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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
SARS-CoV-2 nucleocapsid dimer
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In SARS-CoV-2, the virus that causes COVID-19, nucleocapsid is a complex molecule with many functional parts. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media
Fruit fly embryo
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Cells in an early-stage fruit fly embryo, showing the DIAP1 protein (pink), an inhibitor of apoptosis. Hermann Steller, Rockefeller University View Media
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 7
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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media
A dynamic model of the DNA helicase protein complex
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This short video shows a model of the DNA helicase in yeast. This DNA helicase has 11 proteins that work together to unwind DNA during the process of copying it, called DNA replication. Huilin Li, Stony Brook University View Media
Disrupted vascular development in frog embryos
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Disassembly of vasculature in kdr:GFP frogs following addition of 250 µM TBZ. Related to images 3404 and 3505. Hye Ji Cha, University of Texas at Austin View Media
Bacterial glucose isomerase
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A crystal of bacterial glucose isomerase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Space-filling model of a cefotaxime-CCD-1 complex
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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media
Ion channel
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A special "messy" region of a potassium ion channel is important in its function. Yu Zhoi, Christopher Lingle Laboratory, Washington University School of Medicine in St. Louis View Media
Disease-susceptible Arabidopsis leaf
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This is a magnified view of an Arabidopsis thaliana leaf after several days of infection with the pathogen Hyaloperonospora arabidopsidis. Jeff Dangl, University of North Carolina, Chapel Hill View Media
The 26S proteasome engages with a protein substrate
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The proteasome is a critical multiprotein complex in the cell that breaks down and recycles proteins that have become damaged or are no longer needed. Andreas Martin, HHMI View Media
Life of an AIDS virus (with labels)
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HIV is a retrovirus, a type of virus that carries its genetic material not as DNA but as RNA. Crabtree + Company View Media
Dimeric ferredoxin-like protein from an unidentified marine microbe
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This is the first structure of a protein derived from the metagenomic sequences collected during the Sorcerer II Global Ocean Sampling project. Joint Center for Structural Genomics View Media
Zika virus
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Zika virus is shown in cross section at center left. On the outside, it includes envelope protein (red) and membrane protein (magenta) embedded in a lipid membrane (light purple). Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media
Bacterial alpha amylase
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A crystal of bacterial alpha amylase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Hsp33 figure 1
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Featured in the March 15, 2012 issue of Biomedical Beat. Related to Hsp33 Figure 2, image 3355. Ursula Jakob and Dana Reichmann, University of Michigan View Media
Himastatin
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A model of the molecule himastatin, which was first isolated from the bacterium Streptomyces himastatinicus. Himastatin shows antibiotic activity. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media
Nuclear Lamina – Three Views
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Three views of the entire nuclear lamina of a HeLa cell produced by tilted light sheet 3D single-molecule super-resolution imaging using a platform termed TILT3D. Anna-Karin Gustavsson, Ph.D. View Media
Fungal lipase (2)
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Crystals of fungal lipase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Rhodopsin bound to visual arrestin
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Rhodopsin is a pigment in the rod cells of the retina (back of the eye). It is extremely light-sensitive, supporting vision in low-light conditions. Protein Data Bank. View Media
Kinases
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Kinases are enzymes that add phosphate groups (red-yellow structures) to proteins (green), assigning the proteins a code. Crabtree + Company View Media
Bacteriophage P22 capsid
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Cryo-electron microscopy (cryo-EM) has the power to capture details of proteins and other small biological structures at the molecular level. This image shows proteins in the capsid, or outer co Dr. Wah Chiu, Baylor College of Medicine View Media
Jack bean concanavalin A
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Crystals of jack bean concanavalin A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Seeing signaling protein activation in cells 03
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Cdc42, a member of the Rho family of small guanosine triphosphatase (GTPase) proteins, regulates multiple cell functions, including motility, proliferation, apoptosis, and cell morphology. Klaus Hahn, University of North Carolina, Chapel Hill Medical School View Media
Snowflake DNA origami
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An atomic force microscopy image shows DNA folded into an intricate, computer-designed structure. The image is featured on Biomedical Beat blog post Cool Images: A Holiday-Themed Collection. Hao Yan, Arizona State University View Media
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 5
