Image and Video Gallery
This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Neurons from human ES cells
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These neural precursor cells were derived from human embryonic stem cells. The neural cell bodies are stained red, and the nuclei are blue. Xianmin Zeng lab, Buck Institute for Age Research, via CIRM View MediaPlastic-eating enzymes
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PETase enzyme degrades polyester plastic (polyethylene terephthalate, or PET) into monohydroxyethyl terephthalate (MHET). Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaSkin cross-section
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Cross-section of skin anatomy shows layers and different tissue types. National Institutes of Health Medical Arts View MediaCytochrome structure with anticancer drug
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This image shows the structure of the CYP17A1 enzyme (ribbons colored from blue N-terminus to red C-terminus), with the associated heme colored black. Emily Scott, University of Kansas View MediaVDAC video 02
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This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View MediaZ rings in bacterial division
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Lab-made liposomes contract where Z rings have gathered together and the constriction forces are greatest (arrows). Masaki Osawa, Duke University View MediaHoneybee brain
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Insect brains, like the honeybee brain shown here, are very different in shape from human brains. Gene Robinson, University of Illinois at Urbana-Champaign. View MediaDolly the sheep
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Scientists in Scotland were the first to clone an animal, this sheep named Dolly. She later gave birth to Bonnie, the lamb next to her. View MediaBacterial cells aggregating above the light organ of the Hawaiian bobtail squid
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A light organ (~0.5 mm across) of a juvenile Hawaiian bobtail squid, Euprymna scolopes. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View MediaRNase A (2)
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A crystal of RNase A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaGlowing glycans
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Sugars light up the cells in this jaw of a 3-day-old zebrafish embryo and highlight a scientific first: labeling and tracking the movements of sugar chains called glycans in a living organism. Carolyn Bertozzi, University of California, Berkeley View MediaHistones in chromatin (with labels)
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Histone proteins loop together with double-stranded DNA to form a structure that resembles beads on a string. Crabtree + Company View MediaProteins related to myotonic dystrophy
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Myotonic dystrophy is thought to be caused by the binding of a protein called Mbnl1 to abnormal RNA repeats. Manuel Ares, University of California, Santa Cruz View MediaCryo-ET cross-section of a rat pancreas cell
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On the left, a cross-section slice of a rat pancreas cell captured using cryo-electron tomography (cryo-ET). On the right, a 3D, color-coded version of the image highlighting cell structures. Xianjun Zhang, University of Southern California. View MediaTelomeres
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The 46 human chromosomes are shown in blue, with the telomeres appearing as white pinpoints. Hesed Padilla-Nash and Thomas Ried, the National Cancer Institute, a part of NIH View MediaStatistical cartography
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Like a world of its own, this sphere represents all the known chemical reactions in the E. coli bacterium. Luis A. Nunes Amaral, Northwestern University View MediaFruit fly in the pink
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Fruit flies are a common model organism for basic medical research. Crabtree + Company View MediaSingle-cell “radios” video
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Individual cells are color-coded based on their identity and signaling activity using a protein circuit technology developed by the Coyle Lab. Scott Coyle, University of Wisconsin-Madison. View MediaNucleolus subcompartments spontaneously self-assemble 4
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What looks a little like distant planets with some mysterious surface features are actually assemblies of proteins normally found in the cell's nucleolus, a small but very important protein complex lo Nilesh Vaidya, Princeton University View MediaGolgi theories
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Two models for how material passes through the Golgi apparatus: the vesicular shuttle model and the cisternae maturation model. Judith Stoffer View MediaSkin cancer cells (squamous cell carcinoma)
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This image shows the uncontrolled growth of cells in squamous cell carcinoma, the second most common form of skin cancer. If caught early, squamous cell carcinoma is usually not life-threatening. Markus Schober and Elaine Fuchs, The Rockefeller University View MediaSingle-Molecule Imaging
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This is a super-resolution light microscope image taken by Hiro Hakozaki and Masa Hoshijima of NCMIR. Tom Deerinck, NCMIR View MediaMitosis and meiosis compared-labeled
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Meiosis is used to make sperm and egg cells. During meiosis, a cell's chromosomes are copied once, but the cell divides twice. Judith Stoffer View MediaDeveloping nerve cells
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These developing mouse nerve cells have a nucleus (yellow) surrounded by a cell body, with long extensions called axons and thin branching structures called dendrites. Torsten Wittmann, University of California, San Francisco View MediaRNA strand
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Ribonucleic acid (RNA) has a sugar-phosphate backbone and the bases adenine (A), cytosine (C), guanine (G), and uracil (U). Crabtree + Company View MediaHungry, hungry macrophages
