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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Mouse retina close-up

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Keunyoung ("Christine") Kim National Center for Microscopy and Imaging Research (NCMIR) View Media

A mammalian eye has approximately 70 different cell types

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The incredible complexity of a mammalian eye (in this case from a mouse) is captured here. Each color represents a different type of cell. Bryan William Jones and Robert E. Marc, University of Utah View Media

Enzyme transition states

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The molecule on the left is an electrostatic potential map of the van der Waals surface of the transition state for human purine nucleoside phosphorylase. Vern Schramm, Albert Einstein College of Medicine of Yeshiva University View Media

Hydra 02

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Hydra magnipapillata is an invertebrate animal used as a model organism to study developmental questions, for example the formation of the body axis. Hiroshi Shimizu, National Institute of Genetics in Mishima, Japan View Media

NCMIR mouse tail

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Stained cross section of a mouse tail. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Chromium X-ray source

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In the determination of protein structures by X-ray crystallography, this unique soft (l = 2.29Å) X-ray source is used to collect anomalous scattering data from protein crystals containing light atoms The Southeast Collaboratory for Structural Genomics View Media

Lily mitosis 01

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A light microscope image shows the chromosomes, stained dark blue, in a dividing cell of an African globe lily (Scadoxus katherinae). Andrew S. Bajer, University of Oregon, Eugene View Media

Himastatin, 360-degree view

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A 360-degree view of the molecule himastatin, which was first isolated from the bacterium Streptomyces himastatinicus. Himastatin shows antibiotic activity. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media

Chemokine CXCR4 receptor

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The receptor is shown bound to a small molecule peptide called CVX15. Raymond Stevens, The Scripps Research Institute View Media

Influenza virus attaches to host membrane

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Influenza A infects a host cell when hemagglutinin grips onto glycans on its surface. Crabtree + Company View Media

Microtubules in African green monkey cells

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Microtubules in African green monkey cells. Microtubules are strong, hollow fibers that provide cells with structural support. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media

Electrostatic map of the adeno-associated virus

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The new highly efficient parallelized DelPhi software was used to calculate the potential map distribution of an entire virus, the adeno-associated virus, which is made up of more than 484,000 atoms. Emil Alexov, Clemson University View Media

Natcher Building 05

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NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View Media

Biopixels

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Bioengineers were able to coax bacteria to blink in unison on microfluidic chips. This image shows a small chip with about 500 blinking bacterial colonies or biopixels. Jeff Hasty Lab, UC San Diego View Media

Cell in two stages of division

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This image shows a cell in two stages of division: prometaphase (top) and metaphase (bottom). Lilian Kabeche, Dartmouth View Media

Precisely Delivering Chemical Cargo to Cells

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Moving protein or other molecules to specific cells to treat or examine them has been a major biological challenge. Nature Nanotechnology View Media

Cross section of a Drosophila melanogaster pupa

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This photograph shows a magnified view of a Drosophila melanogaster pupa in cross section. Compare this normal pupa to one that lacks an important receptor, shown in image 2759. Christina McPhee and Eric Baehrecke, University of Massachusetts Medical School View Media

Structure of heme, top view

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Molecular model of the struture of heme. Heme is a small, flat molecule with an iron ion (dark red) at its center. Rachel Kramer Green, RCSB Protein Data Bank View Media

Sea urchin embryo 05

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Stereo triplet of a sea urchin embryo stained to reveal actin filaments (orange) and microtubules (blue). George von Dassow, University of Washington View Media

Animal cell membrane

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The membrane that surrounds a cell is made up of proteins and lipids. Judith Stoffer View Media

Anti-tumor drug ecteinascidin 743 (ET-743), structure without hydrogens 04

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

Animal cell

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A typical animal cell, sliced open to reveal a cross-section of organelles. Judith Stoffer View Media

The Proteasome: The Cell's Trash Processor in Action

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Our cells are constantly removing and recycling molecular waste. This video shows one way cells process their trash. View Media

Antitoxin GhoS (Illustration 2)

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Structure of the bacterial antitoxin protein GhoS. GhoS inhibits the production of a bacterial toxin, GhoT, which can contribute to antibiotic resistance. Rebecca Page and Wolfgang Peti, Brown University and Thomas K. Wood, Pennsylvania State University View Media

Breast cancer cells change migration phenotypes

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Cancer cells can change their migration phenotype, which includes their shape and the way that they move to invade different tissues. Bo Sun, Oregon State University. View Media

