You may be interested in the following funding opportunity announcement: Native American Research Centers for Health (NARCH) (PAR-12-182) Purpose: Support partnerships between American Indian/Alaska Native (AI/AN) communities and research-intensive institutions to conduct research and research training to meet the needs of AI/AN communities Letter of intent due date: June 10, 2012 Application due date: July 10, 2012 NIGMS contact: Sheila Caldwell, 301-435-0760

You may be interested in the following reissued funding opportunity announcements: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp) (PA-12-149) Purpose: Request supplemental funds to existing research grants to improve the diversity of the research workforce by supporting and recruiting high school, undergraduate, postbaccalaureate or graduate students and postdoctoral fellows from groups that are underrepresented in health-related research (racial and ethnic groups; individuals with disabilities; and individuals from socially, culturally, economically or educationally disadvantaged backgrounds). See our diversity supplements Web site for additional information. Application due date: Supplement requests may be submitted throughout the year NIGMS contact: Your program director or Marion Zatz, 301-594-3833 Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers (Admin Supp) (PA-12-150) Purpose: Request supplemental funds to existing research grants to support individuals with high potential to re-enter an active research career after an interruption for family responsibilities or other qualifying circumstances. See our supplements for career re-entry Web site for additional information. Application due date: Supplement requests may be submitted throughout the year NIGMS contact: Your program director or Marion Zatz, 301-594-3833

You may be interested in the following NIH Common Fund-related opportunities: Use-Oriented Basic Research: Change Mechanisms of Behavioral Social Interventions (Admin Supp) (PA-12-119) Purpose: Fund administrative supplements to study possible mechanisms of action of behavioral or social interventions Application due date: May 15, 2012 NIH contacts: Lisa Onken, NIDA, 301-443-0107 Melissa Riddle, NIDCR, 301-451-3888 Varda Shoham, NIMH, 301-443-8694 Request for Information (RFI): Challenges and Opportunities in Single Cell Analysis for Biomedical Research (NOT-RM-12-018) Purpose: Provide input to an NIH Common Fund working group charged with identifying challenges and emerging opportunities related to single-cell analysis Response due date: April 12, 2012 Send responses to single_cell@mail.nih.gov

You may be interested in the following recently issued funding opportunity announcements: Collaborations for Macromolecular Interactions in Cells (R01) (RFA-GM-13-004) Purpose: Establish interdisciplinary collaborative projects to advance studies of macromolecular interactions and their relationship to function in cells. Letter of intent due date: May 14, 2012 Application due date: June 14, 2012 NIGMS contacts: Division of Biomedical Technology, Bioinformatics, and Computational Biology Paul Brazhnik, 301-451-6446 Division of Cell Biology and Biophysics James Deatherage and Alexandra Ainsztein, 301-594-0828 Division of Genetics and Developmental Biology Daniel Janes, 301-594-0943 Division of Pharmacology, Physiology, and Biological Chemistry Vernon Anderson, 301-594-3827 Research Networks for Macromolecular Interactions in Cells (U54) (RFA-GM-13-005) Purpose: Establish interdisciplinary collaborative research networks to advance studies of macromolecular interactions and their relationship to function in cells. Letter of intent due date: May 14, 2012 Application due date: June 14, 2012 NIGMS contacts: Division of Biomedical Technology, Bioinformatics, and Computational Biology Paul Brazhnik, 301-451-6446 Division of Cell Biology and Biophysics James Deatherage and Alexandra Ainsztein, 301-594-0828 Division of Genetics and Developmental Biology Daniel Janes, 301-594-0943 Division of Pharmacology, Physiology, and Biological Chemistry Vernon Anderson, 301-594-3827 Small Business Alzheimer's Disease Research (SBIR[R43/R44]) (RFA-OD-12-003) Purpose: Solicit Small Business Innovation Research (SBIR) grant applications in the area of Alzheimer's disease. Letter of intent due date: March 30, 2012 Application due date: April 30, 2012 NIGMS contact: Scott Somers, 301-594-3827 Small Business Alzheimer's Disease Research (STTR[R41/R42]) (RFA-OD-12-004) Purpose: Solicit Small Business Technology Transfer Research (STTR) grant applications in the area of Alzheimer's disease. Letter of intent due date: March 30, 2012 Application due date: April 30, 2012 NIGMS contact: Scott Somers, 301-594-3827

