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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Drugs enter skin

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Drugs enter different layers of skin via intramuscular, subcutaneous, or transdermal delivery methods. See image 2532 for a labeled version of this illustration. Crabtree + Company View Media

ATP synthase

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The world's smallest motor, ATP synthase, generates energy for the cell. See image 2518 for a labeled version of this illustration. Crabtree + Company View Media

White Poppy (cropped)

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A cropped image of a white poppy. View poppy uncropped here 3424. Judy Coyle, Donald Danforth Plant Science Center View Media

Himastatin and bacteria

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A model of the molecule himastatin overlaid on an image of Bacillus subtilis bacteria. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media

Anti-tumor drug ecteinascidin 743 (ET-743) with hydrogens 03

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

Plasma membrane (with labels)

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The plasma membrane is a cell's protective barrier. See image 2523 for an unlabeled version of this illustration. Featured in The Chemistry of Health. Crabtree + Company View Media

Bioluminescent imaging in adult zebrafish 04

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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. View Media

Active Site of E. coli response regulator PhoB

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Active site of E. coli response regulator PhoB. Ann Stock, Rutgers University View Media

Genetically identical mycobacteria respond differently to antibiotic 1

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Antibiotic resistance in microbes is a serious health concern. So researchers have turned their attention to how bacteria undo the action of some antibiotics. Bree Aldridge, Tufts University View Media

X-ray diffraction pattern from a crystallized cefotaxime-CCD-1 complex

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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media

Anti-tumor drug ecteinascidin 743 (ET-743) with hydrogens 01

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

Prion protein fibrils 1

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Recombinant proteins such as the prion protein shown here are often used to model how proteins misfold and sometimes polymerize in neurodegenerative disorders. This prion protein was expressed in E. Ken Pekoc (public affairs officer) and Julie Marquardt, NIAID/ Rocky Mountain Laboratories View Media

Space-filling model of a cefotaxime-CCD-1 complex

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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media

A drug's life in the body

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A drug's life in the body. Medicines taken by mouth pass through the liver before they are absorbed into the bloodstream. Crabtree + Company View Media

Yeast cells responding to a glucose shortage

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These yeast cells were exposed to a glucose (sugar) shortage. Mike Henne, University of Texas Southwestern Medical Center. View Media

Activation energy (with labels)

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To become products, reactants must overcome an energy hill. See image 2525 for an unlabeled version of this illustration. Crabtree + Company View Media

Himastatin

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A model of the molecule himastatin, which was first isolated from the bacterium Streptomyces himastatinicus. Himastatin shows antibiotic activity. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media

Independence Day

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This graphic that resembles a firework was created from a picture of a fruit fly spermatid. Sigi Benjamin-Hong, Rockefeller University View Media

Molecular view of glutamatergic synapse

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This illustration highlights spherical pre-synaptic vesicles that carry the neurotransmitter glutamate. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Glycan arrays

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The signal is obtained by allowing proteins in human serum to interact with glycan (polysaccharide) arrays. The arrays are shown in replicate so the pattern is clear. Ola Blixt, Scripps Research Institute View Media

Glucose and sucrose

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Glucose (top) and sucrose (bottom) are sugars made of carbon, hydrogen, and oxygen atoms. Carbohydrates include simple sugars like these and are the main source of energy for the human body. Crabtree + Company View Media

Aspirin

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Acetylsalicylate (bottom) is the aspirin of today. Crabtree + Company View Media

Quorum-sensing inhibitor limits bacterial growth

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To simulate the consequences of disrupting bacterial cell-to-cell communication, called quorum sensing, in the crypts (small chambers within the colon), the researchers experimented with an inhibitor Minyoung Kevin Kim and Bonnie Bassler, Princeton University View Media

White Poppy

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A white poppy. View cropped image of a poppy here 3423. Judy Coyle, Donald Danforth Plant Science Center View Media

Diversity oriented synthesis: generating skeletal diversity using folding processes

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This 1 1/2-minute video animation was produced for chemical biologist Stuart Schreiber's lab page. The animation shows how diverse chemical structures can be produced in the lab. Eric Keller View Media

Anti-tumor drug ecteinascidin 743 (ET-743) with hydrogens 04

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

In vitro assembly of a cell-signaling pathway

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T cells are white blood cells that are important in defending the body against bacteria, viruses and other pathogens. Xiaolei Su, HHMI Whitman Center of the Marine Biological Laboratory View Media

