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Pulsating response to stress in bacteria - video
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By attaching fluorescent proteins to the genetic circuit responsible for B. subtilis's stress response, researchers can observe the cells' pulses as green flashes. Michael Elowitz, Caltech University View MediaRNA strand
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Ribonucleic acid (RNA) has a sugar-phosphate backbone and the bases adenine (A), cytosine (C), guanine (G), and uracil (U). Crabtree + Company View MediaChromosome inside nucleus (with labels)
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The long, stringy DNA that makes up genes is spooled within chromosomes inside the nucleus of a cell. Crabtree + Company View MediaChromosome inside nucleus
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The long, stringy DNA that makes up genes is spooled within chromosomes inside the nucleus of a cell. Crabtree + Company View MediaPrecise development in the fruit fly embryo
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This 2-hour-old fly embryo already has a blueprint for its formation, and the process for following it is so precise that the difference of just a few key molecules can change the plans. Thomas Gregor, Princeton University View MediaNucleotides make up DNA (with labels)
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DNA consists of two long, twisted chains made up of nucleotides. Each nucleotide contains one base, one phosphate molecule, and the sugar molecule deoxyribose. Crabtree + Company View MediaInduced stem cells from adult skin 01
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These cells are induced stem cells made from human adult skin cells that were genetically reprogrammed to mimic embryonic stem cells. James Thomson, University of Wisconsin-Madison View MediaLily mitosis 10
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaDNA replication illustration (with labels)
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During DNA replication, each strand of the original molecule acts as a template for the synthesis of a new, complementary DNA strand. Crabtree + Company View MediaNucleolus subcompartments spontaneously self-assemble 3
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What looks a little like distant planets with some mysterious surface features are actually assemblies of proteins normally found in the cell's nucleolus, a small but very important protein complex lo Nilesh Vaidya, Princeton University View MediaGroup of Culex quinquefasciatus mosquito larvae
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Mosquito larvae with genes edited by CRISPR. Valentino Gantz, University of California, San Diego. View MediaLily mitosis 09
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaA multicolored fish scale 2
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Each of the tiny colored specs in this image is a cell on the surface of a fish scale. Chen-Hui Chen and Kenneth Poss, Duke University View MediaChromosomes after crossing over
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Duplicated pair of chromosomes have exchanged material. Judith Stoffer View MediaGene silencing
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Pretty in pink, the enzyme histone deacetylase (HDA6) stands out against a background of blue-tinted DNA in the nucleus of an Arabidopsis plant cell. Olga Pontes and Craig Pikaard, Washington University View MediaTwo-headed Xenopus laevis tadpole
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Xenopus laevis, the African clawed frog, has long been used as a research organism for studying embryonic development. Michael Klymkowsky, University of Colorado, Boulder View MediaAutomated Worm Sorter - 4
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Georgia Tech associate professor Hang Lu holds a microfluidic chip that is part of a system that uses artificial intelligence and cutting-edge image processing to automatically examine large number of Georgia Tech/Gary Meek View MediaLife of an AIDS virus (with labels)
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HIV is a retrovirus, a type of virus that carries its genetic material not as DNA but as RNA. Crabtree + Company View MediaGFP sperm
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Fruit fly sperm cells glow bright green when they express the gene for green fluorescent protein (GFP). View MediaDynamic cryo-EM model of the human transcription preinitiation complex
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Gene transcription is a process by which information encoded in DNA is transcribed into RNA. Eva Nogales, Berkeley Lab View MediaLily mitosis 02
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaMapping human genetic variation
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This map paints a colorful portrait of human genetic variation around the world. Noah Rosenberg and Martin Soave, University of Michigan View MediaMeiosis illustration
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Meiosis is the process whereby a cell reduces its chromosomes from diploid to haploid in creating eggs or sperm. Crabtree + Company View MediaCas4 nuclease protein structure
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This wreath represents the molecular structure of a protein, Cas4, which is part of a system, known as CRISPR, that bacteria use to protect themselves against viral invaders. Fred Dyda, NIDDK View MediaEndoplasmic reticulum abnormalities
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Human cells with the gene that codes for the protein FIT2 deleted. Green indicates an endoplasmic reticulum (ER) resident protein. Michel Becuwe, Harvard University. View MediaZinc finger
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The structure of a gene-regulating zinc finger protein bound to DNA. Jeremy M. Berg, National Institute of General Medical Sciences View MediaTelomeres on outer edge of nucleus during cell division
