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CRISPR Illustration Frame 2
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaNucleotides make up DNA (with labels)
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DNA consists of two long, twisted chains made up of nucleotides. Each nucleotide contains one base, one phosphate molecule, and the sugar molecule deoxyribose. Crabtree + Company View MediaLily mitosis 05
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaCulex quinquefasciatus mosquito larvae
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Mosquito larvae with genes edited by CRISPR swimming in water. Valentino Gantz, University of California, San Diego. View MediaDynamic cryo-EM model of the human transcription preinitiation complex
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Gene transcription is a process by which information encoded in DNA is transcribed into RNA. Eva Nogales, Berkeley Lab View MediaInduced stem cells from adult skin 03
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The human skin cells pictured contain genetic modifications that make them pluripotent, essentially equivalent to embryonic stem cells. James Thomson, University of Wisconsin-Madison View MediaXenopus laevis egg
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Xenopus laevis, the African clawed frog, has long been used as a model organism for studying embryonic development. Michael Klymkowsky, University of Colorado, Boulder View MediaCross section of a Drosophila melanogaster pupa
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This photograph shows a magnified view of a Drosophila melanogaster pupa in cross section. Compare this normal pupa to one that lacks an important receptor, shown in image 2759. Christina McPhee and Eric Baehrecke, University of Massachusetts Medical School View MediaEndoplasmic reticulum abnormalities
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Human cells with the gene that codes for the protein FIT2 deleted. Green indicates an endoplasmic reticulum (ER) resident protein. Michel Becuwe, Harvard University. View MediaChromosomes before crossing over
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Duplicated pair of chromosomes lined up and ready to cross over. Judith Stoffer View MediaZebrafish embryo
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Just 22 hours after fertilization, this zebrafish embryo is already taking shape. By 36 hours, all of the major organs will have started to form. Philipp Keller, Bill Lemon, Yinan Wan, and Kristin Branson, Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Va. View MediaMicroscopy image of bird-and-flower DNA origami
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An atomic force microscopy image shows DNA folded into an intricate, computer-designed structure. Hao Yan, Arizona State University View MediaDicty fruit
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Dictyostelium discoideum is a microscopic amoeba. A group of 100,000 form a mound as big as a grain of sand. Featured in The New Genetics. View MediaZebrafish larva
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You are face to face with a 6-day-old zebrafish larva. What look like eyes will become nostrils, and the bulges on either side will become eyes. Oscar Ruiz and George Eisenhoffer, University of Texas MD Anderson Cancer Center, Houston View MediaDisease-resistant Arabidopsis leaf
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This is a magnified view of an Arabidopsis thaliana leaf a few days after being exposed to the pathogen Hyaloperonospora arabidopsidis. Jeff Dangl, University of North Carolina, Chapel Hill View MediaChromosomes after crossing over
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Duplicated pair of chromosomes have exchanged material. Judith Stoffer View MediaNucleolus subcompartments spontaneously self-assemble 3
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What looks a little like distant planets with some mysterious surface features are actually assemblies of proteins normally found in the cell's nucleolus, a small but very important protein complex lo Nilesh Vaidya, Princeton University View MediaCRISPR Illustration Frame 5
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. This is the fifthframe in a series of five. View MediaFluorescence in situ hybridization (FISH) in mouse ES cells shows DNA interactions
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Researchers used fluorescence in situ hybridization (FISH) to confirm the presence of long range DNA-DNA interactions in mouse embryonic stem cells. Kathrin Plath, University of California, Los Angeles View MediaMosaicism in C. elegans (White Background)
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In the worm C. elegans, double-stranded RNA made in neurons can silence matching genes in a variety of cell types through the transport of RNA between cells. Snusha Ravikumar, Ph.D., University of Maryland, College Park, and Antony M. Jose, Ph.D., University of Maryland, College Park View MediaArabidopsis Thaliana: Flowers Spring to Life
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This image capture shows how a single gene, STM, plays a starring role in plant development. Nathanaёl Prunet NIH Support: National Institute of General Medical Sciences View MediaGene silencing
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Pretty in pink, the enzyme histone deacetylase (HDA6) stands out against a background of blue-tinted DNA in the nucleus of an Arabidopsis plant cell. Olga Pontes and Craig Pikaard, Washington University View MediaDeveloping Arabidopsis flower buds
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Flower development is a carefully orchestrated, genetically programmed process that ensures that the male (stamen) and female (pistil) organs form in the right place and at the right time in the flowe Nathanaël Prunet, Caltech View MediaCircadian rhythm (with labels)
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The human body keeps time with a master clock called the suprachiasmatic nucleus or SCN. Crabtree + Company View MediaChromosome inside nucleus (with labels)
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The long, stringy DNA that makes up genes is spooled within chromosomes inside the nucleus of a cell. Crabtree + Company View MediaLily mitosis 11
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A light microscope image of cells from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaCircadian rhythms and the SCN
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Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. NIGMS View MediaGFP sperm
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Fruit fly sperm cells glow bright green when they express the gene for green fluorescent protein (GFP). View MediaRepairing DNA
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Like a watch wrapped around a wrist, a special enzyme encircles the double helix to repair a broken strand of DNA. Tom Ellenberger, Washington University School of Medicine View MediaFused, dicentric chromosomes
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This fused chromosome has two functional centromeres, shown as two sets of red and green dots. Beth A. Sullivan, Duke University View MediaFruit fly ovary_2
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A fruit fly ovary, shown here, contains as many as 20 eggs. Fruit flies are not merely tiny insects that buzz around overripe fruit--they are a venerable scientific tool. Denise Montell, University of California, Santa Barbara View MediaCentromeres on human chromosomes
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Human metaphase chromosomes are visible with fluorescence in vitro hybridization (FISH). Centromeric alpha satellite DNA (green) are found in the heterochromatin at each centromere. Peter Warburton, Mount Sinai School of Medicine View MediaLife of an AIDS virus (with labels and stages)
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HIV is a retrovirus, a type of virus that carries its genetic material not as DNA but as RNA. Crabtree + Company View MediaMitotic cell awaits chromosome alignment
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During mitosis, spindle microtubules (red) attach to chromosome pairs (blue), directing them to the spindle equator. View MediaKatanin protein regulates anaphase
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The microtubule severing protein, katanin, localizes to chromosomes and regulates anaphase A in mitosis. David Sharp, Albert Einstein College of Medicine View MediaGenetically identical mycobacteria respond differently to antibiotic 2
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Antibiotic resistance in microbes is a serious health concern. So researchers have turned their attention to how bacteria undo the action of some antibiotics. Bree Aldridge, Tufts University View MediaDNA and actin in cultured fibroblast cells
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DNA (blue) and actin (red) in cultured fibroblast cells. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaIntroduction to Genome Editing Using CRISPR/Cas9
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Genome editing using CRISPR/Cas9 is a rapidly expanding field of scientific research with emerging applications in disease treatment, medical therapeutics and bioenergy, just to name a few. Janet Iwasa View MediaGenetic patchworks
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Each point in these colorful patchworks represents the correlation between two sleep-associated genes in fruit flies. Susan Harbison and Trudy Mackay, North Carolina State University View MediaFruit fly ovaries
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Fruit fly (Drosophila melanogaster) ovaries with DNA shown in magenta and actin filaments shown in light blue. This image was captured using a confocal laser scanning microscope.Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View Media
Assembly of the HIV capsid
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The HIV capsid is a pear-shaped structure that is made of proteins the virus needs to mature and become infective. John Grime and Gregory Voth, The University of Chicago View MediaHIV enzyme
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These images model the molecular structures of three enzymes with critical roles in the life cycle of the human immunodeficiency virus (HIV). Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaHighlighted cells
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The cytoskeleton (green) and DNA (purple) are highlighed in these cells by immunofluorescence. Torsten Wittmann, Scripps Research Institute View MediaLily mitosis 12
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaEarly development in Arabidopsis
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Early on, this Arabidopsis plant embryo picks sides: While one end will form the shoot, the other will take root underground. Zachery R. Smith, Jeff Long lab at the Salk Institute for Biological Studies View MediaNucleolus subcompartments spontaneously self-assemble 1
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The nucleolus is a small but very important protein complex located in the cell's nucleus. Nilesh Vaidya, Princeton University View MediaEpigenetic code (with labels)
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The "epigenetic code" controls gene activity with chemical tags that mark DNA (purple diamonds) and the "tails" of histone proteins (purple triangles). Crabtree + Company View MediaLos ritmos circadianos y el núcleo supraquiasmático
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Los ritmos circadianos son cambios físicos, mentales y de comportamiento que siguen un ciclo de 24 horas. NIGMS View MediaSymmetrically and asymmetrically elongating cells
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Merged fluorescent images of symmetrically (left) or asymmetrically (right) elongating HeLa cells at the end of early anaphase (magenta) and late anaphase (green). Tomomi Kiyomitsu and Iain M. Cheeseman, Whitehead Institute for Biomedical Research View MediaMosaicism in C. elegans (Black Background)
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In the worm C. elegans, double-stranded RNA made in neurons can silence matching genes in a variety of cell types through the transport of RNA between cells. Snusha Ravikumar, Ph.D., University of Maryland, College Park, and Antony M. Jose, Ph.D., University of Maryland, College Park View Media