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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
NCMIR mouse tail
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Stained cross section of a mouse tail. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaBacillus anthracis being killed
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Bacillus anthracis (anthrax) cells being killed by a fluorescent trans-translation inhibitor, which disrupts bacterial protein synthesis. Kenneth Keiler, Penn State University View MediaPlasma membrane (with labels)
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The plasma membrane is a cell's protective barrier. See image 2523 for an unlabeled version of this illustration. Featured in The Chemistry of Health. Crabtree + Company View MediaBody toxins
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Body organs such as the liver and kidneys process chemicals and toxins. These "target" organs are susceptible to damage caused by these substances. Crabtree + Company View MediaSpreading Cells 01
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Cells move forward with lamellipodia and filopodia supported by networks and bundles of actin filaments. Proper, controlled cell movement is a complex process. Rong Li and Praveen Suraneni, Stowers Institute for Medical Research View MediaTaste buds signal different tastes through ATP release
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Taste buds in a mouse tongue epithelium with types I, II, and III taste cells visualized by cell-type-specific fluorescent antibodies. Aki Taruno, Perelman School of Medicine, University of Pennsylvania View MediaMicrotubules in hippocampal neurons
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Microtubules (magenta) in neurons of the hippocampus, a part of the brain involved in learning and memory. Microtubules are strong, hollow fibers that provide structural support to cells. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View MediaCalcium uptake during ATP production in mitochondria
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Living primary mouse embryonic fibroblasts. Mitochondria (green) stained with the mitochondrial membrane potential indicator, rhodamine 123. Nuclei (blue) are stained with DAPI. Lili Guo, Perelman School of Medicine, University of Pennsylvania View MediaNeuron with labeled synapses
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In this image, recombinant probes known as FingRs (Fibronectin Intrabodies Generated by mRNA display) were expressed in a cortical neuron, where they attached fluorescent proteins to either PSD95 (gre Don Arnold and Richard Roberts, University of Southern California. View MediaWorm sperm
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To develop a system for studying cell motility in unnatrual conditions -- a microscope slide instead of the body -- Tom Roberts and Katsuya Shimabukuro at Florida State University disassembled and rec Tom Roberts, Florida State University View MediaIn vitro assembly of a cell-signaling pathway
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T cells are white blood cells that are important in defending the body against bacteria, viruses and other pathogens. Xiaolei Su, HHMI Whitman Center of the Marine Biological Laboratory View MediaCell-like compartments emerging from scrambled frog eggs 4
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Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View MediaTrypanosoma brucei, the cause of sleeping sickness
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Trypanosoma brucei is a single-cell parasite that causes sleeping sickness in humans. Michael Rout, Rockefeller University View MediaMolecular interactions at the astrocyte nuclear membrane
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These ripples of color represent the outer membrane of the nucleus inside an astrocyte, a star-shaped cell inside the brain. Katerina Akassoglou, Gladstone Institute for Neurological Disease & UCSF View MediaNucleolinus
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The nucleolinus is a cellular compartment that has been a lonely bystander in scientific endeavors. Mary Anne Alliegro, Marine Biological Laboratory View MediaZebrafish embryo
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Just 22 hours after fertilization, this zebrafish embryo is already taking shape. By 36 hours, all of the major organs will have started to form. Philipp Keller, Bill Lemon, Yinan Wan, and Kristin Branson, Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Va. View MediaAtomic-level structure of the HIV capsid
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This animation shows atoms of the HIV capsid, the shell that encloses the virus's genetic material. Juan R. Perilla and the Theoretical and Computational Biophysics Group, University of Illinois at Urbana-Champaign View MediaLily mitosis 12
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaNerve cell
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Nerve cells have long, invisibly thin fibers that carry electrical impulses throughout the body. Some of these fibers extend about 3 feet from the spinal cord to the toes. Judith Stoffer View MediaA bundle of myelinated peripheral nerve cells (axons)
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The extracellular matrix (ECM) is most prevalent in connective tissues but also is present between the stems (axons) of nerve cells. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaStaphylococcus aureus aggregating upon contact with synovial fluid
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Staphylococcus aureus bacteria (green) grouping together upon contact with synovial fluid—a viscous substance found in joints. Paul Stoodley, The Ohio State University. View MediaMicrotubule growth
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Map of microtubule growth rates. Rates are color coded. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View MediaMouse Brain Cross Section
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The brain sections are treated with fluorescent antibodies specific to a particular protein and visualized using serial electron microscopy (SEM). Anton Maximov, The Scripps Research Institute, La Jolla, CA View MediaCRISPR surveillance complex
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This image shows how the CRISPR surveillance complex is disabled by two copies of anti-CRISPR protein AcrF1 (red) and one AcrF2 (light green). NRAMM National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View MediaMultivesicular bodies containing intralumenal vesicles assemble at the vacuole 2
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Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View MediaVesicle traffic
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This illustration shows vesicle traffic inside a cell. Judith Stoffer View MediaPulsating response to stress in bacteria - video
