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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Finding one bug
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A nanometer-sized biosensor can detect a single deadly bacterium in tainted ground beef. How? Weihong Tan, University of Florida in Gainesville View MediaChromatin in human fibroblast
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The nucleus of a human fibroblast cell with chromatin—a substance made up of DNA and proteins—shown in various colors. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View MediaYeast cells with nuclei and contractile rings
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Yeast cells with nuclei shown in green and contractile rings shown in magenta. Nuclei store DNA, and contractile rings help cells divide. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View MediaNano-rainbow
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These vials may look like they're filled with colored water, but they really contain nanocrystals reflecting different colors under ultraviolet light. Shuming Nie, Emory University View MediaYeast cells with Fimbrin Fim1
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Yeast cells with the protein Fimbrin Fim1 shown in magenta. This protein plays a role in cell division. This image was captured using wide-field microscopy with deconvolution.Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media
Activated mast cell surface
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A scanning electron microscope image of an activated mast cell. This image illustrates the interesting topography of the cell membrane, which is populated with receptors. Bridget Wilson, University of New Mexico View MediaMapping brain differences
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This image of the human brain uses colors and shapes to show neurological differences between two people. Arthur Toga, University of California, Los Angeles View MediaBovine trypsin
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A crystal of bovine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaBovine milk alpha-lactalbumin (1)
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A crystal of bovine milk alpha-lactalbumin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaStatistical cartography
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Like a world of its own, this sphere represents all the known chemical reactions in the E. coli bacterium. Luis A. Nunes Amaral, Northwestern University View MediaStaphylococcus aureus aggregates on microstructured titanium surface
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Groups of Staphylococcus aureus bacteria (blue) attached to a microstructured titanium surface (green) that mimics an orthopedic implant used in joint replacement. Paul Stoodley, The Ohio State University. View MediaDengue virus membrane protein structure
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Dengue virus is a mosquito-borne illness that infects millions of people in the tropics and subtropics each year. Like many viruses, dengue is enclosed by a protective membrane. Hong Zhou, UCLA View MediaMagnetic Janus particle activating a T cell
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A Janus particle being used to activate a T cell, a type of immune cell. Yan Yu, Indiana University, Bloomington. View MediaProtein crystals
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Structural biologists create crystals of proteins, shown here, as a first step in a process called X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaTiny points of light in a quantum dot
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This fingertip-shaped group of lights is a microscopic crystal called a quantum dot. About 10,000 times thinner than a sheet of paper, the dot radiates brilliant colors under ultraviolet light. Sandra Rosenthal and James McBride, Vanderbilt University, and Stephen Pennycook, Oak Ridge National Laboratory View MediaHigh-throughput protein structure determination pipeline
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This slide shows the technologies that the Joint Center for Structural Genomics developed for going from gene to structure and how the technologies have been integrated into a high-throughput pipeline Joint Center for Structural Genomics View MediaSingle-cell “radios” video
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Individual cells are color-coded based on their identity and signaling activity using a protein circuit technology developed by the Coyle Lab. Scott Coyle, University of Wisconsin-Madison. View MediaBacterial glucose isomerase
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A crystal of bacterial glucose isomerase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaInsulin production and fat sensing in fruit flies
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Fourteen neurons (magenta) in the adult Drosophila brain produce insulin, and fat tissue sends packets of lipids to the brain via the lipoprotein carriers (green). Akhila Rajan, Fred Hutchinson Cancer Center View MediaColor coding of the Drosophila brain - image
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This image results from a research project to visualize which regions of the adult fruit fly (Drosophila) brain derive from each neural stem cell. Yong Wan from Charles Hansen’s lab, University of Utah. Data preparation and visualization by Masayoshi Ito in the lab of Kei Ito, University of Tokyo. View MediaFruit fly larvae brains showing tubulin
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Two fruit fly (Drosophila melanogaster) larvae brains with neurons expressing fluorescently tagged tubulin protein. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View MediaDeveloping zebrafish fin
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Originally from the waters of India, Nepal, and neighboring countries, zebrafish can now be found swimming in science labs (and home aquariums) throughout the world. Jessica Plavicki View MediaZinc levels in a plant leaf
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Zinc is required for the function of more than 300 enzymes, including those that help regulate gene expression, in various organisms including humans. Suzana Car, Dartmouth College View MediaA molecular interaction network in yeast 1
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The image visualizes a part of the yeast molecular interaction network. Keiichiro Ono, UCSD View MediaElectrostatic map of the adeno-associated virus
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The new highly efficient parallelized DelPhi software was used to calculate the potential map distribution of an entire virus, the adeno-associated virus, which is made up of more than 484,000 atoms. Emil Alexov, Clemson University View MediaDividing cell
