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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Bond types (with labels)

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Ionic and covalent bonds hold molecules, like sodium chloride and chlorine gas, together. Hydrogen bonds among molecules, notably involving water, also play an important role in biology. Crabtree + Company View Media

Ciclo circadiano de un adolescente típico

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Los ritmos circadianos son cambios físicos, mentales y conductuales que siguen un ciclo de 24 horas. NIGMS View Media

Himastatin, 360-degree view

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A 360-degree view of the molecule himastatin, which was first isolated from the bacterium Streptomyces himastatinicus. Himastatin shows antibiotic activity. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media

Nucleolus subcompartments spontaneously self-assemble 2

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The nucleolus is a small but very important protein complex located in the cell's nucleus. Nilesh Vaidya, Princeton University View Media

Glycan arrays

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The signal is obtained by allowing proteins in human serum to interact with glycan (polysaccharide) arrays. The arrays are shown in replicate so the pattern is clear. Ola Blixt, Scripps Research Institute View Media

See how immune cell acid destroys bacterial proteins

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This animation shows the effect of exposure to hypochlorous acid, which is found in certain types of immune cells, on bacterial proteins. American Chemistry Council View Media

A drug's life in the body

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A drug's life in the body. Medicines taken by mouth pass through the liver before they are absorbed into the bloodstream. Crabtree + Company View Media

Cytochrome structure with anticancer drug

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This image shows the structure of the CYP17A1 enzyme (ribbons colored from blue N-terminus to red C-terminus), with the associated heme colored black. Emily Scott, University of Kansas View Media

ATP synthase (with labels)

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The world's smallest motor, ATP synthase, generates energy for the cell. See image 2517 for an unlabeled version of this illustration. Crabtree + Company View Media

Shiga toxin being sorted inside a cell

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Shiga toxin (green) is sorted from the endosome into membrane tubules (red), which then pinch off and move to the Golgi apparatus. Somshuvra Mukhopadhyay, The University of Texas at Austin, and Adam D. Linstedt, Carnegie Mellon University View Media

Bacillus anthracis being killed

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Bacillus anthracis (anthrax) cells being killed by a fluorescent trans-translation inhibitor, which disrupts bacterial protein synthesis. Kenneth Keiler, Penn State University View Media

Insulin production and fat sensing in fruit flies

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Fourteen neurons (magenta) in the adult Drosophila brain produce insulin, and fat tissue sends packets of lipids to the brain via the lipoprotein carriers (green). Akhila Rajan, Fred Hutchinson Cancer Center View Media

Carbon building blocks (with examples)

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The arrangement of identical molecular components can make a dramatic difference. For example, carbon atoms can be arranged into dull graphite (left) or sparkly diamonds (right). Crabtree + Company View Media

Glucose and sucrose

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Glucose (top) and sucrose (bottom) are sugars made of carbon, hydrogen, and oxygen atoms. Carbohydrates include simple sugars like these and are the main source of energy for the human body. Crabtree + Company View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 6

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Anti-tumor drug ecteinascidin 743 (ET-743) with hydrogens 04

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

Dose response curves

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Dose-response curves determine how much of a drug (X-axis) causes a particular effect, or a side effect, in the body (Y-axis). Featured in Medicines By Design. Crabtree + Company View Media

HIV Capsid

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This image is a computer-generated model of the approximately 4.2 million atoms of the HIV capsid, the shell that contains the virus' genetic material. Juan R. Perilla and the Theoretical and Computational Biophysics Group, University of Illinois at Urbana-Champaign View Media

Active Site of E. coli response regulator PhoB

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Active site of E. coli response regulator PhoB. Ann Stock, Rutgers University View Media

Yeast cells responding to a glucose shortage

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These yeast cells were exposed to a glucose (sugar) shortage. Mike Henne, University of Texas Southwestern Medical Center. View Media

Antibodies in silica honeycomb

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Antibodies are among the most promising therapies for certain forms of cancer, but patients must take them intravenously, exposing healthy tissues to the drug and increasing the risk of side effects. Chenghong Lei, Pacific Northwest National Laboratory & Karl Erik Hellstrom, University of Washington View Media

Human opioid receptor structure superimposed on poppy

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Opioid receptors on the surfaces of brain cells are involved in pleasure, pain, addiction, depression, psychosis, and other conditions. Raymond Stevens, The Scripps Research Institute View Media

