BioMath Program

NIGMS and the Division of Mathematical Sciences (DMS) at the National Science Foundation (NSF) jointly support this program to address the pressing need to:

  • bring mathematics and statistics into the core of biological and biomedical research.
  • broaden the use of innovative mathematics in understanding life processes.

Applications are accepted once a year and reviewed by a joint NSF/NIGMS panel. For details see NSF Program Solicitation 22-600 and NIH Guide Notice NOT-GM-22-039. Please note that applications should be submitted to the NSF.


  • Supports fundamental research in mathematics and statistics to address questions in biomedical sciences
  • Enhances collaboration between the mathematical science and the biomedical research communities

Application Requirements

Mathematical Innovation

Advances mathematical or statistical theory or methodology

Biological Relevance

Addresses significant biomedical research questions that are within NIGMS mission

Arrow from Mathematical Inoovation to Integration of Mathematics and Biology
Arrow from Biological Relevance to Integration of Mathematics and Biology

Integration of Mathematics and Biology

Well-defined plan for mathematics/statistics to drive discovery and improve understanding of biology

Funded Research

Find details about the program and recent NIGMS awards:

Program Contact

If you are planning to submit a proposal, we encourage you to contact the Management Team via email ( to discuss the suitability of your proposed project for the BioMath program. Email inquiries should include (i) the key personnel (PI, co-PI, and Senior Personnel) and their research expertise, and (ii) brief description (one-page limit) of the biological/biomedical application and the novelty of the proposed mathematical approach.

For additional information, please contact the following NIGMS program director:

Han Nguyen, Ph.D.
Division of Biophysics, Biomedical Technology, and Computational Biosciences
National Institute of General Medical Sciences
National Institutes of Health
45 Center Drive MSC 6200
Bethesda, MD 20892-6200