Image and Video Gallery

This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Lorsch Swearing In

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Jon Lorsch at his swearing in as NIGMS director in August 2013. Also shown are Francis Collins, NIH Director, and Judith Greenberg, former NIGMS Acting Director. View Media

Pathways – Bacteria vs. Viruses: What's the Difference?

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Learn about how bacteria and viruses differ, how they each can make you sick, and how they can or cannot be treated. National Institute of General Medical Sciences View Media

Genetic mosaicism in fruit flies

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Fat tissue from the abdomen of a genetically mosaic adult fruit fly. Genetic mosaicism means that the fly has cells with different genotypes even though it formed from a single zygote. Akhila Rajan, Fred Hutchinson Cancer Center View Media

Actin flow

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Speckle microscopy analysis of actin cytoskeleton force. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View Media

Introns (with labels)

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Genes are often interrupted by stretches of DNA (introns, blue) that do not contain instructions for making a protein. Crabtree + Company View Media

Full-length serotonin receptor (ion channel)

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A 3D reconstruction, created using cryo-electron microscopy, of an ion channel known as the full-length serotonin receptor in complex with the antinausea drug granisetron (orange). Sudha Chakrapani, Case Western Reserve University School of Medicine. View Media

Nucleotides make up DNA (with labels)

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DNA consists of two long, twisted chains made up of nucleotides. Each nucleotide contains one base, one phosphate molecule, and the sugar molecule deoxyribose. Crabtree + Company View Media

Q fever bacteria in an infected cell

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This image shows Q fever bacteria (yellow), which infect cows, sheep, and goats around the world and can infect humans, as well. When caught early, Q fever can be cured with antibiotics. Robert Heinzen, Elizabeth Fischer, and Anita Mora, National Institute of Allergy and Infectious Diseases, National Institutes of Health View Media

Dicer generates microRNAs (with labels)

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The enzyme Dicer generates microRNAs by chopping larger RNA molecules into tiny Velcro^®-like pieces. MicroRNAs stick to mRNA molecules and prevent the mRNAs from being made into proteins. Crabtree + Company View Media

Beta 2-adrenergic receptor

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The receptor is shown bound to a partial inverse agonist, carazolol. Raymond Stevens, The Scripps Research Institute View Media

Bacteria working to eat

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Gram-negative bacteria perform molecular acrobatics just to eat. Because they're encased by two membranes, they must haul nutrients across both. Emad Tajkhorshid, University of Illinois at Urbana-Champaign View Media

Network Map

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This network map shows the overlap (green) between the long QT syndrome (yellow) and epilepsy (blue) protein-interaction neighborhoods located within the human interactome. Seth Berger, Mount Sinai School of Medicine View Media

Golden gene chips

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A team of chemists and physicists used nanotechnology and DNA's ability to self-assemble with matching RNA to create a new kind of chip for measuring gene activity. Hao Yan and Yonggang Ke, Arizona State University View Media

Hen egg lysozyme (1)

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Crystals of hen egg lysozyme protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Activated mast cell surface

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A scanning electron microscope image of an activated mast cell. This image illustrates the interesting topography of the cell membrane, which is populated with receptors. Bridget Wilson, University of New Mexico View Media

LONI movie

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Related to image 5871. View Media

HeLa cells

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Scanning electron micrograph of just-divided HeLa cells. Zeiss Merlin HR-SEM. National Center for Microscopy and Imaging Research View Media

Genetically identical mycobacteria respond differently to antibiotic 2

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Antibiotic resistance in microbes is a serious health concern. So researchers have turned their attention to how bacteria undo the action of some antibiotics. Bree Aldridge, Tufts University View Media

Human blood cells with Borrelia hermsii, a bacterium that causes relapsing fever

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Relapsing fever is caused by a bacterium and transmitted by certain soft-bodied ticks or body lice. The disease is seldom fatal in humans, but it can be very serious and prolonged. NIAID View Media

Multivesicular bodies containing intralumenal vesicles assemble at the vacuole 3

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Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View Media

Active Site of E. coli response regulator PhoB

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Active site of E. coli response regulator PhoB. Ann Stock, Rutgers University View Media