Protein purification robot

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Irina Dementieva, a biochemist, and Youngchang Kim, a biophysicist and crystallographer, work with the first robot of its type in the U.S. to automate protein purification. Midwest Center for Structural Genomics View Media

Dying melanoma cells

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Melanoma (skin cancer) cells undergoing programmed cell death, also called apoptosis. This process was triggered by raising the pH of the medium that the cells were growing in. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media

See how immune cell acid destroys bacterial proteins

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This animation shows the effect of exposure to hypochlorous acid, which is found in certain types of immune cells, on bacterial proteins. American Chemistry Council View Media

Pollen grains: male germ cells in plants and a cause of seasonal allergies

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Those of us who get sneezy and itchy-eyed every spring or fall may have pollen grains, like those shown here, to blame. Edna, Gil, and Amit Cukierman, Fox Chase Cancer Center, Philadelphia, Pa. View Media

String-like Ebola virus peeling off an infected cell

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After multiplying inside a host cell, the stringlike Ebola virus is emerging to infect more cells. Heinz Feldmann, Peter Jahrling, Elizabeth Fischer and Anita Mora, National Institute of Allergy and Infectious Diseases, National Institutes of Health View Media

Epithelial cell migration

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High-resolution time lapse of epithelial (skin) cell migration and wound healing. It shows an image taken every 13 seconds over the course of almost 14 minutes. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media

Mapping brain differences

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This image of the human brain uses colors and shapes to show neurological differences between two people. Arthur Toga, University of California, Los Angeles View Media

Multivesicular bodies containing intralumenal vesicles assemble at the vacuole 2

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Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View Media

Pulsating response to stress in bacteria - video

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By attaching fluorescent proteins to the genetic circuit responsible for B. subtilis's stress response, researchers can observe the cells' pulses as green flashes. Michael Elowitz, Caltech University View Media

Atomic-level structure of the HIV capsid

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This animation shows atoms of the HIV capsid, the shell that encloses the virus's genetic material. Juan R. Perilla and the Theoretical and Computational Biophysics Group, University of Illinois at Urbana-Champaign View Media

Simulation of controlled avian flu outbreak

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This video shows a controlled outbreak of transmissible avian flu among people living in Thailand. Neil M. Ferguson, Imperial College London View Media

Peripheral nerve cells derived from ES cells

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Peripheral nerve cells made from human embryonic stem cell-derived neural crest stem cells. Stephen Dalton, University of Georgia View Media

TFIID complex binds DNA to start gene transcription

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Gene transcription is a process by which the genetic information encoded in DNA is transcribed into RNA. Eva Nogales, Berkeley Lab View Media

DNA replication origin recognition complex (ORC)

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A study published in March 2012 used cryo-electron microscopy to determine the structure of the DNA replication origin recognition complex (ORC), a semi-circular, protein complex (yellow) that recogni Huilin Li, Brookhaven National Laboratory View Media

Cell toxins

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A number of environmental factors cause DNA mutations that can lead to cancer: toxins in cigarette smoke, sunlight and other radiation, and some viruses. Judith Stoffer View Media

Neural development

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Using techniques that took 4 years to design, a team of developmental biologists showed that certain proteins can direct the subdivision of fruit fly and chicken nervous system tissue into the regions Mieko Mizutani and Ethan Bier, University of California, San Diego, and Henk Roelink, University of Washington View Media

Hen egg lysozyme (1)

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Crystals of hen egg lysozyme protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Los ritmos circadianos y el núcleo supraquiasmático

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Los ritmos circadianos son cambios físicos, mentales y de comportamiento que siguen un ciclo de 24 horas. NIGMS View Media

VDAC video 03

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This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media

Fruit fly larvae brains showing tubulin

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Two fruit fly (Drosophila melanogaster) larvae brains with neurons expressing fluorescently tagged tubulin protein. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View Media

Body toxins

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Body organs such as the liver and kidneys process chemicals and toxins. These "target" organs are susceptible to damage caused by these substances. Crabtree + Company View Media

Enzymes convert subtrates into products

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Enzymes convert substrates into products very quickly. See image 2522 for a labeled version of this illustration. Featured in The Chemistry of Health. Crabtree + Company View Media

Biosensors illustration

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A rendering of an activity biosensor image overlaid with a cell-centered frame of reference used for image analysis of signal transduction. Gaudenz Danuser, Harvard Medical School View Media

Bubonic plague bacteria on part of the digestive system in a rat flea

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Here, bubonic plague bacteria (yellow) are shown in the digestive system of a rat flea (purple). The bubonic plague killed a third of Europeans in the mid-14th century. NIAID View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 2

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media