Switch to Gallery View

Image and Video Gallery

This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Insulin production and fat sensing in fruit flies

6982

Fourteen neurons (magenta) in the adult Drosophila brain produce insulin, and fat tissue sends packets of lipids to the brain via the lipoprotein carriers (green). Akhila Rajan, Fred Hutchinson Cancer Center View Media

Confocal microscopy image of two Drosophila ovarioles

5772

Ovarioles in female insects are tubes in which egg cells (called oocytes) form at one end and complete their development as they reach the other end of the tube. 2004 Olympus BioScapes Competition View Media

Life in balance

1336

Mitosis creates cells, and apoptosis kills them. The processes often work together to keep us healthy. Judith Stoffer View Media

Disease-susceptible Arabidopsis leaf

2782

This is a magnified view of an Arabidopsis thaliana leaf after several days of infection with the pathogen Hyaloperonospora arabidopsidis. Jeff Dangl, University of North Carolina, Chapel Hill View Media

“Two-faced” Janus particle activating a macrophage

6801

A macrophage—a type of immune cell that engulfs invaders—“eats” and is activated by a “two-faced” Janus particle. Yan Yu, Indiana University, Bloomington. View Media

Protein crystals

1060

Structural biologists create crystals of proteins, shown here, as a first step in a process called X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Cell-free protein synthesizers

2360

Both instruments shown were developed by CellFree Sciences of Yokohama, Japan. Center for Eukaryotic Structural Genomics View Media

Arachnoidiscus diatom

6902

An Arachnoidiscus diatom with a diameter of 190µm. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media

Zinc finger

2426

The structure of a gene-regulating zinc finger protein bound to DNA. Jeremy M. Berg, National Institute of General Medical Sciences View Media

Research mentor and student

2767

A research mentor (Lori Eidson) and student (Nina Waldron, on the microscope) were 2009 members of the BRAIN (Behavioral Research Advancements In Neuroscience) program at Georgia State University in A Elizabeth Weaver, Georgia State University View Media

Movie of the 19S proteasome subunit processing a protein substrate

3764

The proteasome is a critical multiprotein complex in the cell that breaks down and recycles proteins that have become damaged or are no longer needed. Andreas Martin, HHMI View Media

Cell-like compartments from frog eggs 6

6593

Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media

Single-cell “radios” image

7021

Individual cells are color-coded based on their identity and signaling activity using a protein circuit technology developed by the Coyle Lab. Scott Coyle, University of Wisconsin-Madison. View Media

CRISPR illustration

3719

This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool.
National Institute of General Medical Sciences. View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 2

3414

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Superconducting magnet

1120

Superconducting magnet for NMR research, from the February 2003 profile of Dorothee Kern in Findings. Mike Lovett View Media

Plasma-Derived Membrane Vesicles

5887

This fiery image doesn’t come from inside a bubbling volcano. Instead, it shows animal cells caught in the act of making bubbles, or blebbing. Jeanne Stachowiak, University of Texas at Austin View Media

Xenopus laevis egg

2753

Xenopus laevis, the African clawed frog, has long been used as a model organism for studying embryonic development. Michael Klymkowsky, University of Colorado, Boulder View Media

Mitosis and meiosis compared-labeled

6788

Meiosis is used to make sperm and egg cells. During meiosis, a cell's chromosomes are copied once, but the cell divides twice. Judith Stoffer View Media

Dying melanoma cells

6966

Melanoma (skin cancer) cells undergoing programmed cell death, also called apoptosis. This process was triggered by raising the pH of the medium that the cells were growing in. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media

Golgi theories

1278

Two models for how material passes through the Golgi apparatus: the vesicular shuttle model and the cisternae maturation model. Judith Stoffer View Media

Induced stem cells from adult skin 04

2606

The human skin cells pictured contain genetic modifications that make them pluripotent, essentially equivalent to embryonic stem cells. James Thomson, University of Wisconsin-Madison View Media

Anti-tumor drug ecteinascidin 743 (ET-743), structure without hydrogens 01

2794

Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

Bacteriophage P22 capsid

5874

Cryo-electron microscopy (cryo-EM) has the power to capture details of proteins and other small biological structures at the molecular level.  This image shows proteins in the capsid, or outer co Dr. Wah Chiu, Baylor College of Medicine View Media

Protein kinases as cancer chemotherapy targets

7004

Protein kinases—enzymes that add phosphate groups to molecules—are cancer chemotherapy targets because they play significant roles in almost all aspects of cell function, are tightly regulated, and co Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Crab nerve cell

1247

Neuron from a crab showing the cell body (bottom), axon (rope-like extension), and growth cone (top right). Tina Weatherby Carvalho, University of Hawaii at Manoa View Media

Antitoxin GhoS (Illustration 2)

3428

Structure of the bacterial antitoxin protein GhoS. GhoS inhibits the production of a bacterial toxin, GhoT, which can contribute to antibiotic resistance. Rebecca Page and Wolfgang Peti, Brown University and Thomas K. Wood, Pennsylvania State University View Media