Nerve cell

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Nerve cells have long, invisibly thin fibers that carry electrical impulses throughout the body. Some of these fibers extend about 3 feet from the spinal cord to the toes. Judith Stoffer View Media

Protein formation

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Proteins are 3D structures made up of smaller units. DNA is transcribed to RNA, which in turn is translated into amino acids. NIGMS, with the folded protein illustration adapted from Jane Richardson, Duke University Medical Center View Media

Three muscle fibers; the middle has a defect found in some neuromuscular diseases

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Of the three muscle fibers shown here, the one on the right and the one on the left are normal. The middle fiber is deficient a large protein called nebulin (blue). Christopher Pappas and Carol Gregorio, University of Arizona View Media

Fruitful dyes

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These colorful, computer-generated ribbons show the backbone of a molecule that glows a fluorescent red. Roger Y. Tsien, University of California, San Diego View Media

Mitosis and meiosis compared-labeled

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Meiosis is used to make sperm and egg cells. During meiosis, a cell's chromosomes are copied once, but the cell divides twice. Judith Stoffer View Media

Crystals of CCD-1 in complex with cefotaxime

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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media

Protein from Arabidopsis thaliana

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NMR solution structure of a plant protein that may function in host defense. This protein was expressed in a convenient and efficient wheat germ cell-free system. Center for Eukaryotic Structural Genomics View Media

Chromosome fiber 01

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This microscopic image shows a chromatin fiber--a DNA molecule bound to naturally occurring proteins. Marc Green and Susan Forsburg, University of Southern California View Media

Circadian rhythms and the SCN

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Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. NIGMS View Media

Microtubules and tau aggregates

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Microtubules (magenta) and tau protein (light blue) in a cell model of tauopathy. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media

Lily mitosis 12

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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View Media

VDAC video 02

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This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media

DNase

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Crystals of DNase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Tracking cells in a gastrulating zebrafish embryo

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During development, a zebrafish embryo is transformed from a ball of cells into a recognizable body plan by sweeping convergence and extension cell movements. This process is called gastrulation. Liliana Solnica-Krezel, Washington University School of Medicine in St. Louis. View Media

Himastatin

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A model of the molecule himastatin, which was first isolated from the bacterium Streptomyces himastatinicus. Himastatin shows antibiotic activity. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media

Vesicular shuttle model

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Animation for the vesicular shuttle model of Golgi transport. Judith Stoffer View Media

Sea urchin embryo 04

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Stereo triplet of a sea urchin embryo stained to reveal actin filaments (orange) and microtubules (blue). George von Dassow, University of Washington View Media

Epithelial cells

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This image mostly shows normal cultured epithelial cells expressing green fluorescent protein targeted to the Golgi apparatus (yellow-green) and stained for actin (magenta) and DNA (cyan). Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Fluorescent C. elegans showing muscle and ribosomal protein

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C. elegans, a tiny roundworm, with a ribosomal protein glowing red and muscle fibers glowing green. Researchers used these worms to study a molecular pathway that affects aging. Jarod Rollins, Mount Desert Island Biological Laboratory. View Media

Pig trypsin (3)

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Crystals of porcine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Taste buds signal different tastes through ATP release

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Taste buds in a mouse tongue epithelium with types I, II, and III taste cells visualized by cell-type-specific fluorescent antibodies. Aki Taruno, Perelman School of Medicine, University of Pennsylvania View Media

Mouse sperm sections

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This transmission electron micrograph shows sections of mouse sperm tails, or flagella. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media

Microscopy image of bird-and-flower DNA origami

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An atomic force microscopy image shows DNA folded into an intricate, computer-designed structure. Hao Yan, Arizona State University View Media

Skin cancer cells (squamous cell carcinoma)

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This image shows the uncontrolled growth of cells in squamous cell carcinoma, the second most common form of skin cancer. If caught early, squamous cell carcinoma is usually not life-threatening. Markus Schober and Elaine Fuchs, The Rockefeller University View Media

ATP Synthase

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Atomic model of the membrane region of the mitochondrial ATP synthase built into a cryo-EM map at 3.6 Å resolution. ATP synthase is the primary producer of ATP in aerobic cells. Bridget Carragher, <a href="http://nramm.nysbc.org/">NRAMM National Resource for Automated Molecular Microscopy</a> View Media

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