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As this cell was undergoing cell division, it was imaged with two microscopy techniques: differential interference contrast (DIC) and confocal. The DIC view appears in blue and shows the entire cell. Dylan T. Burnette, Vanderbilt University School of Medicine. View MediaAutomated crystal screening system
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Automated crystal screening systems such as the one shown here are becoming a common feature at synchrotron and other facilities where high-throughput crystal structure determination is being carried Southeast Collaboratory for Structural Genomics View MediaGlycan arrays
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The signal is obtained by allowing proteins in human serum to interact with glycan (polysaccharide) arrays. The arrays are shown in replicate so the pattern is clear. Ola Blixt, Scripps Research Institute View MediaX-ray crystallography
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X-ray crystallography allows researchers to see structures too small to be seen by even the most powerful microscopes. Crabtree + Company View MediaChromatin in human fibroblast
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The nucleus of a human fibroblast cell with chromatin—a substance made up of DNA and proteins—shown in various colors. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View MediaC. elegans trapped by carnivorous fungus
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Real-time footage of Caenorhabditis elegans, a tiny roundworm, trapped by a carnivorous fungus, Arthrobotrys dactyloides. Michael Shribak, Marine Biological Laboratory/University of Chicago. View MediaMouse colon with gut bacteria
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A section of mouse colon with gut bacteria (center, in green) residing within a protective pocket. Sarkis K. Mazmanian, California Institute of Technology View MediaSmall blood vessels in a mouse retina
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Blood vessels at the back of the eye (retina) are used to diagnose glaucoma and diabetic eye disease. They also display characteristic changes in people with high blood pressure. National Center for Microscopy and Imaging Research View MediaCRISPR Illustration
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaCell-like compartments emerging from scrambled frog eggs 2
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Cell-like compartments spontaneously emerge from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View MediaNuclear Lamina – Three Views
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Three views of the entire nuclear lamina of a HeLa cell produced by tilted light sheet 3D single-molecule super-resolution imaging using a platform termed TILT3D. Anna-Karin Gustavsson, Ph.D. View MediaCells frozen in time
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The fledgling field of X-ray microscopy lets researchers look inside whole cells rapidly frozen to capture their actions at that very moment. Here, a yeast cell buds before dividing into two. Carolyn Larabell, University of California, San Francisco, and the Lawrence Berkeley National Laboratory View MediaAtomic-level structure of the HIV capsid
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This animation shows atoms of the HIV capsid, the shell that encloses the virus's genetic material. Juan R. Perilla and the Theoretical and Computational Biophysics Group, University of Illinois at Urbana-Champaign View MediaA dynamic model of the DNA helicase protein complex
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This short video shows a model of the DNA helicase in yeast. This DNA helicase has 11 proteins that work together to unwind DNA during the process of copying it, called DNA replication. Huilin Li, Stony Brook University View MediaHoneybees marked with paint
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Researchers doing behavioral experiments with honeybees sometimes use paint or enamel to give individual bees distinguishing marks. Gene Robinson, University of Illinois at Urbana-Champaign. View MediaMouse liver labeled with fluorescent probe
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A mouse liver glows after being tagged with specially designed infrared-fluorescent protein (IFP). Xiaokun Shu, University of California, San Diego View MediaThe nascent juvenile light organ of the Hawaiian bobtail squid
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A light organ (~0.5 mm across) of a Hawaiian bobtail squid, Euprymna scolopes, with different tissues are stained various colors. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View MediaFungal lipase (2)
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Crystals of fungal lipase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaCells lining the trachea
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In this image, viewed with a ZEISS ORION NanoFab microscope, the community of cells lining a mouse airway is magnified more than 10,000 times. Eva Mutunga and Kate Klein, University of the District of Columbia and National Institute of Standards and Technology View MediaCryo-EM reveals how the HIV capsid attaches to a human protein to evade immune detection
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The illustration shows the capsid of human immunodeficiency virus (HIV) whose molecular features were resolved with cryo-electron microscopy (cryo-EM). Juan R. Perilla, University of Illinois at Urbana-Champaign View MediaMulticolor STORM
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In 2006, scientists developed an optical microscopy technique enabling them to clearly see individual molecules within cells. In 2007, they took the technique, abbreviated STORM, a step further. Xiaowei Zhuang, Harvard University View MediaMicrotubule breakdown
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Like a building supported by a steel frame, a cell contains its own sturdy internal scaffolding made up of proteins, including microtubules. Eva Nogales, University of California, Berkeley View MediaSingle-Molecule Imaging
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This is a super-resolution light microscope image taken by Hiro Hakozaki and Masa Hoshijima of NCMIR. Tom Deerinck, NCMIR View MediaElectrostatic map of human spermine synthase
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From PDB entry 3c6k, Crystal structure of human spermine synthase in complex with spermidine and 5-methylthioadenosine. Emil Alexov, Clemson University View MediaAutomated Worm Sorter - 4
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Georgia Tech associate professor Hang Lu holds a microfluidic chip that is part of a system that uses artificial intelligence and cutting-edge image processing to automatically examine large number of Georgia Tech/Gary Meek View Media