Kinesin moves cellular cargo

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A protein called kinesin (blue) is in charge of moving cargo around inside cells and helping them divide. Charles Sindelar, Yale University View Media

Antibiotic-surviving bacteria

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Colonies of bacteria growing despite high concentrations of antibiotics. These colonies are visible both by eye, as seen on the left, and by bioluminescence imaging, as seen on the right. Paul Stoodley, The Ohio State University. View Media

Kinases

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Kinases are enzymes that add phosphate groups (red-yellow structures) to proteins (green), assigning the proteins a code. Crabtree + Company View Media

Dynein moving along microtubules

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Dynein (green) is a motor protein that “walks” along microtubules (red, part of the cytoskeleton) and carries its cargo along with it. This video was captured through fluorescence microscopy. Morgan DeSantis, University of Michigan. View Media

Average teen circadian cycle

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Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. Typical circadian rhythms lead to high energy during the middle of the day (10 a.m. NIGMS View Media

Bioluminescence in a Tube

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Details about the basic biology and chemistry of the ingredients that produce bioluminescence are allowing scientists to harness it as an imaging tool. Credit: Nathan Shaner, Scintillon Institute. Nathan Shaner, Scintillon Institute View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 7

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Brain waves of a patient anesthetized with propofol

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A representation of a patient’s brain waves after receiving the anesthetic propofol. Emery N. Brown, M.D., Ph.D., Massachusetts General Hospital/Harvard Medical School, Picower Institute for Learning and Memory, and Massachusetts Institute of Technology. View Media

Crystals of CCD-1 in complex with cefotaxime

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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media

Fruit fly brain responds to adipokines

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Drosophila adult brain showing that an adipokine (fat hormone) generates a response from neurons (aqua) and regulates insulin-producing neurons (red).
Akhila Rajan, Fred Hutchinson Cancer Center View Media

Cascade reaction promoted by water

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This illustration of an epoxide-opening cascade promoted by water emulates the proposed biosynthesis of some of the Red Tide toxins. Tim Jamison, Massachusetts Institute of Technology View Media

Cas4 nuclease protein structure

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This wreath represents the molecular structure of a protein, Cas4, which is part of a system, known as CRISPR, that bacteria use to protect themselves against viral invaders. Fred Dyda, NIDDK View Media

Master clock of the mouse brain

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An image of the area of the mouse brain that serves as the 'master clock,' which houses the brain's time-keeping neurons. The nuclei of the clock cells are shown in blue. Erik Herzog, Washington University in St. Louis View Media

Anti-tumor drug ecteinascidin 743 (ET-743), structure without hydrogens 04

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

Cytochrome structure with anticancer drug

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This image shows the structure of the CYP17A1 enzyme (ribbons colored from blue N-terminus to red C-terminus), with the associated heme colored black. Emily Scott, University of Kansas View Media

Bacillus anthracis being killed

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Bacillus anthracis (anthrax) cells being killed by a fluorescent trans-translation inhibitor, which disrupts bacterial protein synthesis. Kenneth Keiler, Penn State University View Media

Bacillus anthracis being killed

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Bacillus anthracis (anthrax) cells being killed by a fluorescent trans-translation inhibitor, which disrupts bacterial protein synthesis. John Alumasa, Keiler Laboratory, Pennsylvania State University View Media

Bottles of warfarin

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In 2007, the FDA modified warfarin's label to indicate that genetic makeup may affect patient response to the drug. The widely used blood thinner is sold under the brand name Coumadin®. Alisa Machalek, NIGMS/NIH View Media

Circadian rhythms and the SCN

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Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. NIGMS View Media

Chang Shan

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For thousands of years, Chinese herbalists have treated malaria using Chang Shan, a root extract from a type of hydrangea that grows in Tibet and Nepal. Paul Schimmel Lab, Scripps Research Institute View Media

Dose response curves

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Dose-response curves determine how much of a drug (X-axis) causes a particular effect, or a side effect, in the body (Y-axis). Featured in Medicines By Design. Crabtree + Company View Media

Network Map

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This network map shows the overlap (green) between the long QT syndrome (yellow) and epilepsy (blue) protein-interaction neighborhoods located within the human interactome. Seth Berger, Mount Sinai School of Medicine View Media

Ciclo circadiano de un adolescente típico

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Los ritmos circadianos son cambios físicos, mentales y conductuales que siguen un ciclo de 24 horas. NIGMS View Media