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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Telomeres
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The 46 human chromosomes are shown in blue, with the telomeres appearing as white pinpoints. Hesed Padilla-Nash and Thomas Ried, the National Cancer Institute, a part of NIH View Media
Hawaiian bobtail squid
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An adult Hawaiian bobtail squid, Euprymna scolopes, swimming next to a submerged hand. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media
Yeast art depicting the New York City skyline
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This skyline of New York City was created by “printing” nanodroplets containing yeast (Saccharomyces cerevisiae) onto a large plate. Each dot is a separate yeast colony. Michael Shen, Ph.D., Jasmine Temple, Leslie Mitchell, Ph.D., and Jef Boeke, Ph.D., New York University School of Medicine; and Nick Phillips, James Chuang, Ph.D., and Jiarui Wang, Johns Hopkins University. View Media
Central dogma, illustrated
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DNA encodes RNA, which encodes protein. DNA is transcribed to make messenger RNA (mRNA). The mRNA sequence (dark red strand) is complementary to the DNA sequence (blue strand). Crabtree + Company View Media
Quartered torso
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Cells function within organs and tissues, such as the lungs, heart, intestines, and kidney. Judith Stoffer View Media
Dividing cell
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As this cell was undergoing cell division, it was imaged with two microscopy techniques: differential interference contrast (DIC) and confocal. The DIC view appears in blue and shows the entire cell. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media
NCMIR Intestine-1
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The small intestine is where most of our nutrients from the food we eat are absorbed into the bloodstream. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
Wound healing in process
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Wound healing requires the action of stem cells. Hermann Steller, Rockefeller University View Media
A molecular interaction network in yeast 1
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The image visualizes a part of the yeast molecular interaction network. Keiichiro Ono, UCSD View Media
Shiga toxin
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E. coli bacteria normally live harmlessly in our intestines, but some cause disease by making toxins. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media
Natcher Building 01
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NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View Media
Fruit fly retina 02
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Section of a fruit fly retina showing the light-sensing molecules rhodopsin-5 (blue) and rhodopsin-6 (red). Hermann Steller, Rockefeller University View Media
RNA strand
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Ribonucleic acid (RNA) has a sugar-phosphate backbone and the bases adenine (A), cytosine (C), guanine (G), and uracil (U). Crabtree + Company View Media
VDAC video 02
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This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media
Scanning electron microscopy of collagen fibers
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This image shows collagen, a fibrous protein that's the main component of the extracellular matrix (ECM). Collagen is a strong, ropelike molecule that forms stretch-resistant fibers. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
Flagellated bacterial cells
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Vibrio fischeri (2 mm in length) is the exclusive symbiotic partner of the Hawaiian bobtail squid, Euprymna scolopes. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media
PanC from M. tuberculosis
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Model of an enzyme, PanC, that is involved in the last step of vitamin B5 biosynthesis in Mycobacterium tuberculosis. PanC is essential for the growth of M. Mycobacterium Tuberculosis Center, PSI View Media
Dividing cell in metaphase
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This image of a mammalian epithelial cell, captured in metaphase, was the winning image in the high- and super-resolution microscopy category of the 2012 GE Healthcare Life Sciences Cell Imaging Compe Jane Stout in the laboratory of Claire Walczak, Indiana University, GE Healthcare 2012 Cell Imaging Competition View Media
Himastatin, 360-degree view
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A 360-degree view of the molecule himastatin, which was first isolated from the bacterium Streptomyces himastatinicus. Himastatin shows antibiotic activity. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media
Biopixels
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Bioengineers were able to coax bacteria to blink in unison on microfluidic chips. This image shows a small chip with about 500 blinking bacterial colonies or biopixels. Jeff Hasty Lab, UC San Diego View Media
A dynamic model of the DNA helicase protein complex
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This short video shows a model of the DNA helicase in yeast. This DNA helicase has 11 proteins that work together to unwind DNA during the process of copying it, called DNA replication. Huilin Li, Stony Brook University View Media
Rabbit GPDA
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A crystal of rabbit GPDA protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Movie of in vitro assembly of a cell-signaling pathway
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T cells are white blood cells that are important in defending the body against bacteria, viruses and other pathogens. Xiaolei Su, HHMI Whitman Center of the Marine Biological Laboratory View Media
Trp_RS - tryptophanyl tRNA-synthetase family of enzymes
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This image represents the structure of TrpRS, a novel member of the tryptophanyl tRNA-synthetase family of enzymes. View Media
Cryo-ET cross-section of the Golgi apparatus
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On the left, a cross-section slice of a rat pancreas cell captured using cryo-electron tomography (cryo-ET). On the right, a 3D, color-coded version of the image highlighting cell structures. Xianjun Zhang, University of Southern California. View Media