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By attaching fluorescent proteins to the genetic circuit responsible for B. subtilis's stress response, researchers can observe the cells' pulses as green flashes. Michael Elowitz, Caltech University View MediaV. Cholerae Biofilm
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Industrious V. cholerae bacteria (yellow) tend to thrive in denser biofilms (left) while moochers (red) thrive in weaker biofilms (right). View MediaSmooth muscle from human ES cells
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These smooth muscle cells were derived from human embryonic stem cells. The nuclei are stained blue, and the proteins of the cytoskeleton are stained green. Alexey Terskikh lab, Burnham Institute for Medical Research, via CIRM View MediaAnglerfish ovary cross-section
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This image captures the spiral-shaped ovary of an anglerfish in cross-section. Once matured, these eggs will be released in a gelatinous, floating mass. James E. Hayden, The Wistar Institute, Philadelphia, Pa. View MediaDeveloping Arabidopsis flower buds
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Flower development is a carefully orchestrated, genetically programmed process that ensures that the male (stamen) and female (pistil) organs form in the right place and at the right time in the flowe Nathanaël Prunet, Caltech View MediaThe Proteasome: The Cell's Trash Processor in Action
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Our cells are constantly removing and recycling molecular waste. This video shows one way cells process their trash. View MediaTiny strands of tubulin, a protein in a cell's skeleton
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Just as our bodies rely on bones for structural support, our cells rely on a cellular skeleton. Pakorn Kanchanawong, National University of Singapore and National Heart, Lung, and Blood Institute, National Institutes of Health; and Clare Waterman, National Heart, Lung, and Blood Institute, National Institutes of Health View MediaBioluminescent imaging in adult zebrafish - overhead view
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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View MediaBone cancer cell
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This image shows an osteosarcoma cell with DNA in blue, energy factories (mitochondria) in yellow, and actin filaments—part of the cellular skeleton—in purple. Dylan Burnette and Jennifer Lippincott-Schwartz, NICHD View MediaIntasome
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Salk researchers captured the structure of a protein complex called an intasome (center) that lets viruses similar to HIV establish permanent infection in their hosts. National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View MediaBirth of a yeast cell
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Yeast make bread, beer, and wine. And like us, yeast can reproduce sexually. A mother and father cell fuse and create one large cell that contains four offspring. Juergen Berger, Max Planck Institute for Developmental Biology, and Maria Langegger, Friedrich Miescher Laboratory of the Max Planck Society, Germany View MediaHuman endoplasmic reticulum membrane protein complex
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A 3D model of the human endoplasmic reticulum membrane protein complex (EMC) that identifies its nine essential subunits. Rebecca Voorhees, California Institute of Technology. View MediaA mammalian eye has approximately 70 different cell types
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The incredible complexity of a mammalian eye (in this case from a mouse) is captured here. Each color represents a different type of cell. Bryan William Jones and Robert E. Marc, University of Utah View MediaMovie of in vitro assembly of a cell-signaling pathway
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T cells are white blood cells that are important in defending the body against bacteria, viruses and other pathogens. Xiaolei Su, HHMI Whitman Center of the Marine Biological Laboratory View MediaInfluenza virus attaches to host membrane (with labels)
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Influenza A infects a host cell when hemagglutinin grips onto glycans on its surface. Crabtree + Company View MediaFly cells
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If a picture is worth a thousand words, what's a movie worth? Denise Montell, Johns Hopkins University School of Medicine View MediaHuman retinal organoid
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A replica of a human retina grown from stem cells. Kevin Eliceiri, University of Wisconsin-Madison. View MediaTracking embryonic zebrafish cells
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To better understand cell movements in developing embryos, researchers isolated cells from early zebrafish embryos and grew them as clusters. Liliana Solnica-Krezel, Washington University School of Medicine in St. Louis. View MediaFruit fly ovary_2
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A fruit fly ovary, shown here, contains as many as 20 eggs. Fruit flies are not merely tiny insects that buzz around overripe fruit--they are a venerable scientific tool. Denise Montell, University of California, Santa Barbara View MediaCells lining the trachea
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In this image, viewed with a ZEISS ORION NanoFab microscope, the community of cells lining a mouse airway is magnified more than 10,000 times. Eva Mutunga and Kate Klein, University of the District of Columbia and National Institute of Standards and Technology View MediaMitosis and meiosis compared-labeled
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Meiosis is used to make sperm and egg cells. During meiosis, a cell's chromosomes are copied once, but the cell divides twice. Judith Stoffer View MediaCalling Cards in a mouse brain
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The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. Allen Yen, Lab of Joseph Dougherty, Washington University School of Medicine in St. Louis. View MediaSynapses in culture
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Cultured hippocampal neurons grown on a substrate of glial cells (astrocytes). The glial cells form the pink/brown underlayment in this image. The tan threads are the neurons. National Center for Microscopy and Imaging Research View MediaQuorum-sensing inhibitor limits bacterial growth
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To simulate the consequences of disrupting bacterial cell-to-cell communication, called quorum sensing, in the crypts (small chambers within the colon), the researchers experimented with an inhibitor Minyoung Kevin Kim and Bonnie Bassler, Princeton University View Media