O2 reacting with a flavin-dependent enzyme

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Department of Biological Chemistry, University of Michigan View Media

Anti-tumor drug ecteinascidin 743 (ET-743) with hydrogens 03

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

Cancer Cells Glowing from Luciferin

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The activator cancer cell culture, right, contains a chemical that causes the cells to emit light when in the presence of immune cells. Mark Sellmyer, Stanford University School of Medicine View Media

Aspirin

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Acetylsalicylate (bottom) is the aspirin of today. Crabtree + Company View Media

Protein formation

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Proteins are 3D structures made up of smaller units. DNA is transcribed to RNA, which in turn is translated into amino acids. NIGMS, with the folded protein illustration adapted from Jane Richardson, Duke University Medical Center View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 3

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Movie of in vitro assembly of a cell-signaling pathway

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T cells are white blood cells that are important in defending the body against bacteria, viruses and other pathogens. Xiaolei Su, HHMI Whitman Center of the Marine Biological Laboratory View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 1

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Kinases

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Kinases are enzymes that add phosphate groups (red-yellow structures) to proteins (green), assigning the proteins a code. Crabtree + Company View Media

Molecular view of glutamatergic synapse

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This illustration highlights spherical pre-synaptic vesicles that carry the neurotransmitter glutamate. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Genetically identical mycobacteria respond differently to antibiotic 1

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Antibiotic resistance in microbes is a serious health concern. So researchers have turned their attention to how bacteria undo the action of some antibiotics. Bree Aldridge, Tufts University View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 7

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Crystals of CCD-1 in complex with cefotaxime

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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media

Cryo-electron microscopy revealing the "wasabi receptor"

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The TRPA1 protein is responsible for the burn you feel when you taste a bite of sushi topped with wasabi. Jean-Paul Armache, UCSF View Media

Antibiotic-surviving bacteria

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Colonies of bacteria growing despite high concentrations of antibiotics. These colonies are visible both by eye, as seen on the left, and by bioluminescence imaging, as seen on the right. Paul Stoodley, The Ohio State University. View Media

Active site of sulfite oxidase

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Sulfite oxidase is an enzyme that is essential for normal neurological development in children. John Enemark, University of Arizona View Media

Master clock of the mouse brain

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An image of the area of the mouse brain that serves as the 'master clock,' which houses the brain's time-keeping neurons. The nuclei of the clock cells are shown in blue. Erik Herzog, Washington University in St. Louis View Media

Fruit fly brain responds to adipokines

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Drosophila adult brain showing that an adipokine (fat hormone) generates a response from neurons (aqua) and regulates insulin-producing neurons (red).
Akhila Rajan, Fred Hutchinson Cancer Center View Media

A drug's life in the body (with labels)

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A drug's life in the body. Medicines taken by mouth (oral) pass through the liver before they are absorbed into the bloodstream. Crabtree + Company View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 5

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Bioluminescent imaging in adult zebrafish 04

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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. View Media

Bond types

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Ionic and covalent bonds hold molecules, like sodium chloride and chlorine gas, together. Hydrogen bonds among molecules, notably involving water, also play an important role in biology. Crabtree + Company View Media

Cascade reaction promoted by water

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This illustration of an epoxide-opening cascade promoted by water emulates the proposed biosynthesis of some of the Red Tide toxins. Tim Jamison, Massachusetts Institute of Technology View Media

Enzyme reaction

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Enzymes speed up chemical reactions by reducing the amount of energy needed for the reactions. NIGMS View Media

Himastatin

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A model of the molecule himastatin, which was first isolated from the bacterium Streptomyces himastatinicus. Himastatin shows antibiotic activity. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media

Diversity oriented synthesis: generating skeletal diversity using folding processes

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This 1 1/2-minute video animation was produced for chemical biologist Stuart Schreiber's lab page. The animation shows how diverse chemical structures can be produced in the lab. Eric Keller View Media

Quorum-sensing inhibitor limits bacterial growth

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To simulate the consequences of disrupting bacterial cell-to-cell communication, called quorum sensing, in the crypts (small chambers within the colon), the researchers experimented with an inhibitor Minyoung Kevin Kim and Bonnie Bassler, Princeton University View Media

Anti-tumor drug ecteinascidin 743 (ET-743) with hydrogens 02

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media