Image and Video Gallery
This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Ear hair cells derived from embryonic stem cells
3272
Mouse embryonic stem cells matured into this bundle of hair cells similar to the ones that transmit sound in the ear. Stefen Heller, Stanford University, via CIRM View MediaAnti-tumor drug ecteinascidin 743 (ET-743), structure without hydrogens 04
2797
Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View MediaHuman embryonic stem cells on feeder cells
3274
This fluorescent microscope image shows human embryonic stem cells whose nuclei are stained green. Blue staining shows the surrounding supportive feeder cells. Michael Longaker lab, Stanford University School of Medicine, via CIRM View MediaFrom DNA to Protein
2509
Nucleotides in DNA are copied into RNA, where they are read three at a time to encode the amino acids in a protein. Many parts of a protein fold as the amino acids are strung together. Crabtree + Company View MediaSkin cross-section
1056
Cross-section of skin anatomy shows layers and different tissue types. National Institutes of Health Medical Arts View MediaA panorama view of cells
5761
This photograph shows a panoramic view of HeLa cells, a cell line many researchers use to study a large variety of important research questions. Tom Deerinck, National Center for Microscopy and Imaging Research View MediaGlowing bacteria make a pretty postcard
3492
This tropical scene, reminiscent of a postcard from Key West, is actually a petri dish containing an artistic arrangement of genetically engineered bacteria. Nathan C. Shaner, The Scintillon Institute View MediaSmooth ER
1292
The endoplasmic reticulum comes in two types: Rough ER is covered with ribosomes and prepares newly made proteins; smooth ER specializes in making lipids and breaking down toxic molecules. Judith Stoffer View MediaMounting of protein crystals
2368
Automated methods using micromachined silicon are used at the Northeast Collaboratory for Structural Genomics to mount protein crystals for X-ray crystallography. The Northeast Collaboratory for Structural Genomics View MediaAutomated crystal screening system
2362
Automated crystal screening systems such as the one shown here are becoming a common feature at synchrotron and other facilities where high-throughput crystal structure determination is being carried Southeast Collaboratory for Structural Genomics View MediaCell-free protein synthesizers
2360
Both instruments shown were developed by CellFree Sciences of Yokohama, Japan. Center for Eukaryotic Structural Genomics View MediaA multicolored fish scale 1
3782
Each of the colored specs in this image is a cell on the surface of a fish scale. Chen-Hui Chen and Kenneth Poss, Duke University View MediaChromatin in human fibroblast
6888
The nucleus of a human fibroblast cell with chromatin—a substance made up of DNA and proteins—shown in various colors. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View MediaFour timepoints in gastrulation
3334
It has been said that gastrulation is the most important event in a person's life. Bob Goldstein, University of North Carolina, Chapel Hill View MediaElectrostatic map of the adeno-associated virus with scale
3375
The new highly efficient parallelized DelPhi software was used to calculate the potential map distribution of an entire virus, the adeno-associated virus, which is made up of more than 484,000 atoms. Emil Alexov, Clemson University View MediaDynein moving along microtubules
7023
Dynein (green) is a motor protein that “walks” along microtubules (red, part of the cytoskeleton) and carries its cargo along with it. This video was captured through fluorescence microscopy. Morgan DeSantis, University of Michigan. View MediaRelapsing fever bacterium (gray) and red blood cells
3585
Relapsing fever is caused by a bacterium and transmitted by certain soft-bodied ticks or body lice. The disease is seldom fatal in humans, but it can be very serious and prolonged. NIAID View MediaXenopus laevis egg
2753
Xenopus laevis, the African clawed frog, has long been used as a model organism for studying embryonic development. Michael Klymkowsky, University of Colorado, Boulder View MediaScanning electron microscopy of collagen fibers
3735
This image shows collagen, a fibrous protein that's the main component of the extracellular matrix (ECM). Collagen is a strong, ropelike molecule that forms stretch-resistant fibers. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaEndoplasmic reticulum
2649
Fluorescent markers show the interconnected web of tubes and compartments in the endoplasmic reticulum. The protein atlastin helps build and maintain this critical part of cells. Andrea Daga, Eugenio Medea Scientific Institute (Conegliano, Italy) View MediaQuorum-sensing inhibitor limits bacterial growth
3728
To simulate the consequences of disrupting bacterial cell-to-cell communication, called quorum sensing, in the crypts (small chambers within the colon), the researchers experimented with an inhibitor Minyoung Kevin Kim and Bonnie Bassler, Princeton University View MediaCryo-EM reveals how the HIV capsid attaches to a human protein to evade immune detection
3755
The illustration shows the capsid of human immunodeficiency virus (HIV) whose molecular features were resolved with cryo-electron microscopy (cryo-EM). Juan R. Perilla, University of Illinois at Urbana-Champaign View MediaChromosomes after crossing over
1314