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New research shows telomeres moving to the outer edge of the nucleus after cell division, suggesting these caps that protect chromosomes also may play a role in organizing DNA. Laure Crabbe, Jamie Kasuboski and James Fitzpatrick, Salk Institute for Biological Studies View MediaDeveloping Arabidopsis flower buds
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Flower development is a carefully orchestrated, genetically programmed process that ensures that the male (stamen) and female (pistil) organs form in the right place and at the right time in the flowe Nathanaël Prunet, Caltech View MediaInduced stem cells from adult skin 04
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The human skin cells pictured contain genetic modifications that make them pluripotent, essentially equivalent to embryonic stem cells. James Thomson, University of Wisconsin-Madison View MediaGlowing bacteria make a pretty postcard
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This tropical scene, reminiscent of a postcard from Key West, is actually a petri dish containing an artistic arrangement of genetically engineered bacteria. Nathan C. Shaner, The Scintillon Institute View MediaRSV-Infected Cell
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Viral RNA (red) in an RSV-infected cell. Eric Alonas and Philip Santangelo, Georgia Institute of Technology and Emory University View MediaA multicolored fish scale 1
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Each of the colored specs in this image is a cell on the surface of a fish scale. Chen-Hui Chen and Kenneth Poss, Duke University View MediaLily mitosis 12
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaCircadian rhythms and the SCN
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Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. NIGMS View MediaHost infection stimulates antibiotic resistance
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This illustration shows pathogenic bacteria behave like a Trojan horse: switching from antibiotic susceptibility to resistance during infection. View MediaEarly development in Arabidopsis
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Early on, this Arabidopsis plant embryo picks sides: While one end will form the shoot, the other will take root underground. Zachery R. Smith, Jeff Long lab at the Salk Institute for Biological Studies View MediaGenetic mosaicism in fruit flies
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Fat tissue from the abdomen of a genetically mosaic adult fruit fly. Genetic mosaicism means that the fly has cells with different genotypes even though it formed from a single zygote. Akhila Rajan, Fred Hutchinson Cancer Center View MediaHippocampal neuron in culture
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Hippocampal neuron in culture. Dendrites are green, dendritic spines are red and DNA in cell's nucleus is blue. Shelley Halpain, UC San Diego View MediaGenetic patchworks
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Each point in these colorful patchworks represents the correlation between two sleep-associated genes in fruit flies. Susan Harbison and Trudy Mackay, North Carolina State University View MediaInterphase in Xenopus frog cells
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These images show frog cells in interphase. The cells are Xenopus XL177 cells, which are derived from tadpole epithelial cells. The microtubules are green and the chromosomes are blue. Claire Walczak, who took them while working as a postdoc in the laboratory of Timothy Mitchison. View MediaIntrons
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Genes are often interrupted by stretches of DNA (introns, blue) that do not contain instructions for making a protein. Crabtree + Company View MediaTrp_RS - tryptophanyl tRNA-synthetase family of enzymes
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This image represents the structure of TrpRS, a novel member of the tryptophanyl tRNA-synthetase family of enzymes. View MediaDolly the sheep
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Scientists in Scotland were the first to clone an animal, this sheep named Dolly. She later gave birth to Bonnie, the lamb next to her. View MediaChromosomes before crossing over
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Duplicated pair of chromosomes lined up and ready to cross over. Judith Stoffer View MediaCulex quinquefasciatus mosquito larvae
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Mosquito larvae with genes edited by CRISPR swimming in water. Valentino Gantz, University of California, San Diego. View MediaMitotic cell awaits chromosome alignment
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During mitosis, spindle microtubules (red) attach to chromosome pairs (blue), directing them to the spindle equator. View MediaGenetically identical mycobacteria respond differently to antibiotic 2
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Antibiotic resistance in microbes is a serious health concern. So researchers have turned their attention to how bacteria undo the action of some antibiotics. Bree Aldridge, Tufts University View MediaPlanarian stem cell colony
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Planarians are freshwater flatworms that have powerful abilities to regenerate their bodies, which would seem to make them natural model organisms in which to study stem cells. Peter Reddien, Whitehead Institute View MediaNucleolus subcompartments spontaneously self-assemble 2
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The nucleolus is a small but very important protein complex located in the cell's nucleus. Nilesh Vaidya, Princeton University View MediaNucleolus subcompartments spontaneously self-assemble 4
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What looks a little like distant planets with some mysterious surface features are actually assemblies of proteins normally found in the cell's nucleolus, a small but very important protein complex lo Nilesh Vaidya, Princeton University View Media