National Institute of
Switch to Gallery View
Image and Video Gallery
This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Yeast cells entering mitosis
6791
Yeast cells entering mitosis, also known as cell division. The green and magenta dots are two proteins that play important roles in mitosis. They show where the cells will split. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media
Space-filling model of a cefotaxime-CCD-1 complex
6767
CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media
Pores on the surface of the Hawaiian bobtail squid light organ
7016
The light organ (~0.5 mm across) of a juvenile Hawaiian bobtail squid, Euprymna scolopes, stained blue. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media
Video of Calling Cards in a mouse brain
6781
The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. NIH Director's Blog View Media
Advanced Photon Source (APS) at Argonne National Lab
2358
The intense X-rays produced by synchrotrons such as the Advanced Photon Source are ideally suited for protein structure determination. Southeast Collaboratory for Structural Genomics View Media
Cell-like compartments from frog eggs
6584
Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media
Bacillus anthracis being killed
3525
Bacillus anthracis (anthrax) cells being killed by a fluorescent trans-translation inhibitor, which disrupts bacterial protein synthesis. Kenneth Keiler, Penn State University View Media
An adult Hawaiian bobtail squid
7013
An adult female Hawaiian bobtail squid, Euprymna scolopes, with its mantle cavity exposed from the underside. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media
Snowflake DNA origami
3724
An atomic force microscopy image shows DNA folded into an intricate, computer-designed structure. The image is featured on Biomedical Beat blog post Cool Images: A Holiday-Themed Collection. Hao Yan, Arizona State University View Media
Research mentor and student
2767
A research mentor (Lori Eidson) and student (Nina Waldron, on the microscope) were 2009 members of the BRAIN (Behavioral Research Advancements In Neuroscience) program at Georgia State University in A Elizabeth Weaver, Georgia State University View Media
Structure of amyloid-forming prion protein
3542
This structure from an amyloid-forming prion protein shows one way beta sheets can stack. Douglas Fowler, University of Washington View Media
Bacteriophage P22 capsid, detail
5875
Detail of a subunit of the capsid, or outer cover, of bacteriophage P22, a virus that infects the Salmonella bacteria. Dr. Wah Chiu, Baylor College of Medicine View Media
Nano-rainbow
2326
These vials may look like they're filled with colored water, but they really contain nanocrystals reflecting different colors under ultraviolet light. Shuming Nie, Emory University View Media
Human blood cells with Borrelia hermsii, a bacterium that causes relapsing fever
3586
Relapsing fever is caused by a bacterium and transmitted by certain soft-bodied ticks or body lice. The disease is seldom fatal in humans, but it can be very serious and prolonged. NIAID View Media
3D image of actin in a cell
3749
Actin is an essential protein in a cell's skeleton (cytoskeleton). It forms a dense network of thin filaments in the cell. Xiaowei Zhuang, Howard Hughes Medical Institute, Harvard University View Media
Snowflake yeast 3
6971
Multicellular yeast called snowflake yeast that researchers created through many generations of directed evolution from unicellular yeast. William Ratcliff, Georgia Institute of Technology. View Media
Cryo-ET cross-section of the Golgi apparatus
6606
On the left, a cross-section slice of a rat pancreas cell captured using cryo-electron tomography (cryo-ET). On the right, a 3D, color-coded version of the image highlighting cell structures. Xianjun Zhang, University of Southern California. View Media
Cone snail shell
2576
A shell from the venomous cone snail Conus omaria, which lives in the Pacific and Indian oceans and eats other snails. Kerry Matz, University of Utah View Media
Fruit fly spermatids
3590
Developing spermatids (precursors of mature sperm cells) begin as small, round cells and mature into long-tailed, tadpole-shaped ones. Lacramioara Fabian, The Hospital for Sick Children, Toronto, Canada View Media
Cryo-EM reveals how the HIV capsid attaches to a human protein to evade immune detection
3755
The illustration shows the capsid of human immunodeficiency virus (HIV) whose molecular features were resolved with cryo-electron microscopy (cryo-EM). Juan R. Perilla, University of Illinois at Urbana-Champaign View Media
Nuclear Lamina
6572
The 3D single-molecule super-resolution reconstruction of the entire nuclear lamina in a HeLa cell was acquired using the TILT3D platform. Anna-Karin Gustavsson, Ph.D. View Media
Intasome
6346
Salk researchers captured the structure of a protein complex called an intasome (center) that lets viruses similar to HIV establish permanent infection in their hosts. National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View Media
A molecular switch strips transcription factor from DNA
3729
In this video, Rice University scientists used molecular modeling with a mathematical algorithm called AWSEM (for associative memory, water-mediated, structure and energy model) and structural data to Davit Potoyan and Peter Wolynes View Media