You may be interested in the following recently issued funding opportunity announcements: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp) (PA-12-100) Purpose: Request supplemental funds to existing research grants to meet increased costs that are within the scope of the approved award, but that were unforeseen when the new or renewal application or grant progress report for noncompeting continuation support was submitted. At NIGMS, funds for administrative supplements have always been and will continue to be limited. If you are thinking about submitting an application for an administrative supplement, contact your program director to discuss whether the application is likely to be competitive for funding. Application due date: Dates vary NIGMS contact: Your program director Assays for High Throughput Screening (HTS) to Discover Chemical Probes in the Molecular Libraries Probe Production Centers Network (MLPCN) (X01) (PAR-12-108) Purpose: Form collaborations with the Molecular Libraries Probe Production Centers Network (MLPCN) to implement HTS-ready assays for the discovery and development of small molecule chemical probes Letter of intent due dates: March 16, 2012; July 16, 2012 Application due dates: April 16, 2012; August 15, 2012 NIH contact: Yong Yao, 301-443-6102

You may be interested in the following funding opportunity announcements and NIH requests for information: Funding Opportunity Announcements

• Modeling Social Behavior (R01)
• Competing Revisions for Macromolecular Interactions in Cells (R01)
• Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32)
• PHS 2012-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
• PHS 2012-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
• Resource Access for the Bridging Interventional Development Gaps Program (X01)

NIH Requests for Information

• Request for Information (RFI): Input into the Deliberations of the Advisory Committee to the NIH Director Working Group on Diversity in the Biomedical Research Workforce
• Request for Information (RFI): Input into the Deliberations of the Advisory Committee to the NIH Director Working Group on Data and Informatics

Funding Opportunity Announcements Modeling Social Behavior (R01) (RFA-GM-13-006) Purpose: Develop and test innovative theories and computational, mathematical or engineering approaches to deepen understanding of complex social behavior Letter of intent due date: March 3, 2012 Application due date: April 3, 2012 NIGMS contact: Stephen Marcus, 301-451-6446 Competing Revisions for Macromolecular Interactions in Cells (R01) (RFA-GM-13-003) Purpose: Extend the scope and capabilities of currently funded investigations on macromolecular interactions and their relationship to function in cells Letter of intent due dates: February 26, 2012; September 18, 2012 Application due dates: March 26, 2012; October 18, 2012 NIGMS contact: James Deatherage, 301-594-0828 Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32) (PAR-12-084) Purpose: Prepare predoctoral students for independent research careers in the neurosciences Letter of intent due dates: April 25, 2012; April 25, 2013; April 25, 2014 Application due dates: May 25, 2012; May 25, 2013; May 25, 2014 NIGMS contact: Alison Cole, 301-594-3827 PHS 2012-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44]) (PA-12-088) Purpose: Submit Small Business Innovation Research (SBIR) Phase I, Phase II, Fast-Track and Phase IIB competing renewal grant applications Application due dates: Standard dates apply NIGMS contact: Scott Somers, 301-594-3827 PHS 2012-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42]) (PA-12-089) Purpose: Submit Small Business Technology Transfer (STTR) Phase I, Phase II, Fast-Track and Phase II competing renewal grant applications Application due dates: Standard dates apply NIGMS contact: Scott Somers, 301-594-3827 Resource Access for the Bridging Interventional Development Gaps Program (X01) (PAR-12-092) Purpose: Acquire access to government-funded contract resources needed for the preclinical development of therapeutic agents Application due date: April 3, 2012 NIH contact: Tony Jackson, 301-594-4660 NIH Requests for Information Request for Information (RFI): Input into the Deliberations of the Advisory Committee to the NIH Director Working Group on Diversity in the Biomedical Research Workforce (NOT-OD-12-031) Purpose: Provide input to a working group charged with examining diversity in the biomedical research workforce and providing recommendations on ways to enhance diversity throughout various research career stages, particularly with regard to underrepresented minorities, persons with disabilities and persons from disadvantaged backgrounds Response due date: February 24, 2012 Request for Information (RFI): Input into the Deliberations of the Advisory Committee to the NIH Director Working Group on Data and Informatics (NOT-OD-12-032) Purpose: Provide input to a working group charged with investigating the management, integration and analysis of large biomedical datasets Response due date: March 12, 2012