Lipid raft
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Researchers have learned much of what they know about membranes by constructing artificial membranes in the laboratory. Judith Stoffer View Media
Yeast cell
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A whole yeast (Saccharomyces cerevisiae) cell viewed by X-ray microscopy. Inside, the nucleus and a large vacuole (red) are visible. Carolyn Larabell, University of California, San Francisco and the Lawrence Berkeley National Laboratory View Media
2-D NMR
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A two-dimensional NMR spectrum of a protein, in this case a 2D 1H-15N HSQC NMR spectrum of a 228 amino acid DNA/RNA-binding protein. Dr. Xiaolian Gao's laboratory at the University of Houston View Media
Tracking embryonic zebrafish cells
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To better understand cell movements in developing embryos, researchers isolated cells from early zebrafish embryos and grew them as clusters. Liliana Solnica-Krezel, Washington University School of Medicine in St. Louis. View Media
Two-headed Xenopus laevis tadpole
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Xenopus laevis, the African clawed frog, has long been used as a research organism for studying embryonic development. Michael Klymkowsky, University of Colorado, Boulder View Media
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 5
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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media
VDAC video 03
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This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media
Microtubules in hippocampal neurons
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Microtubules (magenta) in neurons of the hippocampus, a part of the brain involved in learning and memory. Microtubules are strong, hollow fibers that provide structural support to cells. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media
Birth of a yeast cell
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Yeast make bread, beer, and wine. And like us, yeast can reproduce sexually. A mother and father cell fuse and create one large cell that contains four offspring. Juergen Berger, Max Planck Institute for Developmental Biology, and Maria Langegger, Friedrich Miescher Laboratory of the Max Planck Society, Germany View Media
A molecular switch strips transcription factor from DNA
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In this video, Rice University scientists used molecular modeling with a mathematical algorithm called AWSEM (for associative memory, water-mediated, structure and energy model) and structural data to Davit Potoyan and Peter Wolynes View Media
Scanning electron microscopy of the ECM on the surface of a calf muscle
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This image shows the extracellular matrix (ECM) on the surface of a soleus (lower calf) muscle in light brown and blood vessels in pink. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
Pathways: What is Basic Science?
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Learn about basic science, sometimes called “pure” or “fundamental” science, and how it contributes to the development of medical treatments. National Institute of General Medical Sciences View Media
Intracellular forces
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Force vectors computed from actin cytoskeleton flow. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View Media
Disrupted and restored vasculature development in frog embryos
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Disassembly of vasculature and reassembly after addition and then washout of 250 µM TBZ in kdr:GFP frogs. Hye Ji Cha, University of Texas at Austin View Media
Lorsch Swearing In
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Jon Lorsch at his swearing in as NIGMS director in August 2013. Also shown are Francis Collins, NIH Director, and Judith Greenberg, former NIGMS Acting Director. View Media
Microtubule growth
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Map of microtubule growth rates. Rates are color coded. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View Media
Cryo-EM reveals how the HIV capsid attaches to a human protein to evade immune detection
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The illustration shows the capsid of human immunodeficiency virus (HIV) whose molecular features were resolved with cryo-electron microscopy (cryo-EM). Juan R. Perilla, University of Illinois at Urbana-Champaign View Media
NCMIR human spinal nerve
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Spinal nerves are part of the peripheral nervous system. They run within the spinal column to carry nerve signals to and from all parts of the body. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
How cilia do the wave
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Thin, hair-like biological structures called cilia are tiny but mighty. Zvonimir Dogic, Brandeis University View Media
Genetic mosaicism in fruit flies
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Fat tissue from the abdomen of a genetically mosaic adult fruit fly. Genetic mosaicism means that the fly has cells with different genotypes even though it formed from a single zygote. Akhila Rajan, Fred Hutchinson Cancer Center View Media
Cone cell
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The cone cell of the eye allows you to see in color. Appears in the NIGMS booklet Inside the Cell. Judith Stoffer View Media
Bioluminescent imaging in adult zebrafish - lateral and overhead view
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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View Media
Planarian stem cell colony
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Planarians are freshwater flatworms that have powerful abilities to regenerate their bodies, which would seem to make them natural model organisms in which to study stem cells. Peter Reddien, Whitehead Institute View Media
Rotavirus structure
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This image shows a computer-generated, three-dimensional map of the rotavirus structure. This virus infects humans and other animals and causes severe diarrhea in infants and young children. Bridget Carragher, The Scripps Research Institute, La Jolla, CA View Media