Young squids
6903
Real-time movie of young squids. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media
Network diagram of genes, cellular components and processes (unlabeled)
3436
This image shows the hierarchical ontology of genes, cellular components and processes derived from large genomic datasets. From Dutkowski et al. Janusz Dutkowski and Trey Ideker View Media
Zebrafish embryo
6897
A zebrafish embryo showing its natural colors. Zebrafish have see-through eggs and embryos, making them ideal research organisms for studying the earliest stages of development. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media
DNA replication origin recognition complex (ORC)
3597
A study published in March 2012 used cryo-electron microscopy to determine the structure of the DNA replication origin recognition complex (ORC), a semi-circular, protein complex (yellow) that recogni Huilin Li, Brookhaven National Laboratory View Media
Computer sketch of bird-and-flower DNA origami
3689
A computer-generated sketch of a DNA origami folded into a flower-and-bird structure. See also related image 3690. Hao Yan, Arizona State University View Media
Human endoplasmic reticulum membrane protein complex
6777
A 3D model of the human endoplasmic reticulum membrane protein complex (EMC) that identifies its nine essential subunits. Rebecca Voorhees, California Institute of Technology. View Media
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 2
3414
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media
Yeast cells with Fimbrin Fim1
6794
Yeast cells with the protein Fimbrin Fim1 shown in magenta. This protein plays a role in cell division. This image was captured using wide-field microscopy with deconvolution.Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media
Bence Jones protein MLE
2399
A crystal of Bence Jones protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 1
3413
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media
CRISPR
6351
RNA incorporated into the CRISPR surveillance complex is positioned to scan across foreign DNA. Cryo-EM density from a 3Å reconstruction is shown as a yellow mesh. NRAMM National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View Media
Biosensors illustration
2802
A rendering of an activity biosensor image overlaid with a cell-centered frame of reference used for image analysis of signal transduction. Gaudenz Danuser, Harvard Medical School View Media
CRISPR Illustration Frame 3
6487
This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media
Fruit fly ovaries
6807
Fruit fly (Drosophila melanogaster) ovaries with DNA shown in magenta and actin filaments shown in light blue. This image was captured using a confocal laser scanning microscope.Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View Media
Scientists display X-ray diffraction pattern obtained with split X-ray beamline
2384
Scientists from Argonne National Laboratory's Advanced Photon Source (APS) display the first X-ray diffraction pattern obtained from a protein crystal using a split X-ray beam, the first of its kind a GM/CA Collaborative Access Team View Media
CRISPR Illustration Frame 2
6486
This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media
Adult and juvenile Hawaiian bobtail squids
7010
An adult Hawaiian bobtail squid, Euprymna scolopes, (~4 cm) surrounded by newly hatched juveniles (~2 mm) in a bowl of seawater.Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media
Thermotoga maritima and its metabolic network
2702
A combination of protein structures determined experimentally and computationally shows us the complete metabolic network of a heat-loving bacterium. View Media
Zebrafish head vasculature video
6933
Various views of a zebrafish head with blood vessels shown in purple. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View Media
Lysosomes and microtubules
6889
Lysosomes (yellow) and detyrosinated microtubules (light blue). Lysosomes are bubblelike organelles that take in molecules and use enzymes to break them down. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media
Folding@Home
1276
Stanford University scientist Vijay Pande decided to couple the power of computers with the help of the public. Judith Stoffer View Media
Automated Worm Sorter - 4
3475
Georgia Tech associate professor Hang Lu holds a microfluidic chip that is part of a system that uses artificial intelligence and cutting-edge image processing to automatically examine large number of Georgia Tech/Gary Meek View Media
Cell-like compartments from frog eggs 4
6591
Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media
Pig alpha amylase
2412
Crystals of porcine alpha amylase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Chromium X-ray source
2361
In the determination of protein structures by X-ray crystallography, this unique soft (l = 2.29Å) X-ray source is used to collect anomalous scattering data from protein crystals containing light atoms The Southeast Collaboratory for Structural Genomics View Media
Bioluminescent imaging in adult zebrafish - lateral view
3558
Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View Media
