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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Pig trypsin crystal

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A crystal of pig trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Centrioles anchor cilia in planaria

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Centrioles (green) anchor cilia (red), which project on the surface of pharynx cells of the freshwater planarian Schmidtea mediterranea. Juliette Azimzadeh, University of California, San Francisco View Media

NMR spectrometer

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This photo shows a Varian Unity Inova 900 MHz, 21.1 T standard bore magnet Nuclear Magnetic Resonnance (NMR) spectrometer. Center for Eukaryotic Structural Genomics View Media

Neural circuits in worms similar to those in humans

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Green and yellow fluorescence mark the processes and cell bodies of some C. elegans neurons. Shawn Xu, University of Michigan View Media

Hydra 03

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Hydra magnipapillata is an invertebrate animal used as a model organism to study developmental questions, for example the formation of the body axis. Hiroshi Shimizu, National Institute of Genetics in Mishima, Japan View Media

Yeast art depicting the New York City skyline

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This skyline of New York City was created by “printing” nanodroplets containing yeast (Saccharomyces cerevisiae) onto a large plate. Each dot is a separate yeast colony. Michael Shen, Ph.D., Jasmine Temple, Leslie Mitchell, Ph.D., and Jef Boeke, Ph.D., New York University School of Medicine; and Nick Phillips, James Chuang, Ph.D., and Jiarui Wang, Johns Hopkins University. View Media

Sea urchin embryo 01

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Stereo triplet of a sea urchin embryo stained to reveal actin filaments (orange) and microtubules (blue). George von Dassow, University of Washington View Media

Quorum-sensing inhibitor limits bacterial growth

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To simulate the consequences of disrupting bacterial cell-to-cell communication, called quorum sensing, in the crypts (small chambers within the colon), the researchers experimented with an inhibitor Minyoung Kevin Kim and Bonnie Bassler, Princeton University View Media

Fibroblasts with nuclei in blue, energy factories in green and the actin cytoskeleton in red

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The cells shown here are fibroblasts, one of the most common cells in mammalian connective tissue. These particular cells were taken from a mouse embryo. Dylan Burnette, NICHD View Media

Zinc finger

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The structure of a gene-regulating zinc finger protein bound to DNA. Jeremy M. Berg, National Institute of General Medical Sciences View Media

Fruit fly nurse cells during egg development

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In many animals, the egg cell develops alongside sister cells. Adam C. Martin, Massachusetts Institute of Technology. View Media

Electrostatic map of the adeno-associated virus with scale

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The new highly efficient parallelized DelPhi software was used to calculate the potential map distribution of an entire virus, the adeno-associated virus, which is made up of more than 484,000 atoms. Emil Alexov, Clemson University View Media

Protein purification facility

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The Center for Eukaryotic Structural Genomics protein purification facility is responsible for purifying all recombinant proteins produced by the center. Center for Eukaryotic Structural Genomics View Media

Protein purification robot in action 01

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A robot is transferring 96 purification columns to a vacuum manifold for subsequent purification procedures. The Northeast Collaboratory for Structural Genomics View Media

Endothelial cell

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This image shows two components of the cytoskeleton, microtubules (green) and actin filaments (red), in an endothelial cell derived from a cow lung. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media

Zebrafish embryo

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A zebrafish embryo showing its natural colors. Zebrafish have see-through eggs and embryos, making them ideal research organisms for studying the earliest stages of development. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media

Lily mitosis 07

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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View Media

A Bacillus subtilis biofilm grown in a Petri dish

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Bacterial biofilms are tightly knit communities of bacterial cells growing on, for example, solid surfaces, such as in water pipes or on teeth. Gürol Süel, UCSD View Media

From DNA to Protein

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Nucleotides in DNA are copied into RNA, where they are read three at a time to encode the amino acids in a protein. Many parts of a protein fold as the amino acids are strung together.
Crabtree + Company View Media

Nuclear Lamina – Three Views

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Three views of the entire nuclear lamina of a HeLa cell produced by tilted light sheet 3D single-molecule super-resolution imaging using a platform termed TILT3D. Anna-Karin Gustavsson, Ph.D. View Media

HeLa cell undergoing division into two daughter cells

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Here, a human HeLa cell (a type of immortal cell line used in laboratory experiments) is undergoing cell division. Dylan T. Burnette, Ph.D., Vanderbilt University School of Medicine. View Media

Cross section of a Drosophila melanogaster pupa lacking Draper

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In the absence of the engulfment receptor Draper, salivary gland cells (light blue) persist in the thorax of a developing Drosophila melanogaster pupa. Christina McPhee and Eric Baehrecke, University of Massachusetts Medical School View Media

Circadian rhythm

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The human body keeps time with a master clock called the suprachiasmatic nucleus or SCN. Crabtree + Company View Media

Mitochondrion from insect flight muscle

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This is a tomographic reconstruction of a mitochondrion from an insect flight muscle. National Center for Microscopy and Imaging Research View Media

