UPDATE: The deadline to respond to this RFI has been extended to October 15. See NOT-GM-24-059 for details.

NIGMS supports National and Regional Resources (NRRs) that provide biomedical researchers with access to mature technologies and Biomedical Technology Optimization and Dissemination (BTOD) Centers that optimize and disseminate late-stage technologies for the research community to use. The NRR-associated mature technologies are ready for researchers’ immediate use without further development. By contrast, the late-stage technologies supported by BTOD Centers require optimization prior to dissemination to the biomedical research community.

NIGMS supports a variety of structural biology research resources, including those funded through the Mature Synchrotron Resources (MSR) program. We’re currently evaluating the MSR program to inform future directions about the structure and operations of the program. As part of this evaluation, we’re seeking input from the extramural community (e.g., principal investigators and key personnel of MSR awards, resource staff, the user community, members of relevant advisory boards, and any other interested parties) on their experiences with and/or opinions on NIGMS-supported synchrotron resources.

NIGMS supports individuals and institutions that foster research training and a strong and diverse biomedical research workforce through a variety of programs at the undergraduate, graduate, and postdoctoral levels. We’re seeking input from trainees (undergraduates, graduate students, postdoctoral scientists), biomedical faculty, and research education program participants (e.g., postbaccalaureates), on initiatives that can help us improve research training, career progression, or the educational environment. NIGMS is especially interested in hearing about trainee-initiated activities—particularly from the trainees themselves—in NIGMS-funded training programs, including U-RISE, MARC, BUILD, PREP, G-RISE, IMSD, Bridges to the Baccalaureate, Bridges to the Doctorate, IRACDA, MOSAIC, basic biomedical T32, and MSTP.

The NIH Common Fund’s Transformative High Resolution Cryo-Electron Microscopy (cryo-EM) program is requesting input from the community in identifying challenges in screening samples for high resolution cryo-EM, an essential step required for data collection at the National Centers for Cryo-EM. We welcome responses from researchers interested in cryo-EM, including those who have not previously worked in the field.

For more details, see the Request for Information (RFI): Screening for High Resolution Cryo-Electron Microscopy (NOT-RM-21-012). Please respond to the email address in the RFI by February 26.