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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Cascade reaction promoted by water

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This illustration of an epoxide-opening cascade promoted by water emulates the proposed biosynthesis of some of the Red Tide toxins. Tim Jamison, Massachusetts Institute of Technology View Media

Bioluminescent imaging in adult zebrafish - lateral view

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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View Media

Nuclear Lamina – Three Views

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Three views of the entire nuclear lamina of a HeLa cell produced by tilted light sheet 3D single-molecule super-resolution imaging using a platform termed TILT3D. Anna-Karin Gustavsson, Ph.D. View Media

Seeing signaling protein activation in cells 03

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Cdc42, a member of the Rho family of small guanosine triphosphatase (GTPase) proteins, regulates multiple cell functions, including motility, proliferation, apoptosis, and cell morphology. Klaus Hahn, University of North Carolina, Chapel Hill Medical School View Media

Lily mitosis 01

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A light microscope image shows the chromosomes, stained dark blue, in a dividing cell of an African globe lily (Scadoxus katherinae). Andrew S. Bajer, University of Oregon, Eugene View Media

O2 reacting with a flavin-dependent enzyme

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Department of Biological Chemistry, University of Michigan View Media

Protein map

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Network diagram showing a map of protein-protein interactions in a yeast (Saccharomyces cerevisiae) cell. This cluster includes 78 percent of the proteins in the yeast proteome. Hawoong Jeong, KAIST, Korea View Media

Nucleotides make up DNA (with labels)

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DNA consists of two long, twisted chains made up of nucleotides. Each nucleotide contains one base, one phosphate molecule, and the sugar molecule deoxyribose. Crabtree + Company View Media

From DNA to Protein

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Nucleotides in DNA are copied into RNA, where they are read three at a time to encode the amino acids in a protein. Many parts of a protein fold as the amino acids are strung together. Crabtree + Company View Media

Zika virus

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Zika virus is shown in cross section at center left. On the outside, it includes envelope protein (red) and membrane protein (magenta) embedded in a lipid membrane (light purple). Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Trajectories of labeled cell receptors

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Trajectories of single molecule labeled cell surface receptors. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View Media

Jellyfish, viewed with ZEISS Lightsheet Z.1 microscope

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Jellyfish are especially good models for studying the evolution of embryonic tissue layers. Despite being primitive, jellyfish have a nervous system (stained green here) and musculature (red). Helena Parra, Pompeu Fabra University, Spain View Media

Tiny points of light in a quantum dot

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This fingertip-shaped group of lights is a microscopic crystal called a quantum dot. About 10,000 times thinner than a sheet of paper, the dot radiates brilliant colors under ultraviolet light. Sandra Rosenthal and James McBride, Vanderbilt University, and Stephen Pennycook, Oak Ridge National Laboratory View Media

Antitoxin GhoS (Illustration 1)

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Structure of the bacterial antitoxin protein GhoS. GhoS inhibits the production of a bacterial toxin, GhoT, which can contribute to antibiotic resistance. Rebecca Page and Wolfgang Peti, Brown University and Thomas K. Wood, Pennsylvania State University View Media

Circadian rhythm (with labels)

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The human body keeps time with a master clock called the suprachiasmatic nucleus or SCN. Crabtree + Company View Media

C. elegans showing internal structures

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An image of Caenorhabditis elegans, a tiny roundworm, showing internal structures including the intestine, pharynx, and body wall muscle. C. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media

Time-lapse video of floral pattern in a mixture of two bacterial species, Acinetobacter baylyi and Escherichia coli, grown on a semi-solid agar for 24 hours

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This time-lapse video shows the emergence of a flower-like pattern in a mixture of two bacterial species, motile Acinetobacter baylyi and non-motile Escherichia coli (green), that are gr L. Xiong et al, eLife 2020;9: e48885 View Media

E. Coli

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Thomas Deerinck, NCMIR View Media

Ribonuclease P structure

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Ribbon diagram showing the structure of Ribonuclease P with tRNA. PDB entry 3Q1Q, molecular modeling by Fred Friedman, NIGMS View Media

Cone snail shell

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A shell from the venomous cone snail Conus omaria, which lives in the Pacific and Indian oceans and eats other snails. Kerry Matz, University of Utah View Media

Lysosomes

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Lysosomes have powerful enzymes and acids to digest and recycle cell materials. Judith Stoffer View Media

Cell Nucleus and Lipid Droplets

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A cell nucleus (blue) surrounded by lipid droplets (yellow). James Olzmann, University of California, Berkeley View Media

Bovine trypsin

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A crystal of bovine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Rabbit GPDA

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A crystal of rabbit GPDA protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Zinc finger

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The structure of a gene-regulating zinc finger protein bound to DNA. Jeremy M. Berg, National Institute of General Medical Sciences View Media

