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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Fly by night
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This fruit fly expresses green fluorescent protein (GFP) in the same pattern as the period gene, a gene that regulates circadian rhythm and is expressed in all sensory neurons on the surface of the fl Jay Hirsh, University of Virginia View MediaBrain waves of a patient anesthetized with propofol
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A representation of a patient’s brain waves after receiving the anesthetic propofol. Emery N. Brown, M.D., Ph.D., Massachusetts General Hospital/Harvard Medical School, Picower Institute for Learning and Memory, and Massachusetts Institute of Technology. View MediaPig trypsin crystal
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A crystal of pig trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaYeast cells pack a punch
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Although they are tiny, microbes that are growing in confined spaces can generate a lot of pressure. In this video, yeast cells grow in a small chamber called a microfluidic bioreactor. Oskar Hallatschek, UC Berkeley View MediaA molecular interaction network in yeast 2
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The image visualizes a part of the yeast molecular interaction network. Keiichiro Ono, UCSD View MediaFlagellated bacterial cells
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Vibrio fischeri (2 mm in length) is the exclusive symbiotic partner of the Hawaiian bobtail squid, Euprymna scolopes. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View MediaFour timepoints in gastrulation
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It has been said that gastrulation is the most important event in a person's life. Bob Goldstein, University of North Carolina, Chapel Hill View MediaCell division and cell death
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Two cells over a 2-hour period. The one on the bottom left goes through programmed cell death, also known as apoptosis. The one on the top right goes through cell division, also called mitosis. Dylan T. Burnette, Vanderbilt University School of Medicine. View MediaDinosaur evolutionary tree
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Analysis of 68 million-year-old collagen molecule fragments preserved in a T. Chris Organ, Harvard University View MediaCalcium uptake during ATP production in mitochondria
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Living primary mouse embryonic fibroblasts. Mitochondria (green) stained with the mitochondrial membrane potential indicator, rhodamine 123. Nuclei (blue) are stained with DAPI. Lili Guo, Perelman School of Medicine, University of Pennsylvania View MediaKupffer cell residing in the liver
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Kupffer cells appear in the liver during the early stages of mammalian development and stay put throughout life to protect liver cells, clean up old red blood cells, and regulate iron levels. Thomas Deerinck, National Center for Microscopy and Imaging Research, University of California, San Diego. View MediaWound healing in process
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Wound healing requires the action of stem cells. Hermann Steller, Rockefeller University View MediaIntasome
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Salk researchers captured the structure of a protein complex called an intasome (center) that lets viruses similar to HIV establish permanent infection in their hosts. National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View MediaGenetically identical mycobacteria respond differently to antibiotic 1
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Antibiotic resistance in microbes is a serious health concern. So researchers have turned their attention to how bacteria undo the action of some antibiotics. Bree Aldridge, Tufts University View MediaIon channel
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A special "messy" region of a potassium ion channel is important in its function. Yu Zhoi, Christopher Lingle Laboratory, Washington University School of Medicine in St. Louis View MediaMouse mammary cells lacking anti-cancer protein
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Shortly after a pregnant woman gives birth, her breasts start to secrete milk. This process is triggered by hormonal and genetic cues, including the protein Elf5. Nature Cell Biology, November 2012, Volume 14 No 11 pp1113-1231 View MediaNeural development
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Using techniques that took 4 years to design, a team of developmental biologists showed that certain proteins can direct the subdivision of fruit fly and chicken nervous system tissue into the regions Mieko Mizutani and Ethan Bier, University of California, San Diego, and Henk Roelink, University of Washington View MediaDiversity oriented synthesis: generating skeletal diversity using folding processes
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This 1 1/2-minute video animation was produced for chemical biologist Stuart Schreiber's lab page. The animation shows how diverse chemical structures can be produced in the lab. Eric Keller View MediaZebrafish embryo
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A zebrafish embryo showing its natural colors. Zebrafish have see-through eggs and embryos, making them ideal research organisms for studying the earliest stages of development. Michael Shribak, Marine Biological Laboratory/University of Chicago. View MediaBody toxins
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Body organs such as the liver and kidneys process chemicals and toxins. These "target" organs are susceptible to damage caused by these substances. Crabtree + Company View MediaLysosomes and microtubules
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Lysosomes (yellow) and detyrosinated microtubules (light blue). Lysosomes are bubblelike organelles that take in molecules and use enzymes to break them down. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View MediaMouse brain slice showing nerve cells
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A 20-µm thick section of mouse midbrain. The nerve cells are transparent and weren’t stained. Michael Shribak, Marine Biological Laboratory/University of Chicago. View MediaSeeing signaling protein activation in cells 04
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Cdc42, a member of the Rho family of small guanosine triphosphatase (GTPase) proteins, regulates multiple cell functions, including motility, proliferation, apoptosis, and cell morphology. Klaus Hahn, University of North Carolina, Chapel Hill Medical School View MediaARTS triggers apoptosis
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Cell showing overproduction of the ARTS protein (red). ARTS triggers apoptosis, as shown by the activation of caspase-3 (green) a key tool in the cell's destruction. The nucleus is shown in blue. Hermann Steller, Rockefeller University View MediaX-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 2
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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View MediaPlasma-Derived Membrane Vesicles