Cisternae maturation model

1307

Animation for the cisternae maturation model of Golgi transport. Judith Stoffer View Media

Cryo-electron tomography of a Caulobacter bacterium

6569

3D image of Caulobacter bacterium with various components highlighted: cell membranes (red and blue), protein shell (green), protein factories known as ribosomes (yellow), and storage granules Peter Dahlberg, Stanford University. View Media

PanC from M. tuberculosis

2383

Model of an enzyme, PanC, that is involved in the last step of vitamin B5 biosynthesis in Mycobacterium tuberculosis. PanC is essential for the growth of M. Mycobacterium Tuberculosis Center, PSI View Media

Structure of telomerase

3459

Scientists recently discovered the full molecular structure of telomerase, an enzyme important to aging and cancer. Jiansen Jiang, Edward J. Miracco, Z. Hong Zhou and Juli Feigon, University of California, Los Angeles; Kathleen Collins, University of California, Berkeley View Media

H1N1 Influenza Virus

6356

Related to image 6355. Dr. Rommie Amaro, University of California, San Diego View Media

Gene silencing

2318

Pretty in pink, the enzyme histone deacetylase (HDA6) stands out against a background of blue-tinted DNA in the nucleus of an Arabidopsis plant cell. Olga Pontes and Craig Pikaard, Washington University View Media

Beta-galactosidase montage showing cryo-EM improvement--transparent background

5882

Composite image of beta-galactosidase showing how cryo-EM’s resolution has improved dramatically in recent years. Older images to the left, more recent to the right. Veronica Falconieri, Sriram Subramaniam Lab, National Cancer Institute View Media

Fungal lipase (1)

2395

Crystals of fungal lipase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Ribosome illustration from PDB

5780

Ribosomes are complex machines made up of more than 50 proteins and three or four strands of genetic material called ribosomal RNA (rRNA). From PDB’s Molecule of the Month collection (direct link: http://pdb101.rcsb.org/motm/121) Molecule of the Month illustrations are available under a CC-BY-4.0 license. Attribution should be given to David S. Goodsell and the RCSB PDB. View Media

Three neurons and human ES cells

3290

The three neurons (red) visible in this image were derived from human embryonic stem cells. Undifferentiated stem cells are green here. Anirvan Ghosh lab, University of California, San Diego, via CIRM View Media

Cell division phases in Xenopus frog cells

3442

These images show three stages of cell division in Xenopus XL177 cells, which are derived from tadpole epithelial cells. They are (from top): metaphase, anaphase and telophase. Claire Walczak, who took them while working as a postdoc in the laboratory of Timothy Mitchison View Media

Cross section of a Drosophila melanogaster pupa lacking Draper

2759

In the absence of the engulfment receptor Draper, salivary gland cells (light blue) persist in the thorax of a developing Drosophila melanogaster pupa. Christina McPhee and Eric Baehrecke, University of Massachusetts Medical School View Media

Electrode probe on mouse Huntington's muscle cell

3479

Using an electrode, researchers apply an electrical pulse onto a piece of muscle tissue affected by Huntington's disease. Grigor Varuzhanyan and Andrew A. Voss, California State Polytechnic University View Media

Honeybees marked with paint

6756

Researchers doing behavioral experiments with honeybees sometimes use paint or enamel to give individual bees distinguishing marks. Gene Robinson, University of Illinois at Urbana-Champaign. View Media

VDAC-1 (2)

2491

The structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media

Microsporidia in roundworm 2

5778

Many disease-causing microbes manipulate their host’s metabolism and cells for their own ends. Keir Balla and Emily Troemel, University of California San Diego View Media

Ubiquitin-fold modifier 1 from C. elegans

2388

Solution NMR structure of protein target WR41 (left) from C. elegans. Northeast Structural Genomics Consortium View Media

Protein purification robot in action 01

2369

A robot is transferring 96 purification columns to a vacuum manifold for subsequent purification procedures. The Northeast Collaboratory for Structural Genomics View Media

Natcher Building 06

1086

NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View Media

Molecular model of freshly made Rous sarcoma virus (RSV)

3771

Viruses have been the foes of animals and other organisms for time immemorial. Boon Chong Goh, University of Illinois at Urbana-Champaign View Media

Pathways: What is It? | Why Scientists Study Cells

6540

Learn how curiosity about the world and our cells is key to scientific discoveries. National Institute of General Medical Sciences View Media

Sticky stem cells

3457

Like a group of barnacles hanging onto a rock, these human cells hang onto a matrix coated glass slide. Ankur Singh and Andrés García, Georgia Institute of Technology View Media

Mounting of protein crystals

2368

Automated methods using micromachined silicon are used at the Northeast Collaboratory for Structural Genomics to mount protein crystals for X-ray crystallography. The Northeast Collaboratory for Structural Genomics View Media