This blog is from the National Institute of General Medical Sciences, one of the National Institutes of Health in the U.S. Department of Health and Human Services. By supporting basic biomedical research and training nationwide, NIGMS lays the foundation for advances in disease diagnosis, treatment, and prevention.

The NIGMS Feedback Loop is intended primarily for current NIGMS grantees, applicants and others in the scientific community who want the latest information on funding opportunities, meetings, resources, and other useful information. As announcements of interest become available, Institute staff will post them here.

Funding Opportunities: COBRE Phase 1 Applications for Women’s Health and Data Sciences Research

September 1, 2021

We’re pleased to announce that we’ve published two notices of special interest (NOSI) calling for applications to PAR-19-313, Centers of Biomedical Research Excellence (COBRE) Phase 1 (P20 Clinical Trial Optional), that focus on research on women’s health (NOT-GM-21-056) and data sciences (NOT-GM-21-062).

These NOSIs highlight the Office of Research on Women's Health's interest in supporting a meritorious application on women's health, and the Office of Data Science Strategy’s interest in supporting a meritorious application on data science relevant to biomedical research. Applications for these NOSIs must be submitted in response to and meet all eligibility criteria of PAR-19-313.

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MOSAIC Program Announcements Reissued; Join Our Webinar September 7

August 18, 2021

UPDATE: The video and slides [PDF] from the webinar are now available.

We’re pleased to share that the Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) funding opportunity announcements (FOAs) have been reissued. MOSAIC, a trans-NIH initiative that NIGMS oversees, has two components: a postdoctoral career transition award (K99/R00), and a cohort-based mentoring and career development program that supports the scholars (UE5 research education cooperative agreement).

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NIGMS to Co-Host ARPA-H Listening Session

July 20, 2021

UPDATE: The videocast of the ARPA-H session on August 4 is now available.

President Biden recently called for the establishment of the Advanced Research Projects Agency for Health (ARPA-H) to improve our capabilities to speed research that can improve the health of all Americans. The proposed mission of ARPA-H could include investments in breakthrough technologies and broadly applicable platforms, resources, and solutions that can’t be readily accomplished through traditional research or commercial activity. Such innovations could transform important areas of medicine and health for the benefit of all patients.

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New Research on Interventions R01 Funding Announcement and Upcoming Webinar

July 13, 2021

UPDATE: The video from the Interventions webinar is now available.

NIGMS has reissued its funding opportunity announcement (FOA) for Research on Interventions that Promote the Careers of Individuals in the Biomedical Research Enterprise (R01) (PAR-21-269). In line with a key mission area of the Institute—ensuring the vitality and continued productivity of the research enterprise—the FOA encourages studies on interventions aimed to enhance research-oriented individuals’ interest, motivation, persistence, and preparedness for careers in the biomedical research workforce. Potential intervention focus areas include, but are not limited to, networking and mentoring, institutional climate, harassment, and structural racism and discrimination.

The new FOA no longer includes research designed solely to inform interventions; applicants must also conduct and test an intervention. Proposals must test the effectiveness of an intervention using robust experimental designs, such as randomized control trial approaches, case controls, matched pair design, or other designs appropriate to perform rigorous research on effective interventions aiming to increase success in the biomedical research workforce.

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Updated Council Review and Oversight Policy for Well-Funded Laboratories

July 2, 2021

NIGMS staff members always closely examine each principal investigator’s (PI’s) other research support when making funding recommendations and awards. In addition, the Institute has several policies to ensure a diversified portfolio of grants. At the May 20, 2021, NAGMS Advisory Council meeting, councilors approved our updated NIGMS guidelines for funding investigators with substantial other research support. Informally, this was known as our $750K policy. What’s the policy, and why are we changing it now? 

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Webinar for Postdoctoral Research Associate Training (PRAT) Program Applicants

June 1, 2021

We’re hosting a webinar for students and fellows interested in the Postdoctoral Research Associate Training (PRAT) program for the October 4, 2021, receipt date:

Tuesday, June 22, 2:00-3:00 p.m. ET

PRAT is a competitive 3-year fellowship program that prepares trainees for leadership positions in biomedical careers. Training includes a mentored laboratory research experience and intensive career and leadership development activities. PRAT fellows conduct research in laboratories in the NIH Intramural Research Program (IRP) in basic biomedical research areas within the NIGMS mission. These areas include, but are not limited to, biological chemistry, biophysics, bioinformatics, cellular and molecular biology, computational biosciences, developmental biology, genetics, immunology, neuroscience, pharmacology, physiology, and technology development.

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