Insulin production and fat sensing in fruit flies

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Fourteen neurons (magenta) in the adult Drosophila brain produce insulin, and fat tissue sends packets of lipids to the brain via the lipoprotein carriers (green). Akhila Rajan, Fred Hutchinson Cancer Center View Media

Shiga toxin being sorted inside a cell

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Shiga toxin (green) is sorted from the endosome into membrane tubules (red), which then pinch off and move to the Golgi apparatus. Somshuvra Mukhopadhyay, The University of Texas at Austin, and Adam D. Linstedt, Carnegie Mellon University View Media

Computer sketch of bird-and-flower DNA origami

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A computer-generated sketch of a DNA origami folded into a flower-and-bird structure. See also related image 3690. Hao Yan, Arizona State University View Media

An adult Hawaiian bobtail squid

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An adult female Hawaiian bobtail squid, Euprymna scolopes, with its mantle cavity exposed from the underside. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media

Endothelial cell

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This image shows two components of the cytoskeleton, microtubules (green) and actin filaments (red), in an endothelial cell derived from a cow lung. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media

Serum albumin structure 2

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Serum albumin (SA) is the most abundant protein in the blood plasma of mammals. SA has a characteristic heart-shape structure and is a highly versatile protein. Wladek Minor, University of Virginia View Media

“Two-faced” Janus particle activating a macrophage

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A macrophage—a type of immune cell that engulfs invaders—“eats” and is activated by a “two-faced” Janus particle. Yan Yu, Indiana University, Bloomington. View Media

Pig trypsin crystal

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A crystal of pig trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Mitochondria and endoplasmic reticulum

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A computer model shows how the endoplasmic reticulum is close to and almost wraps around mitochondria in the cell. The endoplasmic reticulum is lime green and the mitochondria are yellow. Bridget Wilson, University of New Mexico View Media

Chromosome inside nucleus

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The long, stringy DNA that makes up genes is spooled within chromosomes inside the nucleus of a cell. Crabtree + Company View Media

White Poppy (cropped)

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A cropped image of a white poppy. View poppy uncropped here 3424. Judy Coyle, Donald Danforth Plant Science Center View Media

Microscopy image of bird-and-flower DNA origami

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An atomic force microscopy image shows DNA folded into an intricate, computer-designed structure. Hao Yan, Arizona State University View Media

X-ray crystallography (with labels)

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X-ray crystallography allows researchers to see structures too small to be seen by even the most powerful microscopes. Crabtree + Company View Media

Modeling disease spread

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What looks like a Native American dream catcher is really a network of social interactions within a community. Stephen Eubank, University of Virginia Biocomplexity Institute (formerly Virginia Bioinformatics Institute) View Media

Natcher Building 02

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NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View Media

Structure of telomerase

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Scientists recently discovered the full molecular structure of telomerase, an enzyme important to aging and cancer. Jiansen Jiang, Edward J. Miracco, Z. Hong Zhou and Juli Feigon, University of California, Los Angeles; Kathleen Collins, University of California, Berkeley View Media

Cytoscape network wiring diagram 2

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This image integrates the thousands of known molecular and genetic interactions happening inside our bodies using a computer program called Cytoscape. Trey Ideker, University of California, San Diego View Media

Active Site of E. coli response regulator PhoB

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Active site of E. coli response regulator PhoB. Ann Stock, Rutgers University View Media

Drosophila (fruit fly) myosin 1D motility assay

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Actin gliding powered by myosin 1D. Note the counterclockwise motion of the gliding actin filaments. Serapion Pyrpassopoulos and E. Michael Ostap, University of Pennsylvania View Media

Life of an AIDS virus (with labels)

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HIV is a retrovirus, a type of virus that carries its genetic material not as DNA but as RNA. Crabtree + Company View Media

Alternative splicing (with labels)

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Arranging exons in different patterns, called alternative splicing, enables cells to make different proteins from a single gene. Featured in The New Genetics. Crabtree + Company View Media

Red blood cells

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This image of human red blood cells was obtained with the help of a scanning electron microscope, an instrument that uses a finely focused electron beam to yield detailed images of the surface of a sa Tina Weatherby Carvalho, University of Hawaii at Manoa View Media

Sea urchin embryo 03

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Stereo triplet of a sea urchin embryo stained to reveal actin filaments (orange) and microtubules (blue). George von Dassow, University of Washington View Media

Bacillus anthracis being killed

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Bacillus anthracis (anthrax) cells being killed by a fluorescent trans-translation inhibitor, which disrupts bacterial protein synthesis. John Alumasa, Keiler Laboratory, Pennsylvania State University View Media

HIV Infected Cell

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The human immunodeficiency virus (HIV), shown here as tiny purple spheres, causes the disease known as AIDS (for acquired immunodeficiency syndrome). Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media