Duplicated pair of chromosomes have exchanged material. Judith Stoffer View MediaTEM cross-section of C. elegans (roundworm)
5759
The worm Caenorhabditis elegans is a popular laboratory animal because its small size and fairly simple body make it easy to study. Piali Sengupta, Brandeis University View MediaCell toxins
1312
A number of environmental factors cause DNA mutations that can lead to cancer: toxins in cigarette smoke, sunlight and other radiation, and some viruses. Judith Stoffer View MediaCluster analysis of mysterious protein
3295
Researchers use cluster analysis to study protein shape and function. Each green circle represents one potential shape of the protein mitoNEET. Patricia Jennings and Elizabeth Baxter, University of California, San Diego View MediaProtein crystals
1060
Structural biologists create crystals of proteins, shown here, as a first step in a process called X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaH1 histamine receptor
3360
The receptor is shown bound to an inverse agonist, doxepin. Raymond Stevens, The Scripps Research Institute View MediaColor-coded chromosomes
2312
By mixing fluorescent dyes like an artist mixes paints, scientists are able to color code individual chromosomes. Anna Jauch, Institute of Human Genetics, Heidelberg, Germany View MediaBacteriophage P22 capsid, detail
5875
Detail of a subunit of the capsid, or outer cover, of bacteriophage P22, a virus that infects the Salmonella bacteria. Dr. Wah Chiu, Baylor College of Medicine View MediaWhite Poppy
3424
A white poppy. View cropped image of a poppy here 3423. Judy Coyle, Donald Danforth Plant Science Center View MediaMouse colon with gut bacteria
3566
A section of mouse colon with gut bacteria (center, in green) residing within a protective pocket. Sarkis K. Mazmanian, California Institute of Technology View MediaBence Jones protein MLE
2399
A crystal of Bence Jones protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaTrajectories of labeled cell receptors
2801
Trajectories of single molecule labeled cell surface receptors. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View MediaHeLa cell undergoing division into two daughter cells
6520
Here, a human HeLa cell (a type of immortal cell line used in laboratory experiments) is undergoing cell division. Dylan T. Burnette, Ph.D., Vanderbilt University School of Medicine. View MediaTranslation
1281
Ribosomes manufacture proteins based on mRNA instructions. Each ribosome reads mRNA, recruits tRNA molecules to fetch amino acids, and assembles the amino acids in the proper order. Judith Stoffer View MediaCell-like compartments emerging from scrambled frog eggs
6587
Cell-like compartments spontaneously emerge from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View MediaNeuron with labeled synapses
3509
In this image, recombinant probes known as FingRs (Fibronectin Intrabodies Generated by mRNA display) were expressed in a cortical neuron, where they attached fluorescent proteins to either PSD95 (gre Don Arnold and Richard Roberts, University of Southern California. View MediaTransmission electron microscopy of coronary artery wall with elastin-rich ECM pseudocolored in light brown
3738
Elastin is a fibrous protein in the extracellular matrix (ECM). It is abundant in artery walls like the one shown here. As its name indicates, elastin confers elasticity. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaMouse brain slice showing nerve cells
6901
A 20-µm thick section of mouse midbrain. The nerve cells are transparent and weren’t stained. Michael Shribak, Marine Biological Laboratory/University of Chicago. View MediaBioluminescence in a Tube
5895
Details about the basic biology and chemistry of the ingredients that produce bioluminescence are allowing scientists to harness it as an imaging tool. Credit: Nathan Shaner, Scintillon Institute. Nathan Shaner, Scintillon Institute View MediaHeLa cells
3522
Multiphoton fluorescence image of cultured HeLa cells with a fluorescent protein targeted to the Golgi apparatus (orange), microtubules (green) and counterstained for DNA (cyan). National Center for Microscopy and Imaging Research (NCMIR) View MediaAnchor cell in basement membrane
2707
An anchor cell (red) pushes through the basement membrane (green) that surrounds it. Elliott Hagedorn, Duke University. View MediaH1N1 Influenza Virus
6356
Related to image 6355. Dr. Rommie Amaro, University of California, San Diego View MediaFruit fly brain responds to adipokines
6985
Drosophila adult brain showing that an adipokine (fat hormone) generates a response from neurons (aqua) and regulates insulin-producing neurons (red).Akhila Rajan, Fred Hutchinson Cancer Center View Media
Microtubule dynamics in real time
2784
Cytoplasmic linker protein (CLIP)-170 is a microtubule plus-end-tracking protein that regulates microtubule dynamics and links microtubule ends to different intracellular structures. Gary Borisy, Marine Biology Laboratory View MediaMouse heart fibroblasts
3281
This image shows mouse fetal heart fibroblast cells. The muscle protein actin is stained red, and the cell nuclei are stained blue. Kara McCloskey lab, University of California, Merced, via CIRM View MediaFrom DNA to Protein (labeled)
2510
The genetic code in DNA is transcribed into RNA, which is translated into proteins with specific sequences. Crabtree + Company View MediaVideo of Calling Cards in a mouse brain
6781
The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. NIH Director's Blog View Media