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Macrophages (green) are the professional eaters of our immune system. Meghan Morrissey, University of California, Santa Barbara. View MediaFruit fly starvation leads to adipokine accumulation
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Adult Drosophila abdominal fat tissue showing cell nuclei labelled in magenta. Akhila Rajan, Fred Hutchinson Cancer Center View MediaCentral dogma, illustrated (with labels and numbers for stages)
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DNA encodes RNA, which encodes protein. DNA is transcribed to make messenger RNA (mRNA). The mRNA sequence (dark red strand) is complementary to the DNA sequence (blue strand). Crabtree + Company View MediaAutomated crystal screening system
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Automated crystal screening systems such as the one shown here are becoming a common feature at synchrotron and other facilities where high-throughput crystal structure determination is being carried Southeast Collaboratory for Structural Genomics View MediaSponge
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Many of today's medicines come from products found in nature, such as this sponge found off the coast of Palau in the Pacific Ocean. Phil Baran, Scripps Research Institute View MediaVDAC video 03
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This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View MediaThe 26S proteasome engages with a protein substrate
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The proteasome is a critical multiprotein complex in the cell that breaks down and recycles proteins that have become damaged or are no longer needed. Andreas Martin, HHMI View MediaScanning electron microscopy of collagen fibers
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This image shows collagen, a fibrous protein that's the main component of the extracellular matrix (ECM). Collagen is a strong, ropelike molecule that forms stretch-resistant fibers. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaATP synthase (with labels)
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The world's smallest motor, ATP synthase, generates energy for the cell. See image 2517 for an unlabeled version of this illustration. Crabtree + Company View MediaTrigonium diatom
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A Trigonium diatom imaged by a quantitative orientation-independent differential interference contrast (OI-DIC) microscope. Michael Shribak, Marine Biological Laboratory/University of Chicago. View MediaCRISPR Illustration Frame 5
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. This is the fifthframe in a series of five. View MediaPlanting roots
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At the root tips of the mustard plant Arabidopsis thaliana (red), two proteins work together to control the uptake of water and nutrients. Philip Benfey, Duke University View MediaFruit fly brain responds to adipokines
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Drosophila adult brain showing that an adipokine (fat hormone) generates a response from neurons (aqua) and regulates insulin-producing neurons (red).Akhila Rajan, Fred Hutchinson Cancer Center View Media
Pathways: What is Basic Science?
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Learn about basic science, sometimes called “pure” or “fundamental” science, and how it contributes to the development of medical treatments. National Institute of General Medical Sciences View MediaColony of human ES cells
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A colony of human embryonic stem cells (light blue) grows on fibroblasts (dark blue). California Institute for Regenerative Medicine View MediaBiosensors illustration
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A rendering of an activity biosensor image overlaid with a cell-centered frame of reference used for image analysis of signal transduction. Gaudenz Danuser, Harvard Medical School View MediaHippocampal neuron from rodent brain
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Hippocampal neuron from rodent brain with dendrites shown in blue. The hundreds of tiny magenta, green and white dots are the dendritic spines of excitatory synapses. Shelley Halpain, UC San Diego View MediaNatcher Building 10
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NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View MediaNetwork diagram of genes, cellular components and processes (unlabeled)
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This image shows the hierarchical ontology of genes, cellular components and processes derived from large genomic datasets. From Dutkowski et al. Janusz Dutkowski and Trey Ideker View MediaZebrafish pigment cell
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Pigment cells are cells that give skin its color. David Parichy, University of Washington View MediaProtective membrane and membrane proteins of the dengue virus visualized with cryo-EM
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Dengue virus is a mosquito-borne illness that infects millions of people in the tropics and subtropics each year. Like many viruses, dengue is enclosed by a protective membrane. Hong Zhou, UCLA View MediaNatcher Building 07
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NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View MediaAxolotl
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An axolotl—a type of salamander—that has been genetically modified so that its developing nervous system glows purple and its Schwann cell nuclei appear light blue. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View MediaLife of an AIDS virus
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HIV is a retrovirus, a type of virus that carries its genetic material not as DNA but as RNA. Crabtree + Company View MediaDNA replication illustration
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During DNA replication, each strand of the original molecule acts as a template for the synthesis of a new, complementary DNA strand. Crabtree + Company View Media