You may be interested in the following recently issued funding opportunity announcements: Postbaccalaureate Research Education Program (PREP) (R25) (PAR-12-056) Purpose: Prepare recent baccalaureate science graduates from diverse backgrounds for Ph.D. or M.D.-Ph.D. degrees in biomedical and behavioral sciences Application due date: February 24, 2012 NIGMS contact: Michael Bender, 301-594-0943 Solicitation of Assays for High Throughput Screening (HTS) to Discover Chemical Probes (R01) (PAR-12-058) and Solicitation of Assays for High Throughput Screening (HTS) to Discover Chemical Probes (R21) (PAR-12-059) Purpose: Form collaborations with an academic, nonprofit or commercial high throughput screening (HTS) facility that has the expertise and experience to implement an HTS-ready assay to develop and discover small-molecule chemical probes Letter of intent due date: 30 days prior to the anticipated application due date Application due date: Standard dates apply NIGMS contact: Miles Fabian, 301-594-3827 Solicitation of Validated Hits for the Discovery of in vivo Chemical Probes (R01) (PAR-12-060) Purpose: Discover and develop novel in vivo chemical probes for potential use in studying diseases Letter of intent due date: 30 days prior to the anticipated application due date Application due date: Standard dates apply NIGMS contact: Miles Fabian, 301-594-3827

You may be interested in the following recently issued funding opportunity announcements: New Methods for Understanding the Functional Role of Human DNA Sequence Variants in Complex Phenotypes (R01) (RFA-GM-13-002) Purpose: Use experimental and/or computational methods to determine the functional relevance of human DNA sequence variants Letter of intent due date: January 17, 2012 Application due date: February 17, 2012 NIGMS contact: Donna Krasnewich, 301-594-0943 Mentored Research Scientist Development Award in Metabolomics (K01) (RFA-RM-11-017) Purpose: Pursue intensive research training in the field of metabolomics Application due date: January 31, 2012 NIGMS contact: Richard Okita, 301-594-3827 This funding opportunity announcement (FOA) was issued by the NIH Common Fund but will be administered by NIGMS. For other recently issued Common Fund FOAs, including several focused on single cell biology, see the NIH Guide.

You may be interested in this recently reissued funding opportunity announcement: Academic Research Enhancement Award (Parent R15) (PA-12-006) Purpose: Stimulate research at educational institutions that have not been major recipients of NIH support Application due date: Standard dates apply NIGMS contact: Jean Chin, 301-594-0828

Many kids (and adults) learned more about science and technology at the 2-week-long USA Science & Engineering Festival this month in Washington, D.C. The event featured hundreds of activities, including performances, workshops, demonstrations, tours of mobile labs and interactive games. A number of these were hosted by NIH, which was also one of the event sponsors, and most of its components. The festival wrapped up last weekend with a grand finale expo on the National Mall. On Sunday, I helped host the NIGMS booth, where we presented a computer activity called “Supermodels of Science.” It showed how model organisms—from slimy worms to furry mice—help scientists learn more about human health. The kids were most excited about responding to the quiz questions at the end of each segment. They also were very interested in how scientists use GFP to make organisms glow different colors. Other NIH activities included a musical performance by NIH Director Francis Collins; the National Human Genome Research Institute’s “Strawberry DNA Extraction,” a hands-on lab experiment where visitors used a soapy mixture to remove DNA from mashed strawberries; and the National Institute on Deafness and Other Communication Disorders’ “It’s a Noisy Planet,” where staff increased the volume on an iPod to demonstrate dangerous noise levels. The festival’s turnout was excellent—about 500,000 people attended the weekend event. The kids were excited about science and eager to learn, and the volunteer staff members were thrilled to teach them about the research we support. We’ll post the “Supermodels of Science” activity on the NIGMS Web site soon, and you’re welcome to use it in your own educational outreach efforts.