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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Mouse embryo showing Smad4 protein
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This eerily glowing blob isn't an alien or a creature from the deep sea--it's a mouse embryo just eight and a half days old. The green shell and core show a protein called Smad4. Kenneth Zaret, Fox Chase Cancer Center View MediaProtein involved in cell division from Mycoplasma pneumoniae
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Model of a protein involved in cell division from Mycoplasma pneumoniae. This model, based on X-ray crystallography, revealed a structural domain not seen before. Berkeley Structural Genomics Center, PSI View MediaCellular aging
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A protein called tubulin (green) accumulates in the center of a nucleus (outlined in pink) from an aging cell. Maximiliano D'Angelo and Martin Hetzer, Salk Institute View MediaBubonic plague bacteria on part of the digestive system in a rat flea
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Here, bubonic plague bacteria (yellow) are shown in the digestive system of a rat flea (purple). The bubonic plague killed a third of Europeans in the mid-14th century. NIAID View MediaRNA interference (with labels)
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RNA interference or RNAi is a gene-silencing process in which double-stranded RNAs trigger the destruction of specific RNAs. Crabtree + Company View MediaHippocampal neuron in culture
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Hippocampal neuron in culture. Dendrites are green, dendritic spines are red and DNA in cell's nucleus is blue. Shelley Halpain, UC San Diego View MediaSection of an electron density map
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Electron density maps such as this one are generated from the diffraction patterns of X-rays passing through protein crystals. The Southeast Collaboratory for Structural Genomics View MediaHuman Adenovirus
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The cryo-EM structure of human adenovirus D26 (HAdV-D26) at near atomic resolution (3.7 Å), determined in collaboration with the NRAMM facility*. National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View MediaNociceptin/orphanin FQ peptide opioid receptor
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The receptor is shown bound to an antagonist, compound-24 Raymond Stevens, The Scripps Research Institute View MediaFruit fly embryo
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Cells in an early-stage fruit fly embryo, showing the DIAP1 protein (pink), an inhibitor of apoptosis. Hermann Steller, Rockefeller University View MediaCryo-electron microscopy of the dengue virus showing protective membrane and membrane proteins
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Dengue virus is a mosquito-borne illness that infects millions of people in the tropics and subtropics each year. Like many viruses, dengue is enclosed by a protective membrane. Hong Zhou, UCLA View MediaVDAC video 02
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This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View MediaProtein purification robot
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Irina Dementieva, a biochemist, and Youngchang Kim, a biophysicist and crystallographer, work with the first robot of its type in the U.S. to automate protein purification. Midwest Center for Structural Genomics View MediaAnti-tumor drug ecteinascidin 743 (ET-743) with hydrogens 02
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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View MediaWorm sperm
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To develop a system for studying cell motility in unnatrual conditions -- a microscope slide instead of the body -- Tom Roberts and Katsuya Shimabukuro at Florida State University disassembled and rec Tom Roberts, Florida State University View MediaCalling Cards in a mouse brain
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The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. Allen Yen, Lab of Joseph Dougherty, Washington University School of Medicine in St. Louis. View MediaTelomeres on outer edge of nucleus during cell division
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New research shows telomeres moving to the outer edge of the nucleus after cell division, suggesting these caps that protect chromosomes also may play a role in organizing DNA. Laure Crabbe, Jamie Kasuboski and James Fitzpatrick, Salk Institute for Biological Studies View MediaRecombinant DNA
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To splice a human gene into a plasmid, scientists take the plasmid out of an E. coli bacterium, cut the plasmid with a restriction enzyme, and splice in human DNA. Crabtree + Company View MediaEpithelial cells
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This image mostly shows normal cultured epithelial cells expressing green fluorescent protein targeted to the Golgi apparatus (yellow-green) and stained for actin (magenta) and DNA (cyan). Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaWorms and human infertility
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This montage of tiny, transparent C. elegans--or roundworms--may offer insight into understanding human infertility. Abby Dernburg, Lawrence Berkeley National Laboratory View MediaHen egg lysozyme (2)
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A crystal of hen egg lysozyme protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaZebrafish embryo showing vasculature
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A zebrafish embryo. The blue areas are cell bodies, the green lines are blood vessels, and the red glow is blood. Kevin Eliceiri, University of Wisconsin-Madison. View MediaHistones in chromatin
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Histone proteins loop together with double-stranded DNA to form a structure that resembles beads on a string. Crabtree + Company View MediaMeiosis illustration
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Meiosis is the process whereby a cell reduces its chromosomes from diploid to haploid in creating eggs or sperm. Crabtree + Company View MediaHeLa cells
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Multiphoton fluorescence image of HeLa cells with cytoskeletal microtubules (magenta) and DNA (cyan). Nikon RTS2000MP custom laser scanning microscope. National Center for Microscopy and Imaging Research (NCMIR) View MediaBody toxins
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Body organs such as the liver and kidneys process chemicals and toxins. These "target" organs are susceptible to damage caused by these substances. Crabtree + Company View MediaA chromosome goes missing in anaphase
