NIGMS supports investigator-initiated clinical research. Focus areas include (with links to Staff Contacts):
Anesthesiology - Research related to anesthesiology and peri-operative pain
Clinical Pharmacology - Research related to drug delivery, biotransformation and disposition, pharmacokinetics, and modeling (however, studies aimed at specific diseases should be discussed with the institutes focused on those missions)
Sepsis - Research related to the etiology of sepsis and septic shock, with emphasis on the host response
Injury and Critical Illness - Research related to injury, including biochemical and physiological changes induced by trauma
Multi-organ and Systemic Disorders - Research related to cellular and molecular mediators of inflammation and innate immunity underlying complex systemic disorders
Wound Healing - Research related to post-injury healing and tissue repair
Investigators are strongly encouraged to consult with NIGMS staff at the earliest stages to plan research grant applications that might involve
Clinical Studies and Trials.
NIGMS supports clinical research training for institutions and individuals. Programs include:
NIGMS supports research and development conducted by U.S. small businesses for activities that have strong potential for commercialization. Programs include:
NIGMS also participates in the Commercialization Readiness Pilot (CRP) program designed to facilitate the transition of previously funded SBIR and STTR Phase 2 and Phase 2B projects to the commercialization stage by providing additional support for technical assistance.
Note a particular interest described in
NOT-GM-20-028, Notice of Special Interest: NIGMS Priorities for Small Business Development of Sepsis Diagnostics and Therapeutics
NIGMS Collaborative Program Grant for Multidisciplinary Teams (RM1) can support an application from a highly integrated team of investigators addressing a single-focus, ambitious, and challenging project that cannot be achieved with individual research grant awards.
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