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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media
Cryo-electron microscopy of the dengue virus showing protective membrane and membrane proteins
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Dengue virus is a mosquito-borne illness that infects millions of people in the tropics and subtropics each year. Like many viruses, dengue is enclosed by a protective membrane. Hong Zhou, UCLA View Media
Antitoxin GhoS (Illustration 1)
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Structure of the bacterial antitoxin protein GhoS. GhoS inhibits the production of a bacterial toxin, GhoT, which can contribute to antibiotic resistance. Rebecca Page and Wolfgang Peti, Brown University and Thomas K. Wood, Pennsylvania State University View Media
Bovine trypsin
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A crystal of bovine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Shiga toxin being sorted inside a cell
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Shiga toxin (green) is sorted from the endosome into membrane tubules (red), which then pinch off and move to the Golgi apparatus. Somshuvra Mukhopadhyay, The University of Texas at Austin, and Adam D. Linstedt, Carnegie Mellon University View Media
Zebrafish embryo
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A zebrafish embryo showing its natural colors. Zebrafish have see-through eggs and embryos, making them ideal research organisms for studying the earliest stages of development. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media
Cytochrome structure with anticancer drug
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This image shows the structure of the CYP17A1 enzyme (ribbons colored from blue N-terminus to red C-terminus), with the associated heme colored black. Emily Scott, University of Kansas View Media
CRISPR surveillance complex
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This image shows how the CRISPR surveillance complex is disabled by two copies of anti-CRISPR protein AcrF1 (red) and one AcrF2 (light green). NRAMM National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View Media
VDAC video 01
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This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media
Nicotinic acid phosphoribosyltransferase
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Model of the enzyme nicotinic acid phosphoribosyltransferase. Berkeley Structural Genomics Center, PSI View Media
Trajectories of labeled cell receptors
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Trajectories of single molecule labeled cell surface receptors. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View Media
VDAC video 02
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This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media
CCP enzyme
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The enzyme CCP is found in the mitochondria of baker’s yeast. Scientists study the chemical reactions that CCP triggers, which involve a water molecule, iron, and oxygen. Protein Data Bank. View Media
Serum albumin structure 1
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Serum albumin (SA) is the most abundant protein in the blood plasma of mammals. SA has a characteristic heart-shape structure and is a highly versatile protein. Wladek Minor, University of Virginia View Media
VDAC video 03
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This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media
Cryo-electron microscopy revealing the "wasabi receptor"
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The TRPA1 protein is responsible for the burn you feel when you taste a bite of sushi topped with wasabi. Jean-Paul Armache, UCSF View Media
VDAC-1 (3)
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The structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media
Self-organizing proteins
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Under the microscope, an E. coli cell lights up like a fireball. Each bright dot marks a surface protein that tells the bacteria to move toward or away from nearby food and toxins. View Media
Histones in chromatin (with labels)
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Histone proteins loop together with double-stranded DNA to form a structure that resembles beads on a string. Crabtree + Company View Media
Kappa opioid receptor
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The receptor is shown bound to an antagonist, JDTic. Raymond Stevens, The Scripps Research Institute View Media
Fungal lipase (1)
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Crystals of fungal lipase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Zinc finger
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The structure of a gene-regulating zinc finger protein bound to DNA. Jeremy M. Berg, National Institute of General Medical Sciences View Media
Stetten Lecture 2017poster image
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This image is featured on the poster for Dr. Rommie Amaro's 2017 Stetten Lecture. Dr. Rommie Amaro, University of California, San Diego View Media
Worm sperm
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To develop a system for studying cell motility in unnatrual conditions -- a microscope slide instead of the body -- Tom Roberts and Katsuya Shimabukuro at Florida State University disassembled and rec Tom Roberts, Florida State University View Media
Tiny strands of tubulin, a protein in a cell's skeleton
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Just as our bodies rely on bones for structural support, our cells rely on a cellular skeleton. Pakorn Kanchanawong, National University of Singapore and National Heart, Lung, and Blood Institute, National Institutes of Health; and Clare Waterman, National Heart, Lung, and Blood Institute, National Institutes of Health View Media
Bacteriophage P22 capsid, detail
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Detail of a subunit of the capsid, or outer cover, of bacteriophage P22, a virus that infects the Salmonella bacteria. Dr. Wah Chiu, Baylor College of Medicine View Media
