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June 27, 2011

Archived: NIGMS Cell Repository Now Includes iPS Cell Lines

The HGCR iPS cell lines undergo extensive characterization, including assessment of their capacity to differentiate into specialized cell types. The cell shown here was directed to differentiate into a nerve cell.As we anticipated last year, the NIGMS Human Genetic Cell Repository (HGCR) now offers human induced pluripotent stem cell lines that carry disease gene mutations. The first five lines to be made available were derived from individuals with Huntington’s disease, juvenile onset diabetes, severe combined immunodeficiency disease, muscular dystrophy and spinal muscular atrophy. The repository is developing more cell lines representing other diseases.

The iPS cell lines, along with more than 10,000 others in the repository, are comprehensively characterized to ensure their identity, stability and purity. This quality control makes the repository an excellent resource for researchers who need well-characterized, disease-specific cells.

You can order any of the repository’s cell lines via the HGCR catalog.


About the Author

Judith Greenberg

Judith Greenberg

Before her retirement in October 2020, Judith was the deputy director of NIGMS and the acting director of the Division of Biophysics, Biomedical Technology, and Computational Biosciences. In the past, she also served as the acting director of the Institute and as the director of the former Division of Genetics and Developmental Biology. She led the development of the NIGMS strategic plan issued in 2008 and the development and implementation of the NIGMS strategic plan for training issued in 2011.