The NIGMS National Centers for Cryoelectron Microscopy (NCCEM, PAR-23-118) provide the biomedical research community with access to state-of-the-art equipment, technical support, and training for the production and analysis of high-resolution cryoelectron microscopy (cryoEM) data.

The Centers offer equal-opportunity nationwide access to their services through an open application process. Detailed information on offerings and applying for access can be found on cryoemcenters.org.

For program information, contact​​:
Paula Flicker, Ph.D. and Veronica Taylor, Ph.D.

Key Objectives of NIGMS National Centers for Cryoelectron Microscopy

Screening

• Access to sample preparation equipment
• Access to screening equipment
• Expert assistance

Data Collection​​

• Access to state-of-the-art equipment for collecting high-resolution data
• Expert assistance

Training

• Training programs to help users become independent cryoEM practitioners

• Bacterial riboswitch model, unpublished work from E. Campos Chavez, V. Tokars, and A. Mondragon, image provided by S2C2/Wah Chiu.
• Grid freezing, image provided by Steve Reichow/PNCC
• Training group, image provided by Steve Reichow/PNCC

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