Using computers to model basic processes is becoming more prevalent across all areas of scientific research. Modeling can predict information about systems—weather forecasts have been based on computer models for decades—or simulate interactions that increase our understanding of fundamental processes like those within cells. Give us your input on the impact of modeling in biomedical research during a meeting at NIH on December 15 and 16. You can join the discussion remotely through the NIH Videocast Web site. For videocast details, see the Day 1 and Day 2 videocast pages. The meeting is hosted by the Interagency Modeling and Analysis Group (IMAG), which includes program directors from eight government agencies in the United States and Canada. Participants in this year’s meeting, called “IMAG Futures,” will address modeling efforts at five biological scales: population, whole-body, cell-tissue-organ, pathways and networks, and atomic and molecular. For more information, see the meeting agenda.