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Lily mitosis 08
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaCRISPR Illustration Frame 5
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. This is the fifthframe in a series of five. View MediaCRISPR Illustration Frame 1
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. This is the first frame in a series of four. National Institute of General Medical Sciences. View MediaPollen grains: male germ cells in plants and a cause of seasonal allergies
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Those of us who get sneezy and itchy-eyed every spring or fall may have pollen grains, like those shown here, to blame. Edna, Gil, and Amit Cukierman, Fox Chase Cancer Center, Philadelphia, Pa. View MediaPlanting roots
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At the root tips of the mustard plant Arabidopsis thaliana (red), two proteins work together to control the uptake of water and nutrients. Philip Benfey, Duke University View MediaMeiosis illustration
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Meiosis is the process whereby a cell reduces its chromosomes from diploid to haploid in creating eggs or sperm. Crabtree + Company View MediaLily mitosis 03
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaGFP sperm
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Fruit fly sperm cells glow bright green when they express the gene for green fluorescent protein (GFP). View MediaNucleolus subcompartments spontaneously self-assemble 4
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What looks a little like distant planets with some mysterious surface features are actually assemblies of proteins normally found in the cell's nucleolus, a small but very important protein complex lo Nilesh Vaidya, Princeton University View MediaHistones in chromatin (with labels)
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Histone proteins loop together with double-stranded DNA to form a structure that resembles beads on a string. Crabtree + Company View MediaFrom DNA to Protein
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Nucleotides in DNA are copied into RNA, where they are read three at a time to encode the amino acids in a protein. Many parts of a protein fold as the amino acids are strung together. Crabtree + Company View MediaPainted chromosomes
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Like a paint-by-numbers picture, painted probes tint individual human chromosomes by targeting specific DNA sequences. Beth A. Sullivan, Duke University View MediaCentral dogma, illustrated (with labels)
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DNA encodes RNA, which encodes protein. DNA is transcribed to make messenger RNA (mRNA). The mRNA sequence (dark red strand) is complementary to the DNA sequence (blue strand). Crabtree + Company View MediaCRISPR Illustration
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaZinc finger
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The structure of a gene-regulating zinc finger protein bound to DNA. Jeremy M. Berg, National Institute of General Medical Sciences View MediaGolden gene chips
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A team of chemists and physicists used nanotechnology and DNA's ability to self-assemble with matching RNA to create a new kind of chip for measuring gene activity. Hao Yan and Yonggang Ke, Arizona State University View MediaNucleotides make up DNA (with labels)
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DNA consists of two long, twisted chains made up of nucleotides. Each nucleotide contains one base, one phosphate molecule, and the sugar molecule deoxyribose. Crabtree + Company View MediaA chromosome goes missing in anaphase
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Anaphase is the critical step during mitosis when sister chromosomes are disjoined and directed to opposite spindle poles, ensuring equal distribution of the genome during cell division. View MediaPrecise development in the fruit fly embryo
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This 2-hour-old fly embryo already has a blueprint for its formation, and the process for following it is so precise that the difference of just a few key molecules can change the plans. Thomas Gregor, Princeton University View MediaXenopus laevis embryos
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Xenopus laevis, the African clawed frog, has long been used as a model organism for studying embryonic development. The frog embryo on the left lacks the developmental factor Sizzled. Michael Klymkowsky, University of Colorado, Boulder View MediaInterphase in Xenopus frog cells
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These images show frog cells in interphase. The cells are Xenopus XL177 cells, which are derived from tadpole epithelial cells. The microtubules are green and the chromosomes are blue. Claire Walczak, who took them while working as a postdoc in the laboratory of Timothy Mitchison. View MediaBottles of warfarin
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In 2007, the FDA modified warfarin's label to indicate that genetic makeup may affect patient response to the drug. The widely used blood thinner is sold under the brand name Coumadin®. Alisa Machalek, NIGMS/NIH View MediaNucleolus subcompartments spontaneously self-assemble 2
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The nucleolus is a small but very important protein complex located in the cell's nucleus. Nilesh Vaidya, Princeton University View Media