagram 1
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Molecular biologists are increasingly relying on bioinformatics software to visualize molecular interaction networks and to integrate these networks with data such as gene expression profiles. Keiichiro Ono, Trey Ideker lab, University of California, San Diego View Media
Introduction to Genome Editing Using CRISPR/Cas9
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Genome editing using CRISPR/Cas9 is a rapidly expanding field of scientific research with emerging applications in disease treatment, medical therapeutics and bioenergy, just to name a few. Janet Iwasa View Media
Dengue virus membrane protein structure
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Dengue virus is a mosquito-borne illness that infects millions of people in the tropics and subtropics each year. Like many viruses, dengue is enclosed by a protective membrane. Hong Zhou, UCLA View Media
Lysosomes and microtubules
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Lysosomes (yellow) and detyrosinated microtubules (light blue). Lysosomes are bubblelike organelles that take in molecules and use enzymes to break them down. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media
Modeling disease spread
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What looks like a Native American dream catcher is really a network of social interactions within a community. Stephen Eubank, University of Virginia Biocomplexity Institute (formerly Virginia Bioinformatics Institute) View Media
C. elegans showing internal structures
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An image of Caenorhabditis elegans, a tiny roundworm, showing internal structures including the intestine, pharynx, and body wall muscle. C. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media
Retinal pigment epithelium derived from human ES cells
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This color-enhanced image is a scanning electron microscope image of retinal pigment epithelial (RPE) cells derived from human embryonic stem cells. David Hinton lab, University of Southern California, via CIRM View Media
CRISPR Illustration Frame 2
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media
Mouse brain slice showing nerve cells
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A 20-µm thick section of mouse midbrain. The nerve cells are transparent and weren’t stained. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media
A molecular interaction network in yeast 2
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The image visualizes a part of the yeast molecular interaction network. Keiichiro Ono, UCSD View Media
Self-organizing proteins
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Under the microscope, an E. coli cell lights up like a fireball. Each bright dot marks a surface protein that tells the bacteria to move toward or away from nearby food and toxins. View Media
RNase A (1)
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A crystal of RNase A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Multicolor STORM
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In 2006, scientists developed an optical microscopy technique enabling them to clearly see individual molecules within cells. In 2007, they took the technique, abbreviated STORM, a step further. Xiaowei Zhuang, Harvard University View Media
Mouse brain 2
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A mouse brain that was genetically modified so that subpopulations of its neurons glow. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View Media
Cell-free protein synthesizers
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Both instruments shown were developed by CellFree Sciences of Yokohama, Japan. Center for Eukaryotic Structural Genomics View Media
Transmission electron microscopy showing cross-section of the node of Ranvier
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Nodes of Ranvier are short gaps in the myelin sheath surrounding myelinated nerve cells (axons). Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
Rat Hippocampus
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This image of the hippocampus was taken with an ultra-widefield high-speed multiphoton laser microscope. Tom Deerinck, NCMIR View Media
Honeybee brain
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Insect brains, like the honeybee brain shown here, are very different in shape from human brains. Gene Robinson, University of Illinois at Urbana-Champaign. View Media
Color-coded chromosomes
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By mixing fluorescent dyes like an artist mixes paints, scientists are able to color code individual chromosomes. Anna Jauch, Institute of Human Genetics, Heidelberg, Germany View Media
A Growing Bacterial Biofilm
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A growing Vibrio cholerae (cholera) biofilm. Cholera bacteria form colonies called biofilms that enable them to resist antibiotic therapy within the body and other challenges to their growth. Jing Yan, Ph.D., and Bonnie Bassler, Ph.D., Department of Molecular Biology, Princeton University, Princeton, NJ. View Media
Pig trypsin (3)
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Crystals of porcine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Cell-like compartments emerging from scrambled frog eggs 2
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Cell-like compartments spontaneously emerge from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media
Neutrophil-like cells migrating in a microfluidic chip
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Neutrophil-like cells (blue) in a microfluidic chip preferentially migrating toward LTB4 over fMLP. Caroline Jones, University of Texas at Dallas. View Media
Trigonium diatom
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A Trigonium diatom imaged by a quantitative orientation-independent differential interference contrast (OI-DIC) microscope. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media
Flagellated bacterial cells
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Vibrio fischeri (2 mm in length) is the exclusive symbiotic partner of the Hawaiian bobtail squid, Euprymna scolopes. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media
Yeast cells entering mitosis
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Yeast cells entering mitosis, also known as cell division. The green and magenta dots are two proteins that play important roles in mitosis. They show where the cells will split. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media