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This fiery image doesn’t come from inside a bubbling volcano. Instead, it shows animal cells caught in the act of making bubbles, or blebbing. Jeanne Stachowiak, University of Texas at Austin View MediaProtective membrane and membrane proteins of the dengue virus visualized with cryo-EM
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Dengue virus is a mosquito-borne illness that infects millions of people in the tropics and subtropics each year. Like many viruses, dengue is enclosed by a protective membrane. Hong Zhou, UCLA View MediaMycobacterium tuberculosis
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Mycobacterium tuberculosis, the bacterium that causes tuberculosis, has infected one-quarter of the world's population and causes more than one million deaths each year, according to the Reuben Peters, Iowa State University View MediaComputer sketch of bird-and-flower DNA origami
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A computer-generated sketch of a DNA origami folded into a flower-and-bird structure. See also related image 3690. Hao Yan, Arizona State University View MediaBrain showing hallmarks of Alzheimer's disease
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Along with blood vessels (red) and nerve cells (green), this mouse brain shows abnormal protein clumps known as plaques (blue). Alvin Gogineni, Genentech View MediaBacteria in the mouse colon
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Image of the colon of a mouse mono-colonized with Bacteroides fragilis (red) residing within the crypt channel. The red staining is due to an antibody to B. Sarkis K. Mazmanian, California Institute of Technology View MediaHuman fibroblast undergoing cell division
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During cell division, cells physically divide after separating their genetic material to create two daughter cells that are genetically identical to the parent cell. Nilay Taneja, Vanderbilt University, and Dylan T. Burnette, Ph.D., Vanderbilt University School of Medicine. View MediaInterphase in Xenopus frog cells
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These images show frog cells in interphase. The cells are Xenopus XL177 cells, which are derived from tadpole epithelial cells. The microtubules are green and the chromosomes are blue. Claire Walczak, who took them while working as a postdoc in the laboratory of Timothy Mitchison. View MediaZebrafish head vasculature video
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Various views of a zebrafish head with blood vessels shown in purple. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View MediaDDR2 Receptors Attach to Collagen in Breast Tumor
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On the left, the boundary of a breast tumor (yellow) attaches to collagen fibers that are closest to it (green) using DDR2. On the right, a tumor without DDR2 remains disconnected from the collagen. Callie Corsa and Suzanne Ponik, Washington University School of Medicine in St. Louis View MediaPodocytes from a chronically diseased kidney
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This scanning electron microscope (SEM) image shows podocytes--cells in the kidney that play a vital role in filtering waste from the bloodstream--from a patient with chronic kidney disease. Olga Troyanskaya, Princeton University and Matthias Kretzler, University of Michigan View Media3D image of actin in a cell
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Actin is an essential protein in a cell's skeleton (cytoskeleton). It forms a dense network of thin filaments in the cell. Xiaowei Zhuang, Howard Hughes Medical Institute, Harvard University View MediaDrosophila (fruit fly) myosin 1D motility assay
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Actin gliding powered by myosin 1D. Note the counterclockwise motion of the gliding actin filaments. Serapion Pyrpassopoulos and E. Michael Ostap, University of Pennsylvania View MediaHeLa cell undergoing division into two daughter cells
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Here, a human HeLa cell (a type of immortal cell line used in laboratory experiments) is undergoing cell division. Dylan T. Burnette, Ph.D., Vanderbilt University School of Medicine. View MediaCatalase diversity
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Catalases are some of the most efficient enzymes found in cells. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaDeveloping Arabidopsis flower buds
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Flower development is a carefully orchestrated, genetically programmed process that ensures that the male (stamen) and female (pistil) organs form in the right place and at the right time in the flowe Nathanaël Prunet, Caltech View MediaString-like Ebola virus peeling off an infected cell
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After multiplying inside a host cell, the stringlike Ebola virus is emerging to infect more cells. Heinz Feldmann, Peter Jahrling, Elizabeth Fischer and Anita Mora, National Institute of Allergy and Infectious Diseases, National Institutes of Health View MediaFluorescence in situ hybridization (FISH) in mouse ES cells shows DNA interactions
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Researchers used fluorescence in situ hybridization (FISH) to confirm the presence of long range DNA-DNA interactions in mouse embryonic stem cells. Kathrin Plath, University of California, Los Angeles View MediaX-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 7
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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View MediaDrugs enter skin
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Drugs enter different layers of skin via intramuscular, subcutaneous, or transdermal delivery methods. See image 2532 for a labeled version of this illustration. Crabtree + Company View MediaHuman liver cell (hepatocyte)
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Hepatocytes, like the one shown here, are the most abundant type of cell in the human liver. Donna Beer Stolz, University of Pittsburgh View MediaLeptospira bacteria
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Leptospira, shown here in green, is a type (genus) of elongated, spiral-shaped bacteria. Infection can cause Weil's disease, a kind of jaundice, in humans. Tina Weatherby Carvalho, University of Hawaii at Manoa View MediaInfluenza virus attaches to host membrane (with labels)
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Influenza A infects a host cell when hemagglutinin grips onto glycans on its surface. Crabtree + Company View MediaCentral dogma, illustrated
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DNA encodes RNA, which encodes protein. DNA is transcribed to make messenger RNA (mRNA). The mRNA sequence (dark red strand) is complementary to the DNA sequence (blue strand). Crabtree + Company View MediaCryogenic storage tanks at the Coriell Institute for Medical Research
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Established in 1953, the Coriell Institute for Medical Research distributes cell lines and DNA samples to researchers around the world. Courtney Sill, Coriell Institute for Medical Research View Media