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Anaphase is the critical step during mitosis when sister chromosomes are disjoined and directed to opposite spindle poles, ensuring equal distribution of the genome during cell division. View MediaDrugs enter skin (with labels)
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Drugs enter different layers of skin via intramuscular, subcutaneous, or transdermal delivery methods. See image 2531 for an unlabeled version of this illustration. Crabtree + Company View MediaThe 26S proteasome engages with a protein substrate
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The proteasome is a critical multiprotein complex in the cell that breaks down and recycles proteins that have become damaged or are no longer needed. Andreas Martin, HHMI View MediaFly by night
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This fruit fly expresses green fluorescent protein (GFP) in the same pattern as the period gene, a gene that regulates circadian rhythm and is expressed in all sensory neurons on the surface of the fl Jay Hirsh, University of Virginia View MediaHuman skeletal muscle
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Cross section of human skeletal muscle. Image taken with a confocal fluorescent light microscope. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaAminopeptidase N from N. meningitidis
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Model of the enzyme aminopeptidase N from the human pathogen Neisseria meningitidis, which can cause meningitis epidemics. Midwest Center for Structural Genomics, PSI View MediaMyelinated axons 2
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Top view of myelinated axons in a rat spinal root. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaCiclo circadiano de un adolescente típico
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Los ritmos circadianos son cambios físicos, mentales y conductuales que siguen un ciclo de 24 horas. NIGMS View MediaFly cells
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If a picture is worth a thousand words, what's a movie worth? Denise Montell, Johns Hopkins University School of Medicine View MediaSpace-filling model of a cefotaxime-CCD-1 complex
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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View MediaSmooth muscle from human ES cells
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These smooth muscle cells were derived from human embryonic stem cells. The nuclei are stained blue, and the proteins of the cytoskeleton are stained green. Alexey Terskikh lab, Burnham Institute for Medical Research, via CIRM View MediaHeart rates time series image
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These time series show the heart rates of four different individuals. Madalena Costa and Ary Goldberger, Beth Israel Deaconess Medical Center View MediaDiversity oriented synthesis: generating skeletal diversity using folding processes
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This 1 1/2-minute video animation was produced for chemical biologist Stuart Schreiber's lab page. The animation shows how diverse chemical structures can be produced in the lab. Eric Keller View MediaDividing cells showing chromosomes and cell skeleton
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This pig cell is in the process of dividing. The chromosomes (purple) have already replicated and the duplicates are being pulled apart by fibers of the cell skeleton known as microtubules (green). Nasser Rusan, National Heart, Lung, and Blood Institute, National Institutes of Health View MediaFlu virus proteins during self-replication
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Influenza (flu) virus proteins in the act of self-replication. Viral nucleoprotein (blue) encapsidates [encapsulates] the RNA genome (green). Scripps Research Institute in La Jolla, CA View MediaCellular metropolis
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Like a major city, a cell teems with specialized workers that carry out its daily operations--making energy, moving proteins, or helping with other tasks. Kathryn Howell, University of Colorado Health Sciences Center View MediaCross section of a Drosophila melanogaster pupa
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This photograph shows a magnified view of a Drosophila melanogaster pupa in cross section. Compare this normal pupa to one that lacks an important receptor, shown in image 2759. Christina McPhee and Eric Baehrecke, University of Massachusetts Medical School View MediaDividing yeast cells with spindle pole bodies and contractile rings
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During cell division, spindle pole bodies (glowing dots) move toward the ends of yeast cells to separate copied genetic information. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View MediaMovie of in vitro assembly of a cell-signaling pathway
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T cells are white blood cells that are important in defending the body against bacteria, viruses and other pathogens. Xiaolei Su, HHMI Whitman Center of the Marine Biological Laboratory View MediaPolarized cells- 01
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Cells move forward with lamellipodia and filopodia supported by networks and bundles of actin filaments. Proper, controlled cell movement is a complex process. Rong Li and Praveen Suraneni, Stowers Institute for Medical Research View MediaCerebellum: the brain's locomotion control center
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The cerebellum of a mouse is shown here in cross-section. The cerebellum is the brain's locomotion control center. Thomas Deerinck, National Center for Microscopy and Imaging Research, University of California, San Diego View MediaBacteriophage P22 capsid, detail
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Detail of a subunit of the capsid, or outer cover, of bacteriophage P22, a virus that infects the Salmonella bacteria. Dr. Wah Chiu, Baylor College of Medicine View MediaNerve ending
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A scanning electron microscope picture of a nerve ending. It has been broken open to reveal vesicles (orange and blue) containing chemicals used to pass messages in the nervous system. Tina Weatherby Carvalho, University of Hawaii at Manoa View MediaFour timepoints in gastrulation
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It has been said that gastrulation is the most important event in a person's life. Bob Goldstein, University of North Carolina, Chapel Hill View Media