DeWitt Stetten Jr. Lectures

To mark its 20th anniversary, in 1982 NIGMS established an annual lecture to honor DeWitt Stetten Jr., M.D., Ph.D. Dr. Stetten served as NIGMS' third director and had a strong commitment to basic science, especially research in genetics, cellular and molecular biology, and chemistry.

2024 Molecular Mechanisms U​nderlying Glycinergic Neurotransmission​ Sudha Chakrapani, Ph.D.
2023 The Great Escape: Phage Lysis and Its Control​​​ Ry​ Young, Ph.D.
2022 Biomedical Research in Rural America: Much Accomplished, Much To Do​​​ Sally L. Hodder, M.D.
2021 Evolutionary Dynamics of SARS-CoV-2​​ Trevor Bedford, Ph.D.
2020 Rethinking General AnesthesiaEmery N. Brown, M.D., Ph.D.​
2019 Scalable Platforms for Generating RNA Sensors and Controllers Christina Dawn Smolke, Ph.D.
2018 Understanding the Source of Regenerative Ability in AnimalsAlejandro Sánchez Alvarado, Ph.D.
2017 Computing Cures: Discovery Through the Lens of a Computational MicroscopeRommie E. Amaro, Ph.D.
2016 Elements of Health and Disease: Inorganic Fluxes and Metal Receptors That Control Cell Fate DecisionsThomas V. O’Halloran, Ph.D.
2015 Form Meets Function: Structurally Diverse Cilia and Their Roles in Sensory SignalingPiali Sengupta, Ph.D.
2014 The Mechanisms of Cytoskeletal Motor ProteinsRon Vale, Ph.D.
2013 Cancelled
2012 50th Anniversary Symposium
"Population Genetics in the Personal Genome Era: Genomics for the World"
Carlos D. Bustamante, Ph.D.
"Shifting Paradigms for Pharmacologic Research"
Kathy M. Giacomini, Ph.D.
"Microtubules: From Basic Biology to Cancer Drugs and Back Again"
Tim Mitchison, Ph.D.
2011 The Emerging Network of Data for Understanding the Interactions of Genes and DrugsRuss B. Altman, M.D.-Ph.D.
2010 Measuring and Modeling Life-Death Decisions in Single CellsPeter Sorger, Ph.D.
2009 Intra- and Inter-Species Cell-to-Cell Communication in BacteriaBonnie L. Bassler, Ph.D.
2008 The Molecular Basis of Eukaryotic TranscriptionRoger D. Kornberg, Ph.D.
2007 Physiology and Immunology of the Cholinergic Anti-inflammatory PathwayKevin J. Tracey, M.D.
2006 Regulatory Circuitry of Embryonic Stem CellsRichard A. Young, Ph.D.
2005 Chemistry in Living Systems: New Tools for Probing the GlycomeCarolyn R. Bertozzi, Ph.D.
2004 Ion Channels: Life's Electronic HardwareRoderick MacKinnon, M.D.
2003 RNA-Triggered Genetic Silencing MechanismsAndrew Z. Fire, Ph.D.
2002 40th Anniversary Symposium: "Computational Cell Biology"
"EGF Receptor Circuit Operation:A Paradigm from Quantitative Cell Biology"
Douglas A. Lauffenburger, Ph.D.
"The Robustness of Evolved Genetic Networks Would Be Astonishing Were It Not Essential"
Garrett M. Odell, Ph.D.
"The Cell Cycle: Spatial and Temporal Control of a Multicomponent Genetic Network"
Lucy Shapiro, Ph.D.
2001 "Translating the Histone Code: A Tale of Tails"C. David Allis, Ph.D.
2000 "Revealing the Ribosome"
"Decoding the Genetic Information on Ribosomes in Molecular Detail"
Ada E. Yonath, Ph.D.
"Insights from the Structure of the 30S RibosomalSubunit"
Venki Ramakrishnan, Ph.D.
"The Complete Atomic Structure of the Large Ribosomal Subunit from Haloarcula marismortui"
Peter B. Moore, Ph.D.
1999 "Single-Molecule Biomechanics and the Myosin Family of Molecular Motors" James A. Spudich, Ph.D.
1998 "Mad Cows Meet Psi-Chotic Yeast: The Expansion of the Prion Hypothesis" Susan L. Lindquist, Ph.D.
1997 "DNA-Mediated Electron Transfer: Chemistry at a Distance" Jacqueline K. Barton, Ph.D.
1996 "Using Deadly Cone Snails to Learn Drug Design and Probe Nervous Systems" Baldomero M. Olivera, Ph.D.
1995 "Design of Proteins and Drugs" Peter S. Kim, Ph.D.
1994 "A Chemical Approach to Understanding and Controlling Signal Transduction"Stuart L. Schreiber, Ph.D.
1993 "The Spliceosome: A Dynamic Ribonucleoprotein Machine"Christine Guthrie, Ph.D.
1992 30th Anniversary Symposium: "From Basic Research to Biotechnology"
"RNA as an Enzyme: From Chemistry to Biotechnology"
Thomas R. Cech, Ph.D.
"Catalytic Antibodies"
Peter G. Schultz, Ph.D.
"Cellular Biotechnology: Engineering Metabolism for Enhanced Productivity and New Products"
James E. Bailey, Ph.D.
1991 "The Biochemical Machinery Regulating the Cell Division Cycle"Marc W. Kirschner, Ph.D.
1990 "Synthesis of Telomeres"Elizabeth H. Blackburn, Ph.D.
1989 "The Control of Timing and Spatial Organization During Cellular Differentiation"Lucy Shapiro, Ph.D.
1988 "Sequence-Specific Recognition of DNA: A Synthetic Approach"Peter B. Dervan, Ph.D.
1987 25th Anniversary Symposium: "DNA-Protein Interactions in the Control of Gene Expression"
"The trp Repressor: The Chemical Details of a Genetic Switch"
Paul B. Sigler, Ph.D.
"How Proteins See DNA and Turn Genes On and Off"
Mark S. Ptashne, Ph.D.
"What DNA Viruses Are Telling Us About Genetic Regulation in Animal Cells"
Steven L. McKnight, Ph.D.
1986 "Heat Shock: Cellular Response to Environmental Stresses"Mary Lou Pardue, Ph.D.
1985 "The Molecular Basis of Differential Gene Activity"Donald D. Brown, M.D.
1984 "Cellular Signaling: What Does the Structure of the Acetylcholine Receptor Tell Us About Its Function"Robert M. Stroud, Ph.D.
1983 "Left-Handed Z-DNA and the Regulation of Transcription"Alexander Rich, M.D.

"A Molecular Analysis of Genes That Determine Developmental Pathways"

David S. Hogness, Ph.D.