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NCMIR Kidney Glomeruli
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Stained glomeruli in the kidney. The kidney is an essential organ responsible for disposing wastes from the body and for maintaining healthy ion levels in the blood. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaDraper, shown in the fatbody of a Drosophila melanogaster larva
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The fly fatbody is a nutrient storage and mobilization organ akin to the mammalian liver. The engulfment receptor Draper (green) is located at the cell surface of fatbody cells. Christina McPhee and Eric Baehrecke, University of Massachusetts Medical School View MediaEarly life of a protein
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This illustration represents the early life of a protein—specifically, apomyoglobin—as it is synthesized by a ribosome and emerges from the ribosomal tunnel, which contains the newly formed protein's Silvia Cavagnero, University of Wisconsin, Madison View MediaLily mitosis 12
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaWound healing in process
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Wound healing requires the action of stem cells. Hermann Steller, Rockefeller University View MediaThermotoga maritima and its metabolic network
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A combination of protein structures determined experimentally and computationally shows us the complete metabolic network of a heat-loving bacterium. View MediaRegenerating lizard tail
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The interior of a regenerating lizard tail 14 days after the original tail was amputated. Thomas Lozito, University of Southern California. View MediaAnimal cell
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A typical animal cell, sliced open to reveal a cross-section of organelles. Judith Stoffer View MediaNCMIR kidney-1
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Stained kidney tissue. The kidney is an essential organ responsible for disposing wastes from the body and for maintaining healthy ion levels in the blood. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaMitosis - anaphase
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A cell in anaphase during mitosis: Chromosomes separate into two genetically identical groups and move to opposite ends of the spindle. Judith Stoffer View MediaCalling Cards in a mouse brain
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The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. Allen Yen, Lab of Joseph Dougherty, Washington University School of Medicine in St. Louis. View MediaChromatin in human fibroblast
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The nucleus of a human fibroblast cell with chromatin—a substance made up of DNA and proteins—shown in various colors. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View MediaBody toxins (with labels)
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Body organs such as the liver and kidneys process chemicals and toxins. These "target" organs are susceptible to damage caused by these substances. Crabtree + Company View MediaMouse cerebellum in pink and blue
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The cerebellum is the brain's locomotion control center. Found at the base of your brain, the cerebellum is a single layer of tissue with deep folds like an accordion. National Center for Microscopy and Imaging Research (NCMIR) View MediaNeutrophil-like cells migrating in a microfluidic chip
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Neutrophil-like cells (blue) in a microfluidic chip preferentially migrating toward LTB4 over fMLP. Caroline Jones, University of Texas at Dallas. View MediaCells lining the trachea
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In this image, viewed with a ZEISS ORION NanoFab microscope, the community of cells lining a mouse airway is magnified more than 10,000 times. Eva Mutunga and Kate Klein, University of the District of Columbia and National Institute of Standards and Technology View MediaBrain cells in the hippocampus
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Hippocampal cells in culture with a neuron in green, showing hundreds of the small protrusions known as dendritic spines. Shelley Halpain, UC San Diego View MediaTelomeres on outer edge of nucleus during cell division
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New research shows telomeres moving to the outer edge of the nucleus after cell division, suggesting these caps that protect chromosomes also may play a role in organizing DNA. Laure Crabbe, Jamie Kasuboski and James Fitzpatrick, Salk Institute for Biological Studies View MediaNCMIR Tongue 2
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Microscopy image of a tongue. One in a series of two, see image 5810 National Center for Microscopy and Imaging Research (NCMIR) View MediaCell-like compartments from frog eggs 5
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Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View MediaGenetic imprinting in Arabidopsis
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This delicate, birdlike projection is an immature seed of the Arabidopsis plant. The part in blue shows the cell that gives rise to the endosperm, the tissue that nourishes the embryo. Robert Fischer, University of California, Berkeley View MediaCells use bubble-like structures called vesicles to transport cargo
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Cells use bubble-like structures called vesicles (yellow) to import, transport, and export cargo and in cellular communication. A single cell may be filled with thousands of moving vesicles.Tatyana Svitkina, University of Pennsylvania View Media
Telomerase illustration
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Reactivating telomerase in our cells does not appear to be a good way to extend the human lifespan. Cancer cells reactivate telomerase. Judith Stoffer View MediaCultured cells
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This image of laboratory-grown cells was taken with the help of a scanning electron microscope, which yields detailed images of cell surfaces. Tina Weatherby Carvalho, University of Hawaii at Manoa View MediaDeveloping zebrafish fin
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Originally from the waters of India, Nepal, and neighboring countries, zebrafish can now be found swimming in science labs (and home aquariums) throughout the world. Jessica Plavicki View MediaAssembly of the HIV capsid
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The HIV capsid is a pear-shaped structure that is made of proteins the virus needs to mature and become infective. John Grime and Gregory Voth, The University of Chicago View MediaHuman endoplasmic reticulum membrane protein complex
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A 3D model of the human endoplasmic reticulum membrane protein complex (EMC) that identifies its nine essential subunits. Rebecca Voorhees, California Institute of Technology. View MediaCellular aging
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A protein called tubulin (green) accumulates in the center of a nucleus (outlined in pink) from an aging cell. Maximiliano D'Angelo and Martin Hetzer, Salk Institute View MediaWound healing in process
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Wound healing requires the action of stem cells. Hermann Steller, Rockefeller University View MediaHydra 04
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Hydra magnipapillata is an invertebrate animal used as a model organism to study developmental questions, for example the formation of the body axis. Hiroshi Shimizu, National Institute of Genetics in Mishima, Japan View MediaA bundle of myelinated peripheral nerve cells (axons)
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The extracellular matrix (ECM) is most prevalent in connective tissues but also is present between the stems (axons) of nerve cells. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaSmooth muscle from human ES cells
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These smooth muscle cells were derived from human embryonic stem cells. The nuclei are stained blue, and the proteins of the cytoskeleton are stained green. Alexey Terskikh lab, Burnham Institute for Medical Research, via CIRM View MediaFluorescent microscopy of kidney tissue
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Serum albumin (SA) is the most abundant protein in the blood plasma of mammals. SA has a characteristic heart-shape structure and is a highly versatile protein. Tom Deerinck , National Center for Microscopy and Imaging Research View MediaBioluminescent imaging in adult zebrafish - lateral view
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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View MediaDeveloping nerve cells
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These developing mouse nerve cells have a nucleus (yellow) surrounded by a cell body, with long extensions called axons and thin branching structures called dendrites. Torsten Wittmann, University of California, San Francisco View MediaLipid raft
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Researchers have learned much of what they know about membranes by constructing artificial membranes in the laboratory. Judith Stoffer View MediaMicrotubules in African green monkey cells
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Microtubules in African green monkey cells. Microtubules are strong, hollow fibers that provide cells with structural support. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View MediaFluorescent E. coli bacteria
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Bioengineers were able to coax bacteria to blink in unison on microfluidic chips. They called each blinking bacterial colony a biopixel. Thousands of fluorescent E. Jeff Hasty Lab, UC San Diego View MediaTransmission electron microscopy of myelinated axons with ECM between the axons
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The extracellular matrix (ECM) is most prevalent in connective tissues but also is present between the stems (axons) of nerve cells, as shown here. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaHippocampal neuron from rodent brain
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Hippocampal neuron from rodent brain with dendrites shown in blue. The hundreds of tiny magenta, green and white dots are the dendritic spines of excitatory synapses. Shelley Halpain, UC San Diego View MediaInterphase in Xenopus frog cells
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These images show frog cells in interphase. The cells are Xenopus XL177 cells, which are derived from tadpole epithelial cells. The microtubules are green and the chromosomes are blue. Claire Walczak, who took them while working as a postdoc in the laboratory of Timothy Mitchison. View MediaNuclear Lamina
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The 3D single-molecule super-resolution reconstruction of the entire nuclear lamina in a HeLa cell was acquired using the TILT3D platform. Anna-Karin Gustavsson, Ph.D. View MediaBioluminescent imaging in adult zebrafish 04
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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. View MediaRed blood cells
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This image of human red blood cells was obtained with the help of a scanning electron microscope, an instrument that uses a finely focused electron beam to yield detailed images of the surface of a sa Tina Weatherby Carvalho, University of Hawaii at Manoa View MediaCell-like compartments emerging from scrambled frog eggs 3
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Cell-like compartments spontaneously emerge from scrambled frog eggs. Endoplasmic reticulum (red) and microtubules (green) are visible. Video created using epifluorescence microscopy. Xianrui Cheng, Stanford University School of Medicine. View MediaHydra 03
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Hydra magnipapillata is an invertebrate animal used as a model organism to study developmental questions, for example the formation of the body axis. Hiroshi Shimizu, National Institute of Genetics in Mishima, Japan View MediaMultivesicular bodies containing intralumenal vesicles assemble at the vacuole 2
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Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View MediaInduced pluripotent stem cells from skin 02
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These induced pluripotent stem cells (iPS cells) were derived from a woman's skin. Blue show nuclei. Green show a protein found in iPS cells but not in skin cells (NANOG). Kathrin Plath lab, University of California, Los Angeles, via CIRM View MediaBacillus anthracis being killed
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Bacillus anthracis (anthrax) cells being killed by a fluorescent trans-translation inhibitor, which disrupts bacterial protein synthesis. Kenneth Keiler, Penn State University View MediaInduced stem cells from adult skin 02
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These cells are induced stem cells made from human adult skin cells that were genetically reprogrammed to mimic embryonic stem cells. James Thomson, University of Wisconsin-Madison View Media