Snowflake yeast 1

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Multicellular yeast called snowflake yeast that researchers created through many generations of directed evolution from unicellular yeast. William Ratcliff, Georgia Institute of Technology. View Media

Himastatin and bacteria

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A model of the molecule himastatin overlaid on an image of Bacillus subtilis bacteria. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media

Sortase b from B. anthracis

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Structure of sortase b from the bacterium B. anthracis, which causes anthrax. Sortase b is an enzyme used to rob red blood cells of iron, which the bacteria need to survive. Midwest Center for Structural Genomics, PSI View Media

Serum albumin structure 1

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Serum albumin (SA) is the most abundant protein in the blood plasma of mammals. SA has a characteristic heart-shape structure and is a highly versatile protein. Wladek Minor, University of Virginia View Media

Hydra 06

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Hydra magnipapillata is an invertebrate animal used as a model organism to study developmental questions, for example the formation of the body axis. Hiroshi Shimizu, National Institute of Genetics in Mishima, Japan View Media

Advanced Photon Source (APS) at Argonne National Lab

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The intense X-rays produced by synchrotrons such as the Advanced Photon Source are ideally suited for protein structure determination. Southeast Collaboratory for Structural Genomics View Media

Heat shock protein complex from Methanococcus jannaschii

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Model based on X-ray crystallography of the structure of a small heat shock protein complex from the bacteria, Methanococcus jannaschii. Berkeley Structural Genomics Center, PSI-1 View Media

Disease-resistant Arabidopsis leaf

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This is a magnified view of an Arabidopsis thaliana leaf a few days after being exposed to the pathogen Hyaloperonospora arabidopsidis. Jeff Dangl, University of North Carolina, Chapel Hill View Media

Pathways: What's the Connection? | Different Jobs in a Science Lab

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Learn about some of the different jobs in a scientific laboratory and how researchers work as a team to make discoveries. National Institute of General Medical Sciences View Media

The 26S proteasome engages with a protein substrate

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The proteasome is a critical multiprotein complex in the cell that breaks down and recycles proteins that have become damaged or are no longer needed. Andreas Martin, HHMI View Media

Recombinant DNA (with labels)

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To splice a human gene (in this case, the one for insulin) into a plasmid, scientists take the plasmid out of an E. Crabtree + Company View Media

Trp_RS - tryptophanyl tRNA-synthetase family of enzymes

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This image represents the structure of TrpRS, a novel member of the tryptophanyl tRNA-synthetase family of enzymes. View Media

Natcher Building 04

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NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View Media

Xenopus laevis embryos

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Xenopus laevis, the African clawed frog, has long been used as a model organism for studying embryonic development. The frog embryo on the left lacks the developmental factor Sizzled. Michael Klymkowsky, University of Colorado, Boulder View Media

Protein kinases as cancer chemotherapy targets

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Protein kinases—enzymes that add phosphate groups to molecules—are cancer chemotherapy targets because they play significant roles in almost all aspects of cell function, are tightly regulated, and co Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Petri dish containing C. elegans

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This Petri dish contains microscopic roundworms called Caenorhabditis elegans. Researchers used these particular worms to study how C. H. Robert Horvitz and Dipon Ghosh, Massachusetts Institute of Technology. View Media

Independence Day

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This graphic that resembles a firework was created from a picture of a fruit fly spermatid. Sigi Benjamin-Hong, Rockefeller University View Media

Artificial cilia exhibit spontaneous beating

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Researchers have created artificial cilia that wave like the real thing. Zvonimir Dogic View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 4

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Human ES cells differentiating into neurons

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This image shows hundreds of human embryonic stem cells in various stages of differentiating into neurons. Guoping Fan lab, University of California, Los Angeles, via CIRM View Media

Fly cells live

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If a picture is worth a thousand words, what's a movie worth? Denise Montell, Johns Hopkins University School of Medicine View Media

Chromosome inside nucleus (with labels)

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The long, stringy DNA that makes up genes is spooled within chromosomes inside the nucleus of a cell. Crabtree + Company View Media

Yeast cells with Fimbrin Fim1

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Yeast cells with the protein Fimbrin Fim1 shown in magenta. This protein plays a role in cell division. This image was captured using wide-field microscopy with deconvolution.
Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media

Cells use bubble-like structures called vesicles to transport cargo

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Cells use bubble-like structures called vesicles (yellow) to import, transport, and export cargo and in cellular communication. A single cell may be filled with thousands of moving vesicles.
Tatyana Svitkina, University of Pennsylvania View Media

The nascent juvenile light organ of the Hawaiian bobtail squid

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A light organ (~0.5 mm across) of a Hawaiian bobtail squid, Euprymna scolopes, with different tissues are stained various colors. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media

¿Qué es la sepsis? (Sepsis Infographic)

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La sepsis o septicemia es la respuesta fulminante y extrema del cuerpo a una infección. En los Estados Unidos, más de 1.7 millones de personas contraen sepsis cada año. Instituto Nacional de Ciencias